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Molecular and cellular biology, ISSN 0270-7306, 02/2019, Volume 39, Issue 3
Protein synthesis is linked to cell proliferation, and its deregulation contributes to cancer. Eukaryotic translation initiation factor 1A (eIF1A) plays a key... 
eIF1 | 5′ UTR | eIF1A | 5= UTR | eIF1AX | Rps3 | translation initiation | Rps10 | BIOCHEMISTRY & MOLECULAR BIOLOGY | REINITIATION | CELL BIOLOGY | TISU | MESSENGER-RNAS | 5 ' UTR | MUTATIONS | SEQ
Journal Article
Cold Spring Harbor perspectives in biology, ISSN 1943-0264, 02/2019, Volume 11, Issue 2
The eukaryotic translation pathway has been studied for more than four decades, but the molecular mechanisms that regulate each stage of the pathway are not... 
SITE SELECTION | 40S RIBOSOMAL-SUBUNIT | FACTOR 4G EIF4G | MODULATES AUTOREGULATION | CAP-DEPENDENT TRANSLATION | MESSENGER-RNA RECRUITMENT | INITIATION-FACTORS EIF1 | START CODON RECOGNITION | PROTEIN-SYNTHESIS | GTP HYDROLYSIS | CELL BIOLOGY | Translation | Molecular modelling | Kinetics | Dismantling | Intermediates
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 09/2018, Volume 38, Issue 18
Translation initiation of most mRNAs involves m7G-cap binding, ribosomal scanning, and AUG selection. Initiation from an m7G-cap-proximal AUG can be bypassed... 
Leaky scanning | TISU | EIF4E | Translation initiation | EIF1 | EIF4G1 | eIF1 | eIF4E | eIF4G1 | COMPLEX | 40S RIBOSOMAL-SUBUNIT | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | translation initiation | CELL BIOLOGY | MESSENGER-RNAS | ALLOSTERIC MECHANISM | AUG SELECTION | UPSTREAM AUG | START CODON SELECTION | IN-VIVO | BINDING | leaky scanning
Journal Article
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2018, Volume 115, Issue 18, pp. E4159 - E4168
The eukaryotic 43S preinitiation complex (PIC), bearing initiator methionyl transfer RNA (Met-tRNAi) in a ternary complex (TC) with eukaryotic initiation... 
eIF1 | RECRUITMENT | 40S RIBOSOMAL-SUBUNIT | RECOGNITION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | STEP | RELEASE | CONTEXT | yeast | ELEMENTS | EUKARYOTIC TRANSLATION INITIATION | initiation | translation | ribosome | BINDING
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2018, Volume 115, Issue 18, pp. E4159 - E4168
The eukaryotic 43S preinitiation complex (PIC), bearing initiator methionyl transfer RNA (Met-tRNAi) in a ternary complex (TC) with eukaryotic initiation... 
eIF1 | Translation | Ribosome | Yeast | Initiation | Biological Sciences | initiation | PNAS Plus | translation | ribosome | yeast
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2018, Volume 13, Issue 2, p. e0192648
The efficiency of start codon selection during ribosomal scanning in eukaryotic translation initiation is influenced by the context or flanking nucleotides... 
MESSENGER-RNAS | COMPLEX | 40S RIBOSOMAL-SUBUNIT | RECOGNITION | MECHANISM | SEQUENCES | GENOMES | MULTIDISCIPLINARY SCIENCES | INITIATION-FACTORS EIF1 | CONFORMATION | EIF5-MIMIC PROTEIN | Codon | Messenger RNA | Research | Gene expression | Translation | Laboratories | Translation initiation | Homology | Biochemistry | Genomes | Biology | mRNA | Nucleotides | Leucine | Mammals | Leucine zipper proteins | Proteins | Initiation factors | Fungi | Site selection | Codons
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 11/2017, Volume 45, Issue 20, pp. 11941 - 11953
In the human genome, translation initiation from non-AUG codons plays an important role in various gene regulation programs. However, mechanisms regulating the... 
COMPLEX | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | C-TERMINAL DOMAIN | SELECTION | START CODON RECOGNITION | MAMMALIAN-CELLS | GTP HYDROLYSIS | CAP-INDEPENDENT TRANSLATION | EIF1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 11, pp. E2126 - E2135
Journal Article
Cell Reports, ISSN 2211-1247, 03/2017, Volume 18, Issue 11, pp. 2651 - 2663
Journal Article