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Journal Article
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7334, pp. 404 - 408
Activating AMPK or inactivating calcineurin slows ageing in Caenorhabditis elegans(1,2) and both have been implicated as therapeutic targets for age-related... 
COACTIVATOR CRTC2 | TORC2 | UNFOLDED PROTEIN RESPONSE | CAENORHABDITIS-ELEGANS | PATHWAY | INSULIN-RESISTANCE | ER STRESS | MULTIDISCIPLINARY SCIENCES | KINASE | GENE-REGULATION | C-ELEGANS | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Caenorhabditis elegans Proteins - chemistry | Humans | Caenorhabditis elegans Proteins - metabolism | Trans-Activators - chemistry | Gene Knockdown Techniques | Caenorhabditis elegans - physiology | Calcineurin Inhibitors | HEK293 Cells | Trans-Activators - genetics | Transcription, Genetic | Protein-Serine-Threonine Kinases - metabolism | Cyclic AMP Response Element-Binding Protein - biosynthesis | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Down-Regulation | Transcription Factors - biosynthesis | Longevity - genetics | Transcription Factors - metabolism | Animals | Trans-Activators - deficiency | Aging - physiology | Energy Metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Trans-Activators - metabolism | Enzyme Activation | Caenorhabditis elegans Proteins - genetics | Longevity - physiology | Caenorhabditis elegans - enzymology | Calcineurin - metabolism | Aging - metabolism | Caenorhabditis elegans Proteins - biosynthesis | Physiological aspects | Chemical properties | Protein kinases | Calcineurin | Proteins | Homeostasis | Mutation | Kinases | DNA repair | Metabolic disorders | Binding sites
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 12, p. e52493
Numerous studies have shown that resistance to oxidative stress is crucial to stay healthy and to reduce the adverse effects of aging. Accordingly, nutritional... 
BIFIDOBACTERIUM-LONGUM | AGING PROCESS | LONGEVITY | INFLAMMATORY-BOWEL-DISEASE | PROBE LEVEL | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | RECEPTOR NHR-49 | INDUCED COLITIS | C.-ELEGANS | FREE-RADICALS | Caenorhabditis elegans - microbiology | Reactive Oxygen Species - metabolism | Species Specificity | Humans | Caenorhabditis elegans Proteins - metabolism | Gene Expression Profiling | Caenorhabditis elegans - physiology | Trinitrobenzenesulfonic Acid - adverse effects | Inflammation - metabolism | Colitis - chemically induced | Female | Inflammation - microbiology | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Longevity | Probiotics - pharmacology | HT29 Cells | Transcription Factors - metabolism | Insulin - metabolism | Animals | Colitis - microbiology | Signal Transduction - drug effects | Colitis - metabolism | Receptor, Insulin - metabolism | Lactobacillus - physiology | Mice | Oxidative Stress - drug effects | Forkhead Transcription Factors | Antioxidants | Oxidative stress | Caenorhabditis elegans | Anti-inflammatory drugs | Bacteria | Research | Nematoda | Food | Slopes | Salmonella | Cell culture | Biotechnology | Lactic acid bacteria | Animal models | Hydrogen peroxide | Disease | Biology | Lipopolysaccharides | Oxidation resistance | Rodents | Quality | Older people | Aging | Strains (organisms) | Worms | Cytokines | Food production | Inflammation | Metabolism | Insulin | Fatty acids | Quality of life | Probiotics | Screening | Life span | Insects | Nematodes | Lactic acid | Colitis | Diabetes | Laboratory animals | Viability | Geriatrics | Caenorhabditis elegans Proteins | Reactive Oxygen Species | Oxidative Stress | Signal Transduction | Trinitrobenzenesulfonic Acid | Life Sciences | Receptor, Insulin | Transcription Factors | Lactobacillus
Journal Article
Science, ISSN 0036-8075, 12/2015, Volume 350, Issue 6266, pp. 1375 - 1377
Journal Article
The Journal of cell biology, ISSN 1540-8140, 2006, Volume 173, Issue 6, pp. 949 - 961
Polarized intracellular trafficking in epithelia is critical in development, immunity, and physiology to deliver morphogens, defensins, or ion pumps to the... 
Larvae | Phenotypes | Secretion | Epithelial cells | Animal cuticle | Canals | Epidermis | Cell membranes | Exosomes | Genetic mutation | MDCK CELLS | RECYCLING ENDOSOMES | STEROL-SENSING DOMAIN | TRANS-GOLGI-NETWORK | YEAST V-ATPASE | C-ELEGANS | EXTRACELLULAR-MATRIX | ANCHORED PROTEINS | POLARIZED EPITHELIAL-CELLS | PLASMA-MEMBRANE | CELL BIOLOGY | Protein Structure, Tertiary | Amino Acid Sequence | Vacuolar Proton-Translocating ATPases - genetics | Mutagenesis, Site-Directed | Caenorhabditis elegans - growth & development | Secretory Vesicles - ultrastructure | Caenorhabditis elegans Proteins - chemistry | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Protein Transport - physiology | Hedgehog Proteins | Phenotype | Sequence Alignment | Animals | Caenorhabditis elegans - cytology | Models, Biological | Vacuolar Proton-Translocating ATPases - chemistry | Vacuolar Proton-Translocating ATPases - physiology | Secretory Vesicles - physiology | Trans-Activators - metabolism | Caenorhabditis elegans Proteins - physiology | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Physiological aspects | Caenorhabditis elegans | Research | Adenosine triphosphatase | Caenorhabditis elegans Proteins | Trans-Activators | Biochemistry, Molecular Biology | Secretory Vesicles | Protein Transport | Life Sciences | Molecular biology | Vacuolar Proton-Translocating ATPases
Journal Article
Journal Article
Nature cell biology, ISSN 1465-7392, 05/2013, Volume 15, Issue 5, pp. 491 - 501
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2003, Volume 301, Issue 5638, pp. 1387 - 1391
Both dauer formation (a stage of developmental arrest) and adult life-span in Caenorhabditis elegans are negatively regulated by insulin-like signaling, but... 
Morphogenesis | Yeasts | Receptors | Phenotypes | Endocytosis | HEK293 cells | Internalization | Nematodes | Nematode larvae | Reports | Riddles | YEAST | PATHWAYS | LONGEVITY | MUTANTS | CAENORHABDITIS-ELEGANS | PROTEIN-DEGRADATION | MULTIDISCIPLINARY SCIENCES | SENESCENCE | MACROAUTOPHAGY | SACCHAROMYCES-CEREVISIAE | NEMATODE | Saccharomyces cerevisiae - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Genes, Helminth | Caenorhabditis elegans Proteins - metabolism | Recombinant Fusion Proteins - metabolism | RNA Interference | Receptor, Insulin - genetics | Genes, Fungal | Phagosomes - ultrastructure | Autophagy - genetics | Vesicular Transport Proteins | Beclin-1 | Proteins - physiology | Saccharomyces cerevisiae - physiology | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Signal Transduction | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Longevity | Membrane Proteins | Proteins - genetics | Caenorhabditis elegans - ultrastructure | Phenotype | Animals | Apoptosis Regulatory Proteins | Receptor, Insulin - metabolism | Caenorhabditis elegans Proteins - physiology | Mutation | Proteins - chemistry | Caenorhabditis elegans Proteins - genetics | Physiological aspects | Caenorhabditis elegans | Developmental genetics | Genetic aspects | Research | Microorganisms | Genes | Cells
Journal Article
Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 4, pp. 451 - 465
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 338, Issue 6106, pp. 540 - 543
Many biological functions are conserved, but the extent to which conservation applies to integrative behaviors is unknown. Vasopressin and oxytocin... 
Mating behavior | Receptors | Spermatozoa | HEK293 cells | Neurons | REPORTS | Male animals | Reporter genes | Neuropeptides | Vulva | Behavioral neuroscience | MALE MATING-BEHAVIOR | OXYTOCIN | C-ELEGANS | CAENORHABDITIS-ELEGANS | MULTIDISCIPLINARY SCIENCES | Oxytocin - pharmacology | Caenorhabditis elegans Proteins - chemistry | Humans | Male | Vasopressins - chemistry | Neuropeptides - physiology | Receptors, G-Protein-Coupled - agonists | Sexual Behavior, Animal - physiology | Caenorhabditis elegans - physiology | Reproduction | Caenorhabditis elegans Proteins - agonists | Neuropeptides - pharmacology | Neuropeptides - genetics | Oxytocin - chemistry | CHO Cells | Receptors, G-Protein-Coupled - physiology | Amino Acid Sequence | Cricetinae | Caenorhabditis elegans - genetics | Oxytocin - physiology | Vasopressins - genetics | Vasopressins - pharmacology | Biological Evolution | Animals | Oxytocin - genetics | Caenorhabditis elegans Proteins - physiology | Receptors, G-Protein-Coupled - genetics | Vasopressins - physiology | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans Proteins - pharmacology | Neuropeptides - chemistry | Physiological aspects | Oxytocin | Health aspects | Vasopressin | Animal reproduction | Neurosciences | Hormones | Peptides | Learning | Associative | Evolutionary | Sheep | Mammals | Invertebrates | Bonding | Worms
Journal Article