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1. Full Text Multidrug efflux pumps: Substrate selection in ATP‐binding cassette multidrug efflux pumps – first come, first served?
by Ernst, Robert and Kueppers, Petra and Stindt, Jan and Kuchler, Karl and Schmitt, Lutz
The FEBS journal, ISSN 1742-464X, 02/2010, Volume 277, Issue 3, pp. 540 - 549
multidrug resistance | Pdr5 | TAP | ABCB1 | ATP hydrolysis | kinetic substrate selection | multidrug efflux | transport mechanism | ABC transporter | ligand binding | Transport mechanism | Ligand binding | Multidrug resistance | Kinetic substrate selection | Multidrug efflux | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | ATP-Binding Cassette Transporters - chemistry | Drug Resistance, Multiple - genetics | Models, Biological | ATP-Binding Cassette Transporters - metabolism | Adenosine Triphosphatases - metabolism | Saccharomyces cerevisiae Proteins - physiology | Kinetics | ATP-Binding Cassette Transporters - physiology | Drug Resistance, Multiple - physiology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - physiology | Protein Structure, Tertiary - physiology | Saccharomyces cerevisiae Proteins - chemistry | Hydrolysis | Mycoses | Medical colleges | Drug resistance in microorganisms | Twins | Drug delivery systems | Pharmacology | Drug resistance | Binding sites | Adenosine triphosphatase | Index Medicus
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2. Full Text Practical applications and feasibility of efflux pump inhibitors in the clinic—A vision for applied use
by Lomovskaya, Olga and Bostian, Keith A
Biochemical pharmacology, ISSN 0006-2952, 2006, Volume 71, Issue 7, pp. 910 - 918
Fluoroquinolones | Efflux | RND transporters | Pseudomonas | EPIs | Multidrug resistance | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Gram-Negative Bacteria - drug effects | Cell Wall - drug effects | Drug Resistance, Multiple, Bacterial - physiology | Cell Membrane Permeability - physiology | Cell Membrane Permeability - drug effects | Humans | Membrane Transport Proteins - drug effects | Anti-Bacterial Agents - pharmacology | Gram-Negative Bacteria - metabolism | Cell Wall - physiology | Drug Resistance, Multiple, Bacterial - drug effects | Drug resistance in microorganisms | Technology application | Bacterial infections | Index Medicus
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3. Full Text Fast, Na+/K+ pump driven, steady‐state transcytolemmal water exchange in neuronal tissue: A study of rat brain cortical cultures
by Bai, Ruiliang and Springer, Charles S and Plenz, Dietmar and Basser, Peter J
Magnetic resonance in medicine, ISSN 0740-3194, 06/2018, Volume 79, Issue 6, pp. 3207 - 3217
ouabain | active | Na+/K+ pump | steady‐state | transcytolemmal water exchange | neurons | steady-state | pump | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Biological Transport, Active - drug effects | Cells, Cultured | Rats | Cerebral Cortex - cytology | Rats, Sprague-Dawley | Cerebral Cortex - metabolism | Body Water - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Biological Transport, Active - physiology | Models, Biological | Cell Membrane - metabolism | Neurons - metabolism | Ouabain - pharmacology | Fluorescence | Brain | Neurons | Contrast media | Ouabain | Exchanging | Neuroimaging | Membranes | Nuclear magnetic resonance--NMR | Calcium | Homeostasis | Pathways | Water transport | Efflux | Calcium (intracellular) | Cortex | Excitability | Cell membranes | Na+/K+-exchanging ATPase | Magnetic resonance imaging | Perfusion | Water exchange | Resonance | Kinetics | Cell size | Intracellular | Transport
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4. Full Text Multidrug efflux pumps: structure, function and regulation
by Du, Dijun and Wang-Kan, Xuan and Neuberger, Arthur and van Veen, Hendrik W and Pos, Klaas M and Piddock, Laura J. V and Luisi, Ben F
Nature reviews. Microbiology, ISSN 1740-1526, 09/2018, Volume 16, Issue 9, pp. 523 - 539
Life Sciences & Biomedicine | Microbiology | Science & Technology | Drug resistance in microorganisms | Usage | Bacterial infections | Antibiotics | Escherichia coli | Genetic aspects | Research | Drug therapy | Health aspects | Risk factors | Efflux | Molecular modelling | Pumps | Virulence | Bacteria | Extrusion | Infections | Antimicrobial resistance | Drug resistance | Structure-function relationships
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5. Full Text Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
by Nikaido, Hiroshi and Pagès, Jean-Marie
FEMS microbiology reviews, ISSN 0168-6445, 03/2012, Volume 36, Issue 2, pp. 340 - 363
structure–function relationship | RND family drug transporters | antibiotic resistance | outer membrane permeability | MDR bacteria | bacterial efflux pump | Outer membrane permeability | Bacterial efflux pump | Structure-function relationship | Antibiotic resistance | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Humans | Bacterial Proteins - genetics | Anti-Bacterial Agents - metabolism | Gram-Negative Bacterial Infections - drug therapy | Gram-Negative Bacteria - metabolism | Gram-Negative Bacterial Infections - microbiology | Gram-Negative Bacteria - drug effects | Animals | Membrane Transport Proteins - genetics | Drug Resistance, Multiple, Bacterial | Bacterial Proteins - metabolism | Membrane Transport Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Gram-Negative Bacteria - genetics | Translocation | Efflux | Antibiotics | Pumps | Multidrug resistance | Bacteria | Gram-negative bacteria | Parameter identification | Drug resistance | Antibacterial agents | Transporter | Index Medicus | Data processing | Kinetics | Drug development | selectivity | structure-function relationship
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