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Biochemical Pharmacology, ISSN 0006-2952, 02/2020, Volume 172, p. 113772
Patients with epidermal growth factor receptor (EGFR)-mutant advanced non-small-cell lung cancer (NSCLC) benefits from EGFR-tyrosine kinase inhibitor (TKI)... 
TFAP2A | EGFR-TKIs | DACT2 | Lung adenocarcinoma | Genetic polymorphism
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2012, Volume 1, Issue 4, pp. 287 - 288
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2018, Volume 36, Issue 26, pp. 2702 - 2709
PurposeIn patients with epidermal growth factor receptor (EGFR) mutation-positive advanced non-small-cell lung cancer (NSCLC), there is an unmet need for... 
GEFITINIB | MULTICENTER | PERMEABILITY | ONCOLOGY | METASTASES | ACQUIRED-RESISTANCE | EGFR-TKIS | TYROSINE KINASE INHIBITOR | OPEN-LABEL | BLOOD-BRAIN-BARRIER
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2013, Volume 2, Issue 1, pp. 58 - 61
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2012, Volume 1, Issue 4, pp. 280 - 282
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2013, Volume 2, Issue 1, pp. 55 - 57
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2013, Volume 2, Issue 1, pp. 50 - 54
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2013, Volume 2, Issue 1, pp. 62 - 63
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 01/2020, Volume 21, Issue 1, pp. 61 - 71
EGFR-TKIs such as erlotinib and gefitinib have been introduced into the first-line treatment for patients having a mutation of deletion in exon 19 or L858R... 
EGFR-TKIs | hypoxia | BMSC | leptin | Lung cancer | IGFBP2 | Index Medicus
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2012, Volume 1, Issue 4, pp. 283 - 286
Journal Article
by Wang J and Wang B and Chu H and Yao Y
OncoTargets and Therapy, ISSN 1178-6930, 06/2016, Volume 2016, Issue Issue 1, pp. 3711 - 3726
Jun Wang, Baocheng Wang, Huili Chu, Yunfeng Yao Department of Oncology, General Hospital, Jinan Command of the People's Liberation Army, Jinan, People's... 
EGFR TKIs | NSCLC | intrinsic resistance
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2020, Volume 186, p. 111888
Targeting L858R/T790M/C797S mutant EGFR is a major challenge in the new-generation EGFR tyrosine kinase inhibitors development for conquering drug resistant... 
EGFR-TKIs | 9-Heterocyclyl substituted 9H-purine | Drug design | C797S | Antiproliferative activity
Journal Article
Molecular cancer, ISSN 1476-4598, 11/2019, Volume 18, Issue 1, pp. 165 - 14
The ATLANTIC trial reported that higher PD-L1 expression in tumors was involved in a higher objective response in patients with EGFR /ALK non-small cell lung... 
Signaling pathways | PD-L1 | EGFR-TKIs resistance | Lung cancer | Immunotherapy
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 02/2020, Volume 59, Issue 2, pp. 179 - 192
The discovery of epidermal growth factor receptor (EGFR) mutations has made EGFR tyrosine kinase inhibitors (EGFR‐TKIs) a milestone in the treatment for... 
mPRα | EGFR mutations | sensitivity | EGFR‐TKIs | lung adenocarcinoma
Journal Article
Chinese Journal of Lung Cancer, ISSN 1009-3419, 2018, Volume 21, Issue 3, pp. 241 - 250
Journal Article
Chinese Journal of New Drugs, ISSN 1003-3734, 01/2014, Volume 23, Issue 2, pp. 235 - 240
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 5/2017, Volume 486, Issue 4, pp. 1027 - 1033
Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide. The majority of HNSCCs overexpress Epidermal Growth Factor Receptor... 
Beclin-1 | EGFR TKIs | autophagy | HNSCC | EGFR
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 10/2018, Volume 80, pp. 375 - 395
In our attempt to develop effective EGFR-TKIs, two series of 1 -pyrazolo[3,4- ]pyrimidine derivatives were designed and synthesized. All the newly synthesized... 
NSCLC | EGFRT790M | EGFR-TKIs | Docking | Anticancer | EGFRWT | 1H-Pyrazolo[3,4-d]pyrimidine | EGFR
Journal Article
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