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Journal Article
Current Directions in Psychological Science, ISSN 0963-7214, 4/2018, Volume 27, Issue 2, pp. 85 - 90
Social connection, the pleasurable, subjective experience of feeling close to and bonded with other people, is critical for well-being and continued social... 
attachment | social reward | social affiliation | endogenous opioids | social bonding | SYSTEM | DEPRESSION | NEUROSCIENCE | HUMANS | AFFILIATION | MECHANISMS | RESPONSES | PSYCHOLOGY, MULTIDISCIPLINARY | ATTACHMENTS | PHYSICAL WARMTH | AGONIST
Journal Article
Journal Article
BRAIN RESEARCH, ISSN 0006-8993, 04/2013, Volume 1506, pp. 58 - 63
Endogenous opioids have been implicated in compound-induced antinociception, and our group previously suggested that xylazine induces peripheral... 
PERIAQUEDUCTAL GRAY | RAT | OPIATE RECEPTOR | Xylazine | Endogenous opioid | MECHANISMS | NEUROSCIENCES | alpha-adrenoceptor | DRUGS | SYSTEMS | MICE | Central antinociception | ROSTRAL VENTROMEDIAL MEDULLA | BRAIN | ANALGESIA
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2013, Volume 21, Issue 21, pp. 6405 - 6413
Journal Article
Nature, ISSN 0028-0836, 08/2016, Volume 537, Issue 7619, pp. 185 - 190
Journal Article
DRUG AND ALCOHOL DEPENDENCE, ISSN 0376-8716, 03/2012, Volume 121, Issue 3, pp. 173 - 180
Mu-opioid receptors (MOR) are the therapeutic target for opiate analgesic drugs and also mediate many of the side-effects and addiction liability of these... 
PSYCHIATRY | Morphine | RGS proteins | SUBSTANCE ABUSE | C6 CELLS | MESSENGER-RNA | SMALL-MOLECULE INHIBITORS | ADENYLYL-CYCLASE | CHOLINERGIC INTERNEURONS | N-TERMINAL DOMAIN | 3RD-INTRACELLULAR LOOP | DIFFERENTIAL MODULATION | ACUTE TOLERANCE | G-proteins | ENDOGENOUS REGULATOR | Mu-opioid receptors
Journal Article
The Clinical Journal of Pain, ISSN 0749-8047, 07/2002, Volume 18, Issue 4 Suppl, pp. S3 - S13
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2006, Volume 97, Issue 1, pp. 292 - 301
The diversity of peptide ligands for a particular receptor may provide a greater dynamic range of functional responses, while maintaining selectivity in... 
κ‐opioid receptors | endogenous kappa ligand | big dynorphin | Endogenous kappa ligand | κ-opioid receptors | Big dynorphin | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRODYNORPHIN MESSENGER-RNA | SPINAL-CORD | STRIATONIGRAL DYNORPHIN | GUINEA-PIG | NOCICEPTIVE BEHAVIOR | NEUROSCIENCES | NEUROPATHIC PAIN | AMINO-ACID-SEQUENCE | kappa-opioid receptors | RAT-BRAIN | SUBSTANCE-P PATHWAYS | OPIATE RECEPTORS | Receptors, Opioid, delta - metabolism | Endorphins - chemistry | Central Nervous System - metabolism | Neural Pathways - drug effects | Dynorphins - genetics | Endorphins - cerebrospinal fluid | Humans | Dynorphins - chemistry | Pain - metabolism | Pain - genetics | Radioimmunoassay | Neurons - metabolism | Radioligand Assay | Neurons - drug effects | Receptors, Opioid - metabolism | Endorphins - genetics | Binding, Competitive - physiology | Receptors, Opioid, mu - drug effects | Receptors, Opioid, mu - metabolism | Receptors, Opioid, kappa - metabolism | Receptors, Opioid, delta - drug effects | Mice, Knockout | Binding, Competitive - drug effects | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Receptors, Opioid, kappa - drug effects | Animals | Cerebrospinal Fluid - metabolism | Pain - physiopathology | Central Nervous System - drug effects | Neural Pathways - metabolism | Ligands | Dynorphins - cerebrospinal fluid | Mice | Receptors, Opioid - drug effects | Binding, Competitive | Neurons | Receptors, Opioid, delta | Cerebrospinal Fluid | Biochemistry, Molecular Biology | Receptors, Opioid, mu | Dynorphins | Neural Pathways | Receptors, Opioid | Life Sciences | Pain | Central Nervous System | Guanosine 5'-O-(3-Thiotriphosphate) | Receptors, Opioid, kappa | Endorphins | Molecular biology
Journal Article
Clinical Obstetrics and Gynecology, ISSN 0009-9201, 03/2019, Volume 62, Issue 1, pp. 3 - 10
The endogenous opioid system is comprised of a wide array of receptors and ligands that are present throughout the central and peripheral nervous system, the... 
opioid therapy | endogenous peptides | endogenous opioids | chronic opioid use | opioid dependence | opioid addiction | REWARD | OBSTETRICS & GYNECOLOGY | CORTICOTROPIN-RELEASING-FACTOR | PAIN | RECEPTOR AVAILABILITY | DYSREGULATION | STRESS | ASSOCIATION | Physiological aspects | Complications and side effects | Receptors | Dosage and administration | Health aspects | Opioids
Journal Article