X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (175) 175
animals (165) 165
neurosciences (121) 121
humans (120) 120
alzheimer's disease (101) 101
endogenous tau (92) 92
alzheimers-disease (87) 87
tau proteins - metabolism (70) 70
tau (65) 65
analysis (59) 59
male (59) 59
mice (58) 58
female (56) 56
research (56) 56
proteins (55) 55
phosphorylation (47) 47
brain (46) 46
biochemistry & molecular biology (45) 45
mouse model (44) 44
alzheimer disease - metabolism (43) 43
neurodegeneration (42) 42
physiology (41) 41
biology (39) 39
economics (39) 39
neurons (39) 39
transgenic mice (36) 36
cell biology (35) 35
rats (35) 35
studies (35) 35
neurofibrillary tangles (33) 33
neurodegenerative diseases (32) 32
tau protein (31) 31
brain - metabolism (30) 30
article (29) 29
endogenous compound (29) 29
gene expression (29) 29
mental disorders (29) 29
protein (29) 29
in-vivo (28) 28
tau proteins - genetics (28) 28
amyloid-beta (27) 27
amyloid beta-peptides - metabolism (26) 26
pathology (26) 26
clinical neurology (25) 25
endogenous growth (25) 25
mice, transgenic (25) 25
disease models, animal (24) 24
neurons - metabolism (24) 24
paired helical filaments (24) 24
physiological aspects (24) 24
review (24) 24
expression (23) 23
health aspects (23) 23
model (23) 23
research article (23) 23
alzheimers disease (22) 22
endogenous-tau (22) 22
neurology (22) 22
alzheimer disease - pathology (21) 21
alzheimer’s disease (21) 21
multidisciplinary sciences (21) 21
nervous system (21) 21
cells, cultured (20) 20
economic growth models (20) 20
in-vitro (20) 20
pregnancy (20) 20
a-beta (19) 19
neuroscience (19) 19
biological clocks (18) 18
circadian rhythm (18) 18
economic models (18) 18
endogenous retroviruses (18) 18
middle aged (18) 18
models (18) 18
pharmacology & pharmacy (18) 18
aggregation (17) 17
endogenous ouabain (17) 17
oligomers (17) 17
aged (16) 16
endogenous rhythms (16) 16
genetic aspects (16) 16
mice, inbred c57bl (16) 16
neurons - pathology (16) 16
alzheimer disease (15) 15
amyloid precursor protein (15) 15
brain - pathology (15) 15
business, finance (15) 15
circadian rhythms (15) 15
dementia (15) 15
developmental biology (15) 15
economic growth (15) 15
economic growth rate (15) 15
life sciences (15) 15
nervous system diseases (15) 15
rodents (15) 15
synaptic plasticity (15) 15
tau proteins (15) 15
tauopathies - metabolism (15) 15
aged, 80 and over (14) 14
biophysics (14) 14
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (18) 18
UTL at Downsview - May be requested (4) 4
UofT at Mississauga - Stacks (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Robarts - Stacks (2) 2
Baycrest Hospital - Stacks (1) 1
Earth Sciences (Noranda) - Stacks (1) 1
Providence Healthcare - Stacks (1) 1
Royal Ontario Museum - Stacks (1) 1
Stacks (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
UofT at Scarborough - Withdrawn (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Reviews Neuroscience, ISSN 1471-003X, 01/2016, Volume 17, Issue 1, pp. 5 - 21
Tau is a microtubule-associated protein that has a role in stabilizing neuronal microtubules and thus in promoting axonal outgrowth. Structurally, tau is a... 
ALZHEIMERS-DISEASE | IN-VIVO | PAIRED HELICAL FILAMENTS | NEURONAL CELL-DEATH | INDUCIBLE MOUSE MODELS | MICROTUBULE-ASSOCIATED PROTEIN | ENDOGENOUS-TAU | NEUROSCIENCES | PROGRESSIVE SUPRANUCLEAR PALSY | AMYLOID-BETA OLIGOMERS | TRANSGENIC MICE
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 01/2017, Volume 9, Issue 374, p. eaag0481
Accumulation of hyperphosphorylated tau directly correlates with cognitive decline in Alzheimer's disease and other primary tauopathies. One therapeutic... 
MEDICINE, RESEARCH & EXPERIMENTAL | NEUROFIBRILLARY TANGLES | ENDOGENOUS TAU | ALZHEIMERS-DISEASE | MOUSE MODEL | ANTISENSE OLIGONUCLEOTIDE | NEURODEGENERATION | CEREBROSPINAL-FLUID | PASSIVE-IMMUNIZATION | PROPAGATION | PROGRESSIVE SUPRANUCLEAR PALSY | CELL BIOLOGY
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2017, Volume 142, Issue 5, pp. 734 - 746
In neurodegenerative diseases like Alzheimer's disease (AD), tau is hyperphosphorylated and forms aggregates and neurofibrillary tangles in affected neurons.... 
tau | autophagy | pimozide | Alzheimer's disease | PHOSPHORYLATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMORY IMPAIRMENT | ENDOGENOUS-TAU | NEUROSCIENCES | MTOR | INHIBITION | AMYLOID-BETA | MOUSE MODEL | AMPK | ULK1 | AMP-Activated Protein Kinases - metabolism | Pimozide - therapeutic use | Humans | Mice, Inbred C57BL | Cells, Cultured | Memory Disorders - metabolism | tau Proteins - metabolism | Dopamine Antagonists - therapeutic use | Male | Mice, Transgenic | Autophagy - physiology | Autophagy-Related Protein-1 Homolog - metabolism | Autophagy - drug effects | Pimozide - pharmacology | Memory Disorders - prevention & control | Animals | Dopamine Antagonists - pharmacology | Female | Mice | Mice, Inbred BALB C | HeLa Cells | tau Proteins - antagonists & inhibitors | Proteins | Oligomers | Nervous system diseases | Neurons | Analysis | Pimozide | Adenylic acid | Protein kinases | Target marketing | TOR protein | Phosphorylation | Animal models | Memory | Activation | Kinases | Autophagy | Inhibition | Dopamine D2 receptors | Dopamine | Adenosine monophosphate | Neurodegenerative diseases | AMP | Flux | Caspase | Pharmacology | Rapamycin | Patients | Neurological diseases | Side effects | Neurofibrillary tangles | Aggregates | Tau protein | Protein kinase | Adenosine kinase | Alzheimers disease | Phagocytosis