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Journal of Medicinal Chemistry, ISSN 0022-2623, 07/1999, Volume 42, Issue 14, pp. 2493 - 2497
The ecteinascidins (Ets), which are natural products derived from marine tunicates, exhibit potent antitumor activity. Of the numerous Ets isolated, Et 743 is... 
TURBINATA | CROSS-LINK | GUANINE N2 | CHEMISTRY, MEDICINAL | ADDUCT | Autoradiography | Isoquinolines - chemistry | Naphthyridines - chemistry | Oligonucleotides - chemistry | DNA - chemistry | Antibiotics, Antineoplastic - chemistry | Antineoplastic Agents, Alkylating - chemistry | Dioxoles - chemistry | Tetrahydroisoquinolines | ecteinascidin
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 03/2019, Volume 58, Issue 12, pp. 3972 - 3975
Journal Article
Cancer, ISSN 0008-543X, 08/2003, Volume 98, Issue 4, pp. 832 - 840
Journal Article
Synthesis, ISSN 0039-7881, 12/2006, Volume 2006, Issue 23, pp. 4081 - 4086
Abstract The Mannich reaction between a phenol and a chiral oxazinone is used as a key step in a concise synthesis of a highly functionalized, orthogonally... 
special topic | Pomerantz-Fritsch cyclization | Ecteinascidin 743 (Et 743) | Oxazinone | Mannich reaction | Tetrahydroisoquinoline | CORE | ENANTIOSELECTIVE SYNTHESIS | ANALOGS | ALKYLATION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | ecteinascidin 743 (Et 743) | CONSTRUCTION | tetrahydroisoquinoline | CYANOSAFRACIN-B | DERIVATIVES | ABC RING MODEL | oxazinone | ALKALOIDS
Journal Article
中国化学:英文版, ISSN 1001-604X, 2012, Volume 30, Issue 1, pp. 43 - 46
Ecteinascidin 743 from sea squirt is one of the most original anti-tumoral activity compounds, as proven by the Natural Cancer Institute. Ecteinascidin 743... 
固相提取 | 液体萃取 | 分子印迹聚合物 | 提取纯化 | 抗肿瘤活性 | 海鞘 | 选择性分离 | 相对标准偏差 | molecular imprinted polymer | solid‐phase extraction | ecteinascidin 743 | sea squirt | solid-phase extraction | PRECONCENTRATION | ANTIBODIES | CARBON | ET-743 | SELECTIVITY | CHEMISTRY, MULTIDISCIPLINARY | Polymers | Polymer industry
Journal Article
Organic Letters, ISSN 1523-7060, 01/2002, Volume 4, Issue 1, pp. 43 - 46
Journal Article
Letters in Organic Chemistry, ISSN 1570-1786, 12/2011, Volume 8, Issue 10, pp. 686 - 689
A practical synthetic route of DOPA derivative 2, which should be useful for direct biosynthetic production of potent antitumor natural products, saframycins... 
Non-natural amino acid | 3,4-dihydroxyphenylalanine | Ecteinascidin 743 | Biosynthesis | DOPA | Saframycin | ANTIBIOTICS | TYROSINE | non-natural amino acid | CHEMISTRY, ORGANIC | ecteinascidin 743 | saframycin | REIMER-TIEMANN
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/1998, Volume 120, Issue 10, pp. 2490 - 2491
Ecteinascidin 743 (1), the first of a novel class of therapeutically significant marine alkaloids, has shown good activity against a variety of solid tumor... 
TURBINATA | CHEMISTRY, MULTIDISCIPLINARY | INVITRO INTERACTION | Alkaloids | Research | Catalysis | Antibiotics | Alkylation | Guanine | carbinolamine | Ecteinascidin 743 | saframycin S | naphthyridinomycin | anthramycin
Journal Article
Synlett, ISSN 0936-5214, 1999, Issue 7, pp. 1103 - 1105
During the course of synthetic study on ecteinascidin 743 (1), key intermediate 5 was prepared. Stereocontrolled synthesis of 5 from D-glucose was accomplished... 
Ecteinascidin 743 | D-glucose | Imine | Bicyclo [3.3.1] system | imine | TURBINATA | CHEMISTRY, ORGANIC | CRYSTAL-STRUCTURES | INTERMEDIATE | bicyclo [3.3.1] system | ecteinascidin 743 | CARIBBEAN TUNICATE
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 09/2018, Volume 83, Issue 17, pp. 10580 - 10588
A diastereoselective α-sulfenylation of chiral α-aryl/alkyl N-tert-butanesulfinyl imidates has been developed. Suitable sulfur electrophiles can be used as... 
ACID-DERIVATIVES | CHOLESTEROL ACYLTRANSFERASE | CHIRAL BUILDING-BLOCKS | ENANTIOSELECTIVE SYNTHESIS | CATALYZED ASYMMETRIC SULFENYLATION | ONE-POT SYNTHESIS | ELECTROPHILIC TRIFLUOROMETHYLTHIOLATION | CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | 3-SUBSTITUTED OXINDOLES | ECTEINASCIDIN 743
Journal Article
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 30, pp. 7334 - 7344
(-)-Renieramycin T, an interesting tetrahydroisoquinolinequinone alkaloid with a novel renieramycin-ecteinascidin mixed framework, is synthesized from the... 
ANTITUMOR AGENTS | CYANOSAFRACIN B | PALLADIUM | ENANTIOSELECTIVE SYNTHESIS | PHTHALASCIDIN | NUDIBRANCH JORUNNA-FUNEBRIS | CHEMISTRY, ORGANIC | FORMAL TOTAL-SYNTHESIS | RENIERAMYCIN-TYPE ALKALOIDS | CARIBBEAN TUNICATE | ECTEINASCIDIN 743
Journal Article
Annals of Oncology, ISSN 0923-7534, 9/1998, Volume 9, Issue 9, pp. 989 - 993
Journal Article
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