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PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0127246
Background Neuroblastoma (NB) is the most common cancer in infancy and most frequent cause of death from extracranial solid tumors in children. Ornithine... 
DIAMINE EXPORTER | CELLS | MULTIDISCIPLINARY SCIENCES | ALPHA-DIFLUOROMETHYLORNITHINE | DOUBLE-BLIND | N-MYC | C-MYC | EFLORNITHINE COMBINATION THERAPY | ORNITHINE-DECARBOXYLASE GENE | CANCER | ONCOGENE ADDICTION | Ornithine Decarboxylase Inhibitors - pharmacokinetics | Recurrence | Ornithine Decarboxylase - metabolism | Ornithine Decarboxylase Inhibitors - adverse effects | Humans | Neuroblastoma - enzymology | Child, Preschool | Eflornithine - pharmacokinetics | Eflornithine - adverse effects | Eflornithine - pharmacology | Infant | Male | Eflornithine - therapeutic use | Ornithine Decarboxylase Inhibitors - pharmacology | Ornithine Decarboxylase Inhibitors - therapeutic use | Female | Safety | Child | Etoposide - adverse effects | Neuroblastoma - genetics | Etoposide - pharmacology | Etoposide - therapeutic use | Treatment Outcome | Neuroblastoma - urine | Polyamines - metabolism | Phenotype | Polyamines - urine | Neuroblastoma - drug therapy | Adolescent | Difluoromethylornithine | Dosage and administration | Genetic aspects | Research | Neuroblastoma | Single nucleotide polymorphisms | Drug therapy | Polyamines | Health aspects | Therapy | Pediatrics | Transcription factors | Toxicity | Colorectal cancer | Clinical trials | Oncology | Biosynthesis | Single-nucleotide polymorphism | Epidemiology | Cancer therapies | Regulatory approval | Cell growth | Cell cycle | Children | Drug dosages | Significance | Medical research | Enzymes | Statistical analysis | Etoposide | Pharmacology | Ornithine decarboxylase | Gene expression | Addictions | Patients | Survival | Loci | Substrates | Children & youth | Medicine | Disease prevention | Chemotherapy | Gene amplification | Hospitals | Addiction | Alleles | Solid tumors | Pharmacokinetics | Ornithine | Tumors | Eflornithine | Cancer
Journal Article
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 21, pp. 9683 - 9692
RNA viruses present an extraordinary threat to human health, given their sudden and unpredictable appearance, the potential for rapid spread among the human... 
DRUG | EFLORNITHINE | REPLICATION | VIROLOGY | ALPHA-DIFLUOROMETHYLORNITHINE | DEPLETION | INFECTION | TRANSLATION | MAMMALIAN-CELLS | RESPIRATORY SYNDROME CORONAVIRUS | SPERMIDINE | Zika Virus Infection - drug therapy | Acetyltransferases - metabolism | Ebolavirus - metabolism | Chikungunya virus - metabolism | Humans | Eflornithine - pharmacology | Ebolavirus - drug effects | Zika Virus Infection - virology | Disease Outbreaks | RNA Viruses - drug effects | Hemorrhagic Fever, Ebola - virology | Hemorrhagic Fever, Ebola - drug therapy | Spermine - analogs & derivatives | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Mice, Inbred C57BL | Chikungunya Fever - drug therapy | Zika Virus - drug effects | Chikungunya Fever - virology | Polyamines - metabolism | Chikungunya virus - drug effects | Animals | Spermine - pharmacology | Mice | Spermine/analogs & derivatives | Virus Replication/drug effects | Hemorrhagic Fever, Ebola/virology | Life Sciences | Zika Virus/drug effects | Immunology | Chikungunya virus/metabolism | Chikungunya Fever/drug therapy | Zika Virus Infection/drug therapy | Ebolavirus/drug effects | Acetyltransferases/metabolism | Chikungunya virus/drug effects | Eflornithine/pharmacology | Spermine/pharmacology | Polyamines/metabolism | Chikungunya Fever/virology | Hemorrhagic Fever, Ebola/drug therapy | Virology | Microbiology and Parasitology | Zika Virus Infection/virology | Ebolavirus/metabolism | Antiviral Agents/pharmacology | RNA Viruses/drug effects
Journal Article
Future Microbiology, ISSN 1746-0913, 09/2011, Volume 6, Issue 9, pp. 1037 - 1047
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 12/2007, Volume 45, Issue 11, pp. 1435 - 1442
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 06/2018, Volume 12, Issue 6, p. e0006504
We conducted a retrospective study on mortality trends and risk factors in 781 naive cases of advanced stage-2 sleeping sickness admitted between 1989 and 2012... 
MULTICENTER | PROTEIN | BRUCEI-GAMBIENSE | GAMBIAN TRYPANOSOMIASIS | EFLORNITHINE COMBINATION THERAPY | SCHEDULE | CEREBROSPINAL-FLUID | PARASITOLOGY | TROPICAL MEDICINE | MELARSOPROL TREATMENT | Multivariate Analysis | Recurrence | Trypanosomiasis, African - drug therapy | Nifurtimox - administration & dosage | Humans | Middle Aged | Melarsoprol - administration & dosage | Male | Melarsoprol - therapeutic use | Eflornithine - therapeutic use | Young Adult | Trypanosoma brucei gambiense - drug effects | Trypanosomiasis, African - epidemiology | Trypanosomiasis, African - mortality | Adult | Female | Trypanocidal Agents - therapeutic use | Retrospective Studies | Drug Therapy, Combination | Eflornithine - administration & dosage | Trypanocidal Agents - administration & dosage | Risk Factors | Treatment Outcome | Hospital Records | Trypanosomiasis, African - parasitology | Democratic Republic of the Congo - epidemiology | Adolescent | Disease Management | Nifurtimox - therapeutic use | Mortality | Analysis | Africa | Congo (Kinshasa) | Epidemiology | Trypanosomiasis | Health aspects | Risk factors | Intravenous administration | Nifurtimox | Medical services | Parasites | Cerebrospinal fluid | Gender | Risks | Proteins | Regression models | Fluids | Ratios | Mathematical models | Trends | African trypanosomiasis | Vector-borne diseases | Evaluation | Computational fluid dynamics | Fluid | Duration | Regression analysis | Risk analysis | Patients | Body fluids | Neurology | Death | Eflornithine
Journal Article
International Journal of Radiation Oncology, Biology, & Physics, ISSN 0360-3016, 01/2001, Volume 49, Issue 1, pp. 71 - 77
Purpose: To report the results of a prospective Phase III trial for patients with newly diagnosed glioblastoma multiforme (GBM), treated with either... 
eflornithine
Journal Article
Carcinogenesis, ISSN 0143-3334, 01/2001, Volume 22, Issue 1, pp. 83 - 88
Targeting specific events associated with tumor development represents a rational approach to chemoprevention as well as therapeutic intervention. In this... 
eflornithine
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