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Cellular Physiology and Biochemistry, ISSN 1015-8987, 07/2017, Volume 42, Issue 4, pp. 1366 - 1376
Background/Aims: Istaroxime is a validated inotropic Na+/K+ ATPase inhibitor currently in development for the treatment of various cardiac conditions. Recent... 
DU-145 prostate cancer cells | Orai1 | SOCE | FAK | Istaroxime | Migration | ELEVATED ORAI1 | OPERATED CA2+ ENTRY | PHYSIOLOGY | MEMBRANE ANDROGEN RECEPTORS | PRO-APOPTOTIC RESPONSES | CELL BIOLOGY | IN-VITRO | NA+/K+ ATPASE INHIBITOR | ACTIN REORGANIZATION | BREAST-TUMOR CELLS | RHABDOMYOSARCOMA CELLS | FOCAL ADHESION KINASE | Focal Adhesion Kinase 1 - genetics | Epithelial Cells - metabolism | Calcium Channels - metabolism | Calcium - metabolism | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Male | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Prostate - metabolism | Stromal Interaction Molecule 1 - genetics | Prostate - pathology | Fura-2 - chemistry | Prostate - drug effects | Etiocholanolone - pharmacology | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Calcium Channels - genetics | Focal Adhesion Kinase 1 - metabolism | ORAI1 Protein - metabolism | Fluorescent Dyes - chemistry | ORAI1 Protein - genetics | Signal Transduction | Etiocholanolone - analogs & derivatives | Epithelial Cells - pathology | Sodium Channel Blockers - pharmacology | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Cell Movement - drug effects | Stromal Interaction Molecule 1 - metabolism | ORAI1 Protein - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Focal Adhesion Kinase 1 - antagonists & inhibitors | Stromal Interaction Molecule 1 - antagonists & inhibitors
Journal Article
Cell Calcium, ISSN 0143-4160, 09/2018, Volume 74, pp. 160 - 167
Cancer is a major cause of death. The diversity of cancer types and the propensity of cancers to acquire resistance to therapies, including new molecularly... 
STIM | Calcium | ORAI | Cancer | ELEVATED ORAI1 | MIGRATION | OPERATED CA2+ ENTRY | ACTIVATION | PROLIFERATION | CELL-CYCLE PROGRESSION | CELL BIOLOGY | BREAST-CANCER | CALCIUM-ENTRY | MOLECULE 2 STIM2 | EXPRESSION | Development and progression | Cell death | Prostate cancer | Estrogen
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 09/2015, Volume 22, Issue 9, pp. 1402 - 1412
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