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Cell, ISSN 0092-8674, 2009, Volume 139, Issue 4, pp. 693 - 706
Inflammation is linked clinically and epidemiologically to cancer, and NF-κB appears to play a causative role, but the mechanisms are poorly understood. We... 
CELLCYCLE | HUMDISEASE | SURVIVAL | BREAST-CANCER CELLS | ACTIVATION | RAS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | STAT3 | MECHANISMS | TUMORIGENESIS | EXPRESSION | IN-VITRO PROPAGATION | CELL BIOLOGY | NF-κB | IL6 | cellular transformation | let-7 | inflammation | cancer | positive feedback loop | epigenetics | Lin 28
Journal Article
NATURE, ISSN 0028-0836, 10/2018, Volume 562, Issue 7725, pp. 45 - 46
Epigenetic modifications affect chromatin structure and can have long-term effects on gene expression without changing the genome sequence. Seehawer and... 
MULTIPOTENCY | HEPATOCYTES | MULTIDISCIPLINARY SCIENCES | Medical research | Liver cancer | Cytokines | Epigenetics | Genomes | Mutation | Gene expression | Cancer | Tumors | Apoptosis
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7719, pp. 504 - 508
Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and the regulation of gene... 
SITE | METHYLATION | JMJC DOMAIN PROTEIN | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | HETEROCHROMATIN | HISTONE LYSINE METHYLTRANSFERASE | DYNAMICS | INHERITANCE | EXPRESSION | Methyltransferases - chemistry | Schizosaccharomyces pombe Proteins - chemistry | Histones - chemistry | Epigenesis, Genetic | Humans | Methyltransferases - metabolism | Cell Cycle Proteins - metabolism | Gene Silencing | Heterochromatin - chemistry | Cell Cycle Proteins - chemistry | Histone-Lysine N-Methyltransferase - chemistry | Schizosaccharomyces - genetics | Heterochromatin - genetics | Histone Methyltransferases - chemistry | Heterochromatin - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Schizosaccharomyces pombe Proteins - metabolism | Protein Conformation | Schizosaccharomyces - enzymology | Histone Methyltransferases - metabolism | Histones - metabolism | Methylation | Evolution, Molecular | Epigenetic inheritance | Methyltransferases | Analysis | Physiological aspects | Genetic research | Genetic regulation | Phosphorylation | Yeast | Peptides | Methyltransferase | Conservation | Amino acids | Homology | Genomes | Feedback loops | Catalytic activity | Positive feedback | Crystallography | Proteins | Demethylation | Heterochromatin | DNA methylation | Catalysis | Inhibition | Boundary element method | Deoxyribonucleic acid--DNA | Crystal structure | Enzymes | Stability | Gene expression | Substrates | Domains | Gene silencing | Hypotheses | Lysine | Proteomics | Epigenetics | Instability | Software | Scientific imaging | Mutation | Mass spectrometry | Histone H3 | Conformation
Journal Article
Genome Research, ISSN 1088-9051, 04/2011, Volume 21, Issue 4, pp. 555 - 565
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2016, Volume 64, Issue 6, pp. 1062 - 1073
Journal Article
Circulation, ISSN 0009-7322, 01/2019, Volume 139, Issue 1, pp. 119 - 133
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2016, Volume 138, Issue 42, pp. 14138 - 14151
MYC is overexpressed in many different cancer types and is an intensively studied oncogene because of its contributions to tumorigenesis. The regulation of MYC... 
TRANSCRIPTIONAL ACTIVATION | RIBONUCLEOPROTEIN-K | C-MYC | I-MOTIF | GENE-EXPRESSION | EPIGENETIC REGULATION | NUCLEASE HYPERSENSITIVE ELEMENT | HNRNP LL | SINGLE-STRANDED-DNA | BINDING PROTEIN | CHEMISTRY, MULTIDISCIPLINARY | Molecular dynamics | Cytosine | Research
Journal Article
The Journal of Pathology, ISSN 0022-3417, 12/2017, Volume 243, Issue 4, pp. 457 - 467
Journal Article
STEM CELLS, ISSN 1066-5099, 03/2014, Volume 32, Issue 3, pp. 802 - 815
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. 12365 - 12367
Journal Article