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Journal Article
Current Protocols in Molecular Biology, ISSN 1934-3639, 2012, Volume Chapter 12, Issue 100, p. Unit 12.15
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 06/2016, Volume 2016, Issue 112
Identifying alleles of genes underlying evolutionary change is essential to understanding how and why evolution occurs. Towards this end, much recent work has... 
Astyanax mexicanus | Cavefish | TALENs | TALEN | Astyanax | Genome editing | Molecular biology | SYSTEM | genome editing | ZEBRAFISH | Molecular Biology | CAVE FISH | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | cavefish | EVOLUTION | MUTATION | GENE DISRUPTION | BLIND CAVEFISH | EFFICIENT | EYE DEGENERATION | Phenotype | Animals | Transcription Activator-Like Effector Nucleases | Genome | Gene Editing | Characidae | Issue 112
Journal Article
Engineering in Life Sciences, ISSN 1618-0240, 05/2016, Volume 16, Issue 4, pp. 330 - 337
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1865, pp. 55 - 65
Targeted genome engineering technologies are revolutionizing the field of functional genomics and have been extensively used in a variety of model organisms,... 
TALEN design | Golden gate cloning | Web tools | Genetic Engineering - methods | RNA, Messenger - biosynthesis | Animals | Microinjections | Xenopus - genetics | Base Sequence | Transcription Activator-Like Effector Nucleases - metabolism | Genome
Journal Article
Journal Article
GENESIS, ISSN 1526-968X, 12/2013, Volume 51, Issue 12, pp. 827 - 834
Gene inactivation is an important tool for correlation of phenotypic and genomic data, allowing researchers to infer normal gene function based on the... 
EFFECTOR NUCLEASES TALENS | MUTAGENESIS | SPECIFICITY | TALENs | HUMAN-CELLS | gene targeting | DEVELOPMENTAL BIOLOGY | gene knockouts | ZINC-FINGER NUCLEASES | ONE-STEP GENERATION | ADAPTIVE IMMUNITY | ENDONUCLEASE | GENETICS & HEREDITY | TARGETED GENE DISRUPTION | zinc finger nucleases | CAS9 | CRISPR/Cas
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 02/2016, Volume 428, Issue 5, pp. 963 - 989
Genome engineering with programmable nucleases depends on cellular responses to a targeted double-strand break (DSB). The first truly targetable reagents were... 
zinc finger nucleases (ZFNs) | genome editing | gene therapy | transcription activator-like effector nucleases (TALENs) | CRISPR-Cas9 | Zinc finger nucleases (ZFNs) | Genome editing | Gene therapy | Transcription activator-like effector nucleases (TALENs) | RESTRICTION-MODIFICATION SYSTEM | CONTROLLING GENE-EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | ZINC-FINGER NUCLEASES | DNA-BINDING SPECIFICITY | OFF-TARGET CLEAVAGE | HOMOLOGY-DIRECTED REPAIR | EFFECTOR NUCLEASES | TRANSCRIPTION FACTOR-IIIA | HEMATOPOIETIC STEM | Genetic Engineering - methods | Recombinant Proteins - metabolism | Gene Targeting - methods | Ribonucleases - genetics | Humans | Recombinant Proteins - genetics | Plants | Mammals | Deoxyribonucleases - metabolism | Ribonucleases - metabolism | Molecular Medicine - methods | Deoxyribonucleases - genetics | Animals | Cell Engineering - methods | Recombination, Genetic | Enzymes | Nucleases | Usage | RNA | Analysis | Genomics | Genetic research | DNA binding proteins | Nucleotide sequencing | Zinc finger proteins | Cells | DNA sequencing | Genomes | Genetic transcription | Medical ethics | Anopheles | Designer nucleases | Homology-directed repair (HDR) | Gene targeting (GT) | Double-strand break (DSB) | Homologous recombination (HR) | Chimeric nucleases | Non-homologous end joining (NHEJ)
Journal Article