X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (279820) 279820
Publication (35308) 35308
Newsletter (11528) 11528
Newspaper Article (8279) 8279
Patent (7319) 7319
Book Review (2098) 2098
Book Chapter (1646) 1646
Book / eBook (989) 989
Magazine Article (393) 393
Conference Proceeding (360) 360
Dissertation (234) 234
Government Document (205) 205
Trade Publication Article (133) 133
Transcript (68) 68
Web Resource (59) 59
Data Set (53) 53
Reference (53) 53
Paper (32) 32
Report (25) 25
Journal / eJournal (6) 6
Streaming Video (3) 3
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (126500) 126500
animals (121560) 121560
index medicus (108266) 108266
enzymes (90062) 90062
enzyme inhibitors - pharmacology (66718) 66718
male (65269) 65269
biochemistry & molecular biology (46188) 46188
rats (45676) 45676
female (44262) 44262
mice (41776) 41776
research (37541) 37541
proteins (36920) 36920
pharmacology & pharmacy (28043) 28043
cell biology (26523) 26523
expression (25753) 25753
research article (24735) 24735
biochemistry (23716) 23716
analysis (22970) 22970
apoptosis (22854) 22854
phosphorylation (22842) 22842
physiological aspects (22805) 22805
cells, cultured (22437) 22437
enzyme activation (21167) 21167
multidisciplinary sciences (20774) 20774
enzyme-linked immunosorbent assay (20704) 20704
gene expression (19812) 19812
medicine (19772) 19772
kinetics (19689) 19689
cancer (19555) 19555
middle aged (19448) 19448
oncology (19384) 19384
dose-response relationship, drug (17975) 17975
signal transduction (17915) 17915
activation (17838) 17838
adult (16952) 16952
article (16908) 16908
enzyme inhibitors (16835) 16835
microbiology (16693) 16693
inhibition (16318) 16318
metabolism (16176) 16176
cell line (16056) 16056
physiology (15525) 15525
science (15253) 15253
enzyme activation - drug effects (15159) 15159
health aspects (15110) 15110
cells (14805) 14805
neurosciences (14780) 14780
aged (14664) 14664
cell line, tumor (14652) 14652
chemistry (14434) 14434
rats, sprague-dawley (14350) 14350
kinases (14133) 14133
time factors (14071) 14071
oxidative stress (14017) 14017
biology (13424) 13424
rodents (13336) 13336
genetic aspects (13152) 13152
molecular sequence data (13072) 13072
inflammation (12687) 12687
amino acid sequence (12376) 12376
inhibitors (12191) 12191
immunology (11791) 11791
enzyme inhibitors - chemistry (11774) 11774
mutation (11725) 11725
studies (11451) 11451
blotting, western (11293) 11293
in-vitro (11143) 11143
angiotensin-converting enzyme inhibitors - therapeutic use (11095) 11095
protein binding (10880) 10880
binding sites (10826) 10826
chemistry, medicinal (10779) 10779
care and treatment (10596) 10596
hypertension (10388) 10388
apoptosis - drug effects (10353) 10353
enzymology (10243) 10243
rats, wistar (10159) 10159
signal transduction - drug effects (10097) 10097
nitric oxide (10040) 10040
models, molecular (10002) 10002
peptides (9992) 9992
in vitro techniques (9877) 9877
protein (9593) 9593
gene-expression (9534) 9534
structure-activity relationship (9474) 9474
cardiac & cardiovascular systems (9091) 9091
biophysics (8899) 8899
genes (8831) 8831
peripheral vascular disease (8776) 8776
medicine, research & experimental (8653) 8653
identification (8627) 8627
disease models, animal (8536) 8536
enzyme inhibitors - therapeutic use (8465) 8465
mice, inbred c57bl (8313) 8313
biotechnology & applied microbiology (8300) 8300
toxicology (8284) 8284
endocrinology & metabolism (8250) 8250
substrate specificity (8246) 8246
disease (8144) 8144
binding (8127) 8127
in-vivo (8095) 8095
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (527) 527
UofT at Mississauga - Stacks (82) 82
Chemistry (A D Allen) - Stacks (62) 62
Engineering & Comp. Sci. - Stacks (55) 55
UTL at Downsview - May be requested (50) 50
Collection Dvlpm't (Acquisitions) - Vendor file (49) 49
Online Resources - Online (42) 42
UofT at Scarborough - Stacks (31) 31
Collection Dvlpm't (Acquisitions) - Closed Orders (20) 20
Earth Sciences (Noranda) - Stacks (16) 16
Gerstein Science - Reference (6) 6
Chemistry (A D Allen) - May be requested in 6-10 wks (3) 3
Gerstein Science - Missing (3) 3
UofT at Scarborough - Withdrawn (3) 3
Engineering & Comp. Sci. - May be requested in 6-10 wks (2) 2
Robarts - Stacks (2) 2
Trinity College (John W Graham) - Stacks (2) 2
UofT at Mississauga - Reference (2) 2
UofT at Scarborough - May be requested in 6-10 wks (2) 2
Chemistry (A D Allen) - Reference (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Engineering & Comp. Sci. - Missing (1) 1
Engineering & Comp. Sci. - Not Returned (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Not Returned (1) 1
Gerstein Science - Periodical Stacks (1) 1
Mt Sinai Hospital - Pathology (1) 1
Online (1) 1
Online Resources - Pharmacy (1) 1
Physics - Stacks (1) 1
Royal Ontario Museum - Stacks (1) 1
Scarborough Hospital - Online (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
UofT at Scarborough - Storage (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (305995) 305995
French (2823) 2823
German (1629) 1629
Japanese (1411) 1411
Chinese (1084) 1084
Russian (859) 859
Spanish (475) 475
Korean (326) 326
Portuguese (128) 128
Italian (124) 124
Polish (116) 116
Norwegian (101) 101
Hungarian (81) 81
Czech (70) 70
Turkish (65) 65
Ukrainian (55) 55
Danish (54) 54
Serbian (24) 24
Bulgarian (21) 21
Slovak (19) 19
Croatian (18) 18
Finnish (18) 18
Romanian (17) 17
Swedish (17) 17
Dutch (15) 15
Arabic (14) 14
Slovenian (13) 13
Hebrew (12) 12
Greek (7) 7
Lithuanian (5) 5
Indonesian (4) 4
Persian (4) 4
Icelandic (3) 3
Latvian (3) 3
Afrikaans (2) 2
Bosnian (2) 2
Catalan (1) 1
Estonian (1) 1
Moldavian (1) 1
Ndonga (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biological Chemistry, ISSN 0021-9258, 05/2011, Volume 286, Issue 21, pp. 18633 - 18640
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2018, Volume 61, Issue 3, pp. 1098 - 1117
We initiated our structure activity relationship (SAR) studies for selective ACC1 inhibitors from la as a lead compound. SAR. studies of bicyclic scaffolds... 
CANCER-CELLS | TARGET | CHEMISTRY, MEDICINAL | FATTY-ACID SYNTHESIS | ENZYME | METABOLISM | TUMOR-GROWTH | DERIVATIVES
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2017, Volume 323, pp. 74 - 80
Indoleamine 2,3-dioxygenase 1 (IDO1) plays a key role in the immune system by regulating tryptophan levels and T cell differentiation. Several tumor types... 
IDO inhibitors | Clinical trials | Aryl Hydrocarbon Receptor | AHR agonists | IDO1 | Cancer | DENDRITIC CELLS | KYNURENINE PATHWAY | AH RECEPTOR | TRYPTOPHAN CATABOLISM | INTERFERON-GAMMA | COLORECTAL-CANCER | THERAPEUTIC TARGET | DISEASE | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | T-CELLS | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Cytochrome P-450 CYP1A1 - genetics | Basic Helix-Loop-Helix Transcription Factors - agonists | Basic Helix-Loop-Helix Transcription Factors - genetics | Risk Assessment | Humans | Enzyme Inhibitors - pharmacology | Receptors, Aryl Hydrocarbon - genetics | Enzyme Induction | Hep G2 Cells | Receptors, Aryl Hydrocarbon - agonists | Animals | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Enzyme Inhibitors - toxicity | Receptors, Aryl Hydrocarbon - metabolism | Ligands | Transcription, Genetic | Mice | Cytochrome P-450 CYP1A1 - biosynthesis | Genes, Reporter | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Physiological aspects | Tryptophan | T cells | Xenobiotics | Cells | Herbicides | Medical colleges | Dioxin | Cytochrome P-450 | Index Medicus | DIOXIN | KYNURENINE | TRYPTOPHAN | NEOPLASMS | CLINICAL TRIALS | DMSO | SUBSTRATES | QUINOLINES | 60 APPLIED LIFE SCIENCES | LUCIFERASE | MEDICAL SURVEILLANCE | ENZYME ACTIVITY | XENOBIOTICS | HYDROXY COMPOUNDS | LIGANDS | METABOLISM | DRUGS | GENES | PHOSPHATES | CELL DIFFERENTIATION | MICE | RECEPTORS | BEARS
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2017, Volume 27, Issue 16, pp. 3897 - 3904
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0166725
Journal Article