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The Journal of Organic Chemistry, ISSN 0022-3263, 10/2018, Volume 83, Issue 20, pp. 12863 - 12868
The structure of notoryne comprises a halogenated 2,2′-bifuranyl moiety along with a terminal cis-enyne unit. In this work, we document the first total... 
LAURENCIA-MAJUSCULA | GLYCOFURANOSIDES | MARINE ALGA | ELATENYNE | ALLYLATED C-GLYCOPYRANOSIDES | CHEMISTRY, ORGANIC | ASYMMETRIC TOTAL-SYNTHESIS | LAUREFURENYNES | EFFICIENT | METATHESIS | PREDICTION
Journal Article
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 12/2016, Volume 22, Issue 52, pp. 18733 - 18736
An efficient and practical total synthesis of aquayamycin has been accomplished. The highly oxidized and stereochemically complex tetracyclic ring system was... 
natural products | aquayamycin | total synthesis | angucycline antibiotics | antitumor antibiotics | ALDEHYDES | CLEAVAGE | CHEMISTRY, MULTIDISCIPLINARY | SAQUAYAMYCINS | STREPTOMYCES | RING | INHIBITORS | DERIVATIVES | EFFICIENT | DEAROMATIZATION | Synthesis | Organic compounds | Sequences | Ketones | Pathways | Antibiotics | Strategy | Coupling
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2018, Volume 59, Issue 14, pp. 1360 - 1362
The first total synthesis of janadolide, a new cyclic polyketide-peptide hybrid possessing a -butyl group, is described. The synthesis of an unsaturated... 
Macrolactamization | Depsipeptide | Total synthesis | OXIDATION | CONSTRUCTION | MARINE CYANOBACTERIUM | CHEMISTRY, ORGANIC | CATALYST | EFFICIENT | DISCOVERY | AZADO
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 11/2017, Volume 82, Issue 21, pp. 11655 - 11658
Journal Article
Organic Letters, ISSN 1523-7060, 02/2011, Volume 13, Issue 3, pp. 502 - 505
Total synthesis of (+)-isatisine A is described based on the application of a silyl-directed Mukaiyama-type [3 + 2]-annulation for the preparation of a fully... 
AMIDATION | CHEMISTRY, ORGANIC | EFFICIENT COPPER CATALYST | ALDEHYDES | ASYMMETRIC HOMOALDOL REACTION | ARYL HALIDES | Isatin - analogs & derivatives | Indole Alkaloids - chemical synthesis | Isatin - chemical synthesis | Stereoisomerism | Molecular Structure | Isatin - chemistry | Indole Alkaloids - chemistry | Isatis - chemistry
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2018, Volume 57, Issue 52, pp. 17161 - 17167
Brasilicardins, bacterial diterpenoid natural products that display highly potent immunosuppressive activity, are promising immunosuppressant drug candidates.... 
brasilicardins | Michael addition | natural products | total synthesis | quaternary stereocenters | SELECTIVE SYNTHESIS | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | UNSATURATED ESTERS | AMIDES | Carbohydrates | Conjugates | Hybrids | Quaternary | Amides | Amino acids | Glycosylation | Pharmacology | Drug development | Immunosuppressive agents | Stereoselectivity | Synthesis | Natural products | Terpenes | Saccharides
Journal Article
Nature Chemistry, ISSN 1755-4330, 01/2012, Volume 4, Issue 1, pp. 21 - 25
Taxanes form a large family of terpenes comprising over 350 members, the most famous of which is Taxol (paclitaxel), a billion-dollar anticancer drug. Here, we... 
ANTITUMOR AGENTS | DITERPENOIDS | TAXOL | RING | BIOSYNTHESIS | DIELS-ALDER REACTION | 1ST TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | STEREOCONTROLLED SYNTHESIS | HIGHLY EFFICIENT | PINENE PATH
Journal Article
Tetrahedron, ISSN 0040-4020, 2010, Volume 66, Issue 43, pp. 8407 - 8419
The total synthesis and determination of the absolute configuration of (+)- and (−)-sundiversifolide have been achieved via intramolecular acylation and... 
Xanthanolides | Sesquiterpene lactones | Natural products | Total synthesis | REAGENT | ACID | ENANTIOSELECTIVE SYNTHESIS | CHEMISTRY, ORGANIC | XANTHIUM-STRUMARIUM | EPOXIDES | XANTHATIN | OLEFINS | INHIBITOR | EFFICIENT | Synthesis | Universities and colleges | Organic compounds | Lactones | Acylation | Tetrahedrons | Synthesis (chemistry)
Journal Article
Organic Letters, ISSN 1523-7060, 01/2018, Volume 20, Issue 1, pp. 119 - 121
A total synthesis of huperzine R was accomplished. Intramolecular cycloaddition of a nitrile oxide and reductive cleavage of the resulting isoxazoline induced... 
CORE | ASYMMETRIC 1,3-DIPOLAR CYCLOADDITION | RING-EXPANSION | AMINES | CONSTRUCTION | EFFICIENT SYNTHESIS | FAWCETTIMINE-TYPE | CHEMISTRY, ORGANIC | LYCOPODIUM ALKALOIDS | AZOMETHINE IMINES | STRATEGIES
Journal Article
Organic Letters, ISSN 1523-7060, 09/2011, Volume 13, Issue 18, pp. 4810 - 4813
A stereocontrolled total synthesis of (+)-lysergic acid (1) is achieved using three metal-catalyzed methodologies for the construction of three key rings.... 
(+/-)-LYSERGIC ACID | LYSERGIC-ACID | EFFICIENT TOTAL-SYNTHESIS | CHLOROPEPTIN-I | RING-CLOSING METATHESIS | ERGOT ALKALOIDS | CHEMISTRY, ORGANIC | FORMAL TOTAL-SYNTHESIS | SUZUKI-MIYAURA REACTION | (&/-)-LYSERGIC ACID | DIRECT ANNULATION | Lysergic Acid - chemical synthesis | Lysergic Acid - chemistry | Stereoisomerism | Molecular Conformation
Journal Article
Organic Letters, ISSN 1523-7060, 06/2015, Volume 17, Issue 12, pp. 2890 - 2893
Journal Article
Journal Article
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 4, pp. 585 - 592
The first asymmetric total syntheses of talienbisflavan A and bis-8,8'-epicatechinylmethane as well as a facile synthesis of bis-8,8'-catechinylmethane has... 
REARRANGEMENT | EFFICIENT CATALYST | GREEN TEA CATECHINS | PHENOLIC ANTIOXIDANTS | CHEMISTRY, ORGANIC | HAFNIUM TRIFLATE | FLAVONOIDS | CAMELLIA-TALIENSIS | FORMALDEHYDE | MARINE NATURAL-PRODUCTS | BENZYL ALCOHOLS | Catechin | Synthesis
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 01/2018, Volume 16, Issue 4, pp. 585 - 592
The first asymmetric total syntheses of talienbisflavan A and bis-8,8'-epicatechinylmethane as well as a facile synthesis of bis-8,8'-catechinylmethane has... 
Journal Article
Synthesis, ISSN 0039-7881, 05/2015, Volume 47, Issue 9, pp. 1348 - 1355
Abstract The protecting-group-free total synthesis of (+)-clavulatriene A has been achieved. Key features of the synthetic strategy include the development of... 
paper | protecting-group-free | total synthesis | absolute configuration | clavulatriene A | ACID | CONVERSION | SQUALENE | CHEMISTRY, ORGANIC | TERPENE SYNTHASES | EFFICIENT | (+)-ALPHA-CYPERONE
Journal Article
Tetrahedron, ISSN 0040-4020, 04/2014, Volume 70, Issue 16, pp. 2616 - 2620
A convergent and stereoselective synthesis of cochliomycin A, a 14-membered resorcyclic acid lactone, based on chiron approach is described. The key reactions... 
Cochliomycin A | Resorcylic acid lactones | Total synthesis | CONCISE | RADICICOL | CHEMISTRY, ORGANIC | DERIVATIVES | EFFICIENT | Synthesis | Chemical tests and reagents | Sugars | Organic compounds | Monosaccharides | Synthesis (chemistry) | Chiron | Olefins | Construction materials | Tetrahedrons | Pools | Lactones | Fragmentation
Journal Article
Synlett, ISSN 0936-5214, 12/2014, Volume 25, Issue 20, pp. 2883 - 2886
Abstract The synthesis of (+)-guaymasol has been achieved from O -methyl chavicol by using a sequence combining a cross-metathesis and an asymmetric... 
letter | natural products | phenols | dihydroxylation | total synthesis | cross-metathesis | COMPLEXES | CHEMISTRY, ORGANIC | OLEFIN METATHESIS | ALKENES | NATURAL-PRODUCT SYNTHESIS | RING-CLOSING METATHESIS | ASYMMETRIC DIHYDROXYLATION | SEQUENCE | EFFICIENT | CATALYSTS | Organic chemistry | Chemical Sciences
Journal Article
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