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by Liang, WC and Ren, JL and Yu, QX and Li, J and Ng, TK and Chu, WK and Qin, YJ and Chu, KO and Schally, AV and Pang, CP and Chan, SO
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2020, Volume 117, Issue 11, pp. 6067 - 6074
Journal Article
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, ISSN 1080-7683, 03/2020, Volume 36, Issue 2, pp. 75 - 87
Background: Iontophoresis is a noninvasive delivery system designed to overcome barriers to ocular penetration of topical ophthalmic medications by employing a... 
TRANSEPITHELIAL IONTOPHORESIS | ENDOTOXIN-INDUCED-UVEITIS | COLLAGEN CROSS-LINKING | OCULAR IONTOPHORESIS | EGP-437 | IODIDE IONTOPHORESIS | CARRIER SYSTEMS | EyeGate II system | TRANSSCLERAL IONTOPHORESIS | OPHTHALMOLOGY | EMULSION 0.05-PERCENT | PHARMACOLOGY & PHARMACY | DEXAMETHASONE PHOSPHATE | iontophoresis | 2-PERCENT LIDOCAINE
Journal Article
Journal of Drug Delivery Science and Technology, ISSN 1773-2247, 02/2020, Volume 55, p. 101389
Journal Article
Ocular Immunology and Inflammation, ISSN 0927-3948, 02/2020, Volume 28, Issue 2, pp. 240 - 248
...) inhibitor, on endotoxin-induced uveitis (EIU) in rats. Methods: EIU was induced by a subcutaneous injection of lipopolysaccharide (LPS) in Lewis rats... 
peritoneal exudate cells (PEC) | Dexamethasone | endotoxin-induced uveitis (EIU) | NF-κB inhibitor | DHMEQ | APOPTOSIS | ACTIVATION | SMALL-MOLECULE INHIBITOR | NF-kappa B inhibitor | TUMOR-NECROSIS-FACTOR | PIGMENT EPITHELIAL-CELLS | INFLAMMATION | GENE-EXPRESSION | OPHTHALMOLOGY | BACTERIAL-ENDOTOXIN | EPOXYQUINOMICIN
Journal Article
Journal of Drug Delivery Science and Technology, ISSN 1773-2247, 12/2019, Volume 54, p. 101341
.... We tested the hypothesis that a cluster bomb releasing corneal-penetrating bomblet of drug assembles would increases drug bioavailability and reduce the administration frequency of corticosteroids in uveitis treatment... 
Eye drops | Drug delivery | Loteprednol etabonate | Corneal penetration | Anterior uveitis | CYCLODEXTRIN COMPLEXES | STEROIDS | PHARMACOKINETICS | DRUG-DELIVERY | PHARMACOLOGY & PHARMACY | ENDOTOXIN-INDUCED UVEITIS
Journal Article
by Yang, L and Qiu, YG and Liu, JY and Lin, R and Yu, P and Fu, XY and Hao, BT and Lei, B
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, ISSN 1080-7683, 05/2019, Volume 35, Issue 4, pp. 235 - 244
Purpose: To investigate retinal gene expression of tetramethylpyrazine (TMP) eye drop-treated endotoxin-induced uveitis (EIU... 
CELLS | COMPLEMENT | RNA | transcriptome | MODEL | interferon | tetramethylpyrazine | retina | endotoxin-induced uveitis | OPHTHALMOLOGY | PHARMACOLOGY & PHARMACY | AGENTS | GRANZYME-B
Journal Article
Microorganisms (Basel), ISSN 2076-2607, 2019, Volume 7, Issue 11, p. 537
...: keratitis, conjunctivitis, uveitis, and endophthalmitis. Interestingly, the PMN response from the host seems to be necessary for pathogen clearance in ocular disease... 
polymorphonuclear leukocytes | BACILLUS-CEREUS ENDOPHTHALMITIS | bacteria | STAPHYLOCOCCUS-AUREUS INFECTION | STREPTOCOCCUS-PNEUMONIAE CAPSULE | MICROBIAL KERATITIS | ALPHA-TOXIN | VIRULENCE FACTOR | MICROBIOLOGY | conjunctivitis | uveitis | ENDOTOXIN-INDUCED UVEITIS | keratitis | innate immunity | PSEUDOMONAS-AERUGINOSA | LIVER-ABSCESS | endophthalmitis | neutrophils | KLEBSIELLA-PNEUMONIAE
Journal Article
Journal of veterinary medical science, ISSN 0916-7250, 2019, Volume 81, Issue 4, pp. 573 - 576
We investigated the effects of tyrosol (Tyr) on anterior chamber paracentesis (ACP)–induced anterior uveitis in beagle dogs, as determined by protein and prostaglandin E2... 
blood–aqueous barrier | anterior chamber paracentesis | tyrosol | anterior uveitis | dog | OCULAR INFLAMMATION | MANAGEMENT | AQUEOUS-HUMOR | blood-aqueous barrier | BARRIER BREAKDOWN | ENDOTOXIN-INDUCED UVEITIS | INHIBITION | VETERINARY SCIENCES | PROSTAGLANDIN | STRESS | ANTIINFLAMMATORY DRUGS | Proteins | Dogs | Uveitis | Phenols | Prostaglandin E2 | Anterior chamber | Pretreatment | Phenolic compounds | Tyrosol | Clinical Pathology
Journal Article
by Cheng, ZX and Yang, Y and Duan, F and Lou, BS and Zeng, JT and Huang, YQ and Luo, Y and Lin, XF
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 03/2019, Volume 10, p. 389
.... However, its role in endotoxin-induced uveitis (EIU) remains unknown. This study aimed to investigate the role of Notch1 signaling on retinal microglia polarization and inflammation in the cultured retinal microglial cells and EIU rat model... 
ACTIVATION | retinal microglia | ISCHEMIA | RECEPTOR | DEATH | Notch1 signaling | IMMUNOLOGY | CYTOKINE EXPRESSION | RESPONSES | inflammation | PATHWAY | endotoxin-induced uveitis | DISEASE | UVEITIS | polarization | CELL | DAPT | Care and treatment | Endotoxins | Uveitis | Cellular signal transduction | Inflammation | Research | Health aspects
Journal Article
Journal Article
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 01/2020, Volume 10
.... We performed single-eye mRNA-sequencing on microglia at different timepoints following a single inflammatory stimulus to characterise their transcriptome during and after resolution of endotoxin-induced uveitis (EIU... 
lipopolysaccharide (LPS) | CELLS | ACTIVATION | transcriptome | MOUSE | mRNA-Seq | PHENOTYPE | IMMUNOLOGY | uveitis | ENDOTOXIN-INDUCED UVEITIS | resolution | heterogeneity | CIRCULATING MONOCYTES | GENE | retina | MONOCYTE-DERIVED MACROPHAGES | FATE MAPPING REVEALS | microglia | EXPRESSION | Tamoxifen | Inflammation | Messenger RNA
Journal Article