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2014, Methods in molecular biology, ISBN 9781627039680, Volume 1123.
Web Resource
2014, Methods in molecular biology, ISBN 9781627039680, Volume 1123.
Web Resource
PLoS Biology, ISSN 1544-9173, 04/2017, Volume 15, Issue 4, pp. e2001164 - e2001164
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Approximately 170 million people are chronic carriers of hepatitis C virus (HCV). Patients with chronic hepatitis C are currently treated with pegylated... 
Endonuclease
Journal Article
FEBS Journal, ISSN 1742-464X, 12/2009, Volume 276, Issue 23, pp. 7070 - 7082
Journal Article
Journal of China Medical University, ISSN 0258-4646, 01/2011, Volume 40, Issue 1, pp. 8 - 11
Objective To construct siRNA expression vector of ABCE1, which cany green fluorescent protein gene, and transfect the vector into small cell lung cancer cell... 
Endonuclease
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 16, pp. 6492 - 6496
Interstrand cross-links (ICLs) block replication and transcription and thus are highly cytotoxic. In higher eukaryotes, ICLs processing involves the Fanconi... 
Enzymes | Cell growth | Fanconi anemia | Genetic vectors | DNA damage | DNA | Homologous recombination | Cell cycle | DNA repair | Chromosome aberrations | Mitomycin C | Endonuclease | Cisplatin | STRUCTURE-SPECIFIC ENDONUCLEASE | mitomycin C | MONOUBIQUITINATED FANCD2 | STRAND BREAK REPAIR | MULTIDISCIPLINARY SCIENCES | STRUCTURE-SPECIFIC NUCLEASES | endonuclease | HOLLIDAY JUNCTION RESOLVASE | GENE | VERTEBRATE CELLS | ERCC1/XPF ENDONUCLEASE | HOMOLOGOUS RECOMBINATION | cisplatin | DNA-REPAIR | Endonucleases - genetics | Recombination, Genetic - physiology | Fanconi Anemia Complementation Group D2 Protein - genetics | Recombinases - genetics | Chromatids - genetics | Cross-Linking Reagents - pharmacology | DNA Repair - physiology | Multiprotein Complexes - genetics | Endonucleases - metabolism | Chromatids - metabolism | Multiprotein Complexes - metabolism | Ubiquitination - drug effects | Cell Death - genetics | Chromosome Aberrations - drug effects | DNA Damage - physiology | Cell Death - drug effects | Ubiquitination - physiology | DNA Damage - drug effects | Cell Line | DNA Repair - drug effects | Recombinases - metabolism | Zinc Fingers | Animals | Fanconi Anemia Complementation Group D2 Protein - metabolism | Chickens | Cell Proliferation - drug effects | Recombination, Genetic - drug effects | Nucleases | Crosslinked polymers | Physiological aspects | Development and progression | Genetic aspects | Research | Health aspects | Protein binding | Fanconi's anemia | Proteins | Eukaryotes | Anemia | Chromosomes | Binding sites | Apoptosis | Index Medicus | Biological Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 07/2017, Volume 67, Issue 1, pp. 117 - 127.e5
Journal Article
NATURE BIOTECHNOLOGY, ISSN 1087-0156, 06/2014, Volume 32, Issue 6, pp. 569 - 569
Monomeric CRISPR-Cas9 nucleases are widely used for targeted genome editing but can induce unwanted off-target mutations with high frequencies. Here we... 
ACTIVATION | ENDONUCLEASE | TALENS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CAS9
Journal Article
Journal Article