X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (43785) 43785
Publication (3303) 3303
Patent (1013) 1013
Book Review (356) 356
Book Chapter (312) 312
Dissertation (101) 101
Conference Proceeding (81) 81
Book / eBook (47) 47
Web Resource (29) 29
Magazine Article (20) 20
Data Set (15) 15
Streaming Video (15) 15
Government Document (4) 4
Newsletter (3) 3
Paper (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cytochrome p-450 enzyme system - metabolism (27253) 27253
animals (25810) 25810
humans (17521) 17521
male (16750) 16750
rats (13688) 13688
cytochrome p-450 enzyme system - genetics (12707) 12707
pharmacology & pharmacy (9071) 9071
index medicus (9000) 9000
female (8579) 8579
microsomes, liver - enzymology (7563) 7563
biochemistry & molecular biology (7019) 7019
metabolism (5261) 5261
liver - enzymology (5141) 5141
cytochrome p450 (4887) 4887
kinetics (4870) 4870
mice (4869) 4869
cytochrome p-450 enzyme system - biosynthesis (4833) 4833
microsomes, liver - metabolism (4802) 4802
toxicology (4330) 4330
enzymes (4054) 4054
microsomes, liver - drug effects (3960) 3960
cytochrome p-450 (3891) 3891
liver - drug effects (3783) 3783
mixed function oxygenases - metabolism (3670) 3670
expression (3638) 3638
liver - metabolism (3627) 3627
oxidation-reduction (3589) 3589
molecular sequence data (3525) 3525
hydroxylation (3509) 3509
cytochrome p-450 enzyme system - chemistry (3446) 3446
cytochrome p-450 enzyme inhibitors (3298) 3298
in vitro techniques (3176) 3176
rats, inbred strains (3160) 3160
adult (3090) 3090
biotransformation (3025) 3025
cytochrome p-450 cyp3a (3016) 3016
aryl hydrocarbon hydroxylases (2888) 2888
liver (2841) 2841
phenobarbital - pharmacology (2760) 2760
amino acid sequence (2646) 2646
enzyme induction - drug effects (2616) 2616
rats, sprague-dawley (2544) 2544
base sequence (2532) 2532
middle aged (2515) 2515
drug interactions (2485) 2485
enzyme induction (2423) 2423
substrate specificity (2377) 2377
induction (2370) 2370
isoenzymes - metabolism (2301) 2301
cells, cultured (2223) 2223
physiological aspects (2156) 2156
dose-response relationship, drug (2088) 2088
analysis (2074) 2074
pharmacokinetics (2027) 2027
identification (2012) 2012
microbiology (1970) 1970
cytochrome p-450 enzyme system - analysis (1893) 1893
gene expression (1890) 1890
rabbits (1888) 1888
research (1821) 1821
time factors (1807) 1807
chemistry (1757) 1757
cytochrome p-450 enzyme system (1736) 1736
chromatography, high pressure liquid (1707) 1707
in-vitro (1694) 1694
mixed function oxygenases - genetics (1665) 1665
cytochrome p-450 enzyme system - physiology (1607) 1607
rats, wistar (1607) 1607
biochemistry (1605) 1605
enzyme inhibitors - pharmacology (1594) 1594
genotype (1593) 1593
aged (1585) 1585
inhibition (1581) 1581
genes (1574) 1574
microsomes - enzymology (1565) 1565
oxidoreductases - metabolism (1553) 1553
biophysics (1531) 1531
rat (1507) 1507
mutation (1503) 1503
oxidation (1494) 1494
steroid hydroxylases - metabolism (1477) 1477
rna, messenger - metabolism (1467) 1467
cloning, molecular (1463) 1463
polymorphism, genetic (1443) 1443
binding sites (1410) 1410
catalysis (1395) 1395
pharmaceutical preparations - metabolism (1390) 1390
protein binding (1390) 1390
proteins (1386) 1386
nadph-ferrihemoprotein reductase - metabolism (1373) 1373
oncology (1342) 1342
cytochrome p-450 enzyme system - drug effects (1314) 1314
species specificity (1312) 1312
cytochrome p-450 enzyme system - isolation & purification (1304) 1304
metabolites (1270) 1270
recombinant proteins - metabolism (1250) 1250
microsomes (1239) 1239
biotechnology & applied microbiology (1232) 1232
phenotype (1201) 1201
models, molecular (1200) 1200
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (33) 33
Online Resources - Online (30) 30
Collection Dvlpm't (Acquisitions) - Vendor file (5) 5
Chemistry (A D Allen) - Stacks (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (1) 1
UTL at Downsview - May be requested (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (42612) 42612
Japanese (1733) 1733
Chinese (945) 945
Russian (805) 805
French (326) 326
German (219) 219
Polish (102) 102
Spanish (68) 68
Italian (24) 24
Danish (18) 18
Norwegian (16) 16
Czech (14) 14
Hungarian (14) 14
Bulgarian (13) 13
Dutch (13) 13
Swedish (12) 12
Ukrainian (10) 10
Finnish (8) 8
Korean (7) 7
Portuguese (5) 5
Hebrew (4) 4
Romanian (3) 3
Slovak (3) 3
Croatian (1) 1
Greek (1) 1
Persian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug Metabolism and Disposition, ISSN 0090-9556, 03/2010, Volume 38, Issue 3, pp. 516 - 525
HepaRG cells possess the unique property to differentiate in vitro and to express various functions of mature hepatocytes, including the major cytochromes P450... 
COCKTAIL | TRANSPORTER | IN-VITRO MODEL | LIVER | LINE | CULTURED HUMAN HEPATOCYTES | PHARMACOLOGY & PHARMACY | INDUCTION | MICROSOMAL-ENZYME INDUCERS | TANDEM MASS-SPECTROMETRY | DRUG-METABOLISM | Phenobarbital - pharmacology | Humans | Cytochrome P-450 Enzyme System - metabolism | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear - biosynthesis | RNA, Messenger - metabolism | Glucuronosyltransferase - genetics | Hepatocytes - cytology | Glutathione Transferase - genetics | Time Factors | Isoenzymes - metabolism | Membrane Transport Proteins - genetics | Enzyme Induction - drug effects | Membrane Transport Proteins - metabolism | Omeprazole - pharmacology | Cell Differentiation | Xenobiotics - metabolism | Cell Culture Techniques | Hepatocytes - drug effects | Drug Evaluation, Preclinical - methods | Reproducibility of Results | Isoenzymes - genetics | Cells, Cultured | Glutathione Transferase - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Gene Expression Regulation - drug effects | Glutathione Transferase - biosynthesis | Membrane Transport Proteins - biosynthesis | Glucuronosyltransferase - metabolism | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Rifampin - pharmacology | Isoenzymes - biosynthesis | Glucuronosyltransferase - biosynthesis | Cell Line, Transformed | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Receptors, Cytoplasmic and Nuclear | Life Sciences | Glutathione Transferase | Xenobiotics | Drug Evaluation, Preclinical | Glucuronosyltransferase | Hépatology and Gastroenterology | Isoenzymes | Gene Expression Regulation | Enzyme Induction | Cytochrome P-450 Enzyme System | Omeprazole | Human health and pathology | Phenobarbital | Hepatocytes | Membrane Transport Proteins | RNA, Messenger | Rifampin
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2012, Volume 134, Issue 45, pp. 18695 - 18704
Journal Article
Current Opinion in Biotechnology, ISSN 0958-1669, 2011, Volume 22, Issue 6, pp. 809 - 817
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 31, pp. 12657 - 12662
Although Apis mellifera, the western honey bee, has long encountered pesticides when foraging in agricultural fields, for two decades it has encountered... 
Honey bees | Insect pests | Pyrethrins | Midgut | Insect pathology | Pesticides | Cytochromes | Metabolism | Insect genetics | Apiculture | Apidae | Transcriptional regulation | Miticide | HYMENOPTERA | transcriptional regulation | MULTIDISCIPLINARY SCIENCES | PYRETHROID RESISTANCE | TOXICITY | CYTOCHROME-P450 GENES | miticide | OVEREXPRESSION | DELTAMETHRIN | SEQUENCE ALIGNMENT | P450 GENES | INSECTICIDES | Gene Expression Regulation, Enzymologic - drug effects | Inactivation, Metabolic | Bees - parasitology | Insecticides - chemistry | Gas Chromatography-Mass Spectrometry | Nitriles - pharmacology | Cytochrome P-450 Enzyme System - metabolism | Molecular Sequence Data | Isoenzymes - chemistry | Phylogeny | Bees - enzymology | Pyrethrins - pharmacology | Acaricides - pharmacokinetics | Cytochrome P-450 Enzyme System - classification | Isoenzymes - metabolism | Coumaphos - pharmacokinetics | Molecular Structure | Host-Parasite Interactions | Pyrethrins - metabolism | Insect Proteins - metabolism | Insecticides - pharmacology | Protein Structure, Tertiary | Amino Acid Sequence | Nitriles - metabolism | Isoenzymes - genetics | Insect Proteins - genetics | Models, Molecular | Varroidae - physiology | Reverse Transcriptase Polymerase Chain Reaction | Pyrethrins - chemistry | Sequence Homology, Amino Acid | Cytochrome P-450 Enzyme System - chemistry | Animals | Insecticides - metabolism | Nitriles - chemistry | Varroidae - drug effects | Cytochrome P-450 Enzyme System - genetics | Protein Binding | Acaricides - toxicity | Acaricides | Physiological aspects | Cytochrome P-450 | Biological Sciences
Journal Article
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, ISSN 0962-8436, 02/2013, Volume 368, Issue 1612, p. 20120431
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 10/2013, Volume 455, Issue 1, pp. 75 - 85
The resistance of mosquitoes to chemical insecticides is threatening vector control programmes worldwide. Cytochrome P450 monooxygenases (CYPs) are known to... 
DENGUE VECTOR | recombinant system | VECTOR AEDES-AEGYPTI | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | insecticide | IN-VITRO METABOLISM | ANOPHELES-GAMBIAE | resistance | mosquito | YEAST | MALARIA VECTOR | cytochrome P450 monooxygenase | metabolism | P450 | pyrethroid | Inactivation, Metabolic | Insecticides - chemistry | NADPH-Ferrihemoprotein Reductase - genetics | Saccharomyces cerevisiae - genetics | Benzoates - metabolism | Cytochrome P-450 Enzyme System - metabolism | Insecticide Resistance - genetics | NADPH-Ferrihemoprotein Reductase - chemistry | Saccharomyces cerevisiae - drug effects | Isoenzymes - chemistry | Pyrethrins - pharmacology | Insect Vectors - drug effects | Isoenzymes - metabolism | Insecticide Resistance - drug effects | Aedes - enzymology | Pyrethrins - metabolism | Insect Proteins - metabolism | Insect Vectors - enzymology | Insecticides - pharmacology | Benzaldehydes - chemistry | Escherichia coli - enzymology | NADPH-Ferrihemoprotein Reductase - metabolism | Oxidation-Reduction | Isoenzymes - genetics | Anopheles - drug effects | Insect Proteins - genetics | Benzaldehydes - pharmacology | Aedes - drug effects | Pyrethrins - chemistry | Anopheles - enzymology | Benzaldehydes - metabolism | Cytochrome P-450 Enzyme System - chemistry | Animals | Genetic Engineering | Insecticides - metabolism | Escherichia coli - genetics | Insect Proteins - chemistry | Cytochrome P-450 Enzyme System - genetics | Saccharomyces cerevisiae - enzymology | Molecular Docking Simulation | AeCPR, Aedes aegypti CPR | 7-OH, 7-hydroxycoumarin | SRS, substrate recognition site | CPR, NADPH-cytochrome P450-reductase | Rt, retention time | Cyt b5, cytochrome b5 | PBAld, 3-phenoxybenzaldehyde | qPCR, quantitative real-time PCR | PBA, 3-phenoxybenzoic acid | PBAlc, 3-phenoxybenzoic alcohol | TFA, trifluoroacetic acid
Journal Article
Journal Article