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Journal Article
Molecular Cancer, ISSN 1476-4598, 08/2011, Volume 10, Issue 1, pp. 99 - 99
Background: Epithelial-mesenchymal transition (EMT) is the key process driving cancer metastasis. Oncogene/self renewal factor BMI-1 has been shown to induce... 
PROTEIN BMI-1 | OVEREXPRESSION | INVASION | ELEVATED EXPRESSION | METASTASIS | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | GENE-EXPRESSION | OVARIAN | SIGNATURE | BREAST | Humans | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Epithelial-Mesenchymal Transition - genetics | Repressor Proteins - antagonists & inhibitors | Gene Knockdown Techniques | Repressor Proteins - physiology | Sarcoma, Endometrial Stromal - pathology | Endometrial Neoplasms - genetics | RNA Interference | Female | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Sarcoma, Endometrial Stromal - metabolism | Neoplasm Invasiveness | RNA, Small Interfering - pharmacology | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Down-Regulation - genetics | Phenotype | Polycomb Repressive Complex 1 | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Cell Line, Tumor | Endometrial Neoplasms - pathology | Sarcoma, Endometrial Stromal - genetics | Cell Proliferation - drug effects | MicroRNAs - genetics | Nuclear Proteins - physiology | MicroRNAs - physiology | MicroRNA | Endometrial cancer | Cancer cells | Stem cells | Physiological aspects | Genetic aspects | Research
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68923
Endometrial cancer is the most commonly diagnosed gynecologic malignancy worldwide; yet the tumor microenvironment, especially the fibroblast cells surrounding... 
TUMOR-STROMA | MIGRATION | TARGET | LUNG-CANCER | METALLOPROTEINASE EXPRESSION | PATHWAY | MULTIDISCIPLINARY SCIENCES | RECEPTOR | STROMAL CELLS | INTERLEUKIN-8 | ENDOTHELIAL GROWTH-FACTOR | Fibroblasts - enzymology | Fibroblasts - secretion | Endometrium - enzymology | Epithelial Cells - drug effects | Humans | Hyperplasia | Endometrium - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Epithelial Cell Adhesion Molecule | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Female | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Endometrial Neoplasms - enzymology | Cell Separation | Cytokines - secretion | Epithelial Cells - pathology | Enzyme Activation - drug effects | Fibroblasts - pathology | Cell Adhesion Molecules - metabolism | Sirolimus - pharmacology | Thy-1 Antigens - metabolism | Endometrial Neoplasms - secretion | MAP Kinase Signaling System - drug effects | Fibroblasts - drug effects | Endometrial Neoplasms - pathology | Cell Proliferation - drug effects | Endometrium - pathology | Viral antibodies | Endometrial cancer | Estrogen | Cancer cells | Antibodies | Comparative analysis | Intermediate filament proteins | Vascular endothelial growth factor | Cancer | Cell culture | Regulators | RANTES | Estrogens | Lung cancer | AKT protein | Smooth muscle | Metastasis | Angiogenesis | Receptors | Cell growth | Fibroblasts | Tumorigenesis | Conditioning | Growth factors | Medical research | Cytokines | Gynecology | MAP kinase | Cultures | Rapamycin | Gene expression | 1-Phosphatidylinositol 3-kinase | Stem cells | Cell proliferation | Media (culture) | Laboratories | Media (isolation) | Interleukin | Malignancy | Tissues | Macrophages | Cell adhesion & migration | CD90 antigen | Pathways | Actin | Rodents | Cell cycle | Endometrium | Interleukin 8 | Muscles | Extracellular signal-regulated kinase | Pharmacology | Tumor cell lines | Obstetrics | Medicine | Signaling | Medical prognosis | Cell lines | Media (differential) | Progesterone | Apoptosis | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37960
Curcumin, the active component of turmeric, has been shown to protect against carcinogenesis and prevent tumor development. However, little is known about its... 
SURVIVAL | GROWTH-FACTOR RECEPTOR | CONSTITUTIVE ACTIVATION | MULTIDISCIPLINARY SCIENCES | STAT3 | TRANSDUCER | INTERLEUKIN-6 | INHIBITOR | SUPPRESSION | EXPRESSION | CARCINOMA | Lung Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Curcumin - pharmacology | Neovascularization, Pathologic | Cyclin B1 - genetics | Lung Neoplasms - pathology | Janus Kinases - metabolism | Small Cell Lung Carcinoma - genetics | Small Cell Lung Carcinoma - metabolism | Cell Movement - drug effects | Small Cell Lung Carcinoma - pathology | Interleukin-6 - pharmacology | RNA Interference | Signal Transduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Matrix Metalloproteinases - metabolism | Cell Cycle - drug effects | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Proteins | Interleukins | Oncology, Experimental | Cell cycle | Lung cancer, Small cell | Development and progression | Mutual fund industry | Metastasis | Research | Vascular endothelial growth factor | Cancer | Cell proliferation | Phosphorylation | Leukocyte migration | Endometrial cancer | Interleukin | Lung cancer | Mental depression | Kinases | Cancer therapies | Carcinogenesis | Cyclin B1 | Interleukin 6 | Angiogenesis | Signal transduction | Carcinogens | Cell growth | Bcl-x protein | Janus kinase | Curcumin | Inhibition | Cell survival | Intercellular adhesion molecule 1 | Small cell lung carcinoma | Invasiveness | Stat3 protein | Pharmacology | siRNA | Survivin | Chemical compounds | Gelatinase A | Signaling | Cell migration | Matrilysin
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3839 - 12
Endometrial cancer (EMCA) is a clinically heterogeneous disease. Previously, we tested the efficacy of Verteporfin (VP) in EMCA cells and observed cytotoxic... 
PROTEIN | THERAPY | BIOMARKER | MULTIDISCIPLINARY SCIENCES | LIGHT | HIPPO PATHWAY | YAP | PROLIFERATION | CANDIDATE ONCOGENE | IDENTIFICATION | CARCINOMA | Endometrial cancer | Cytotoxicity | Data processing | Gene expression | Ribonucleic acid--RNA | Cell adhesion & migration | Signal transduction | Lymphocytes B | Cell lines | Cell adhesion | Cell cycle | Extracellular matrix | Endometrium | Tumors | Cancer
Journal Article
Oncogene, ISSN 0950-9232, 02/2013, Volume 32, Issue 6, pp. 678 - 688
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e16781
Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and posses antitumor activity. Here, we examined... 
CYCLIN-DEPENDENT KINASES | SIGNALING PATHWAYS | INHIBITION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAP KINASES | DEATH | STRESS | TRANSIENT | ESTROGEN-RECEPTOR | Endometrial Neoplasms - enzymology | Apoptosis - drug effects | Humans | Enzyme Activation - drug effects | Flavonoids - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Caspases - biosynthesis | Cell Line, Tumor | Enzyme Induction - drug effects | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Female | Cell Proliferation - drug effects | Flavonoids - pharmacology | Cell Cycle - drug effects | Flavonoids - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cytochrome c | Endometrial cancer | Health aspects | Estrogen | Cancer | Apoptosis | Cell proliferation | Cytochrome | Phosphorylation | Bax protein | Bcl-2 protein | Estrogens | Estrogen receptors | Activation | Kinases | ADP | MAP kinase kinase | Anticancer properties | Cell activation | Cell growth | Antitumor agents | Ribose | Inhibition | Pretreatment | Endometrium | Cyclin-dependent kinases | Extracellular signal-regulated kinase | Caspase | Poly(ADP-ribose) polymerase | MAP kinase | Polymerase | Inhibitors | Cyclin-dependent kinase inhibitor p27
Journal Article