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epipolythiodioxopiperazines (70) 70
gliotoxin (36) 36
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chemistry, organic (20) 20
epipolythiodioxopiperazine (19) 19
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chaetomium cochliodes (5) 5
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RSC Advances, ISSN 2046-2069, 2019, Volume 9, Issue 28, pp. 16035 - 16039
The following compounds were isolated from acetate extracts of Chaetomium globosum 7951 solid cultures: demethylchaetocochin C (1) and chaetoperazine A (3),... 
EPIPOLYTHIODIOXOPIPERAZINES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Chemical Science, ISSN 2041-6520, 08/2015, Volume 6, Issue 8, pp. 4451 - 4457
Epipolythiodioxopiperazine (ETP) alkaloids are structurally elaborate alkaloids that show potent antitumor activity. However, their high toxicity and... 
APOPTOSIS | INHIBITION | EPIPOLYTHIODIKETOPIPERAZINE ALKALOIDS | METABOLITE CHAETOCIN | EPIPOLYTHIODIOXOPIPERAZINES | CHEMISTRY | BIOLOGICAL-ACTIVITIES | GENERAL-APPROACH | GLIOTOXIN | CANCER | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Organic Letters, ISSN 1523-7060, 04/2017, Volume 19, Issue 7, pp. 1698 - 1701
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2009, Volume 50, Issue 30, pp. 4310 - 4313
Organocatalytic α-sulfenylation of substituted piperazine-2,5-diones is reported through the use of cinchona alkaloids as Lewis bases and electrophilic sulfur... 
HYALODENDRIN | EPIPOLYTHIODIOXOPIPERAZINES | CHEMISTRY, ORGANIC | CHAETOCIN | ALDEHYDES | CHAETOMIUM COCHLIODES
Journal Article
MARINE DRUGS, ISSN 1660-3397, 12/2019, Volume 17, Issue 12, p. 664
The spread of studies on biodiversity in different environmental contexts is particularly fruitful for natural product discovery, with the finding of novel... 
diketopiperazines | METABOLITES | CHEMISTRY, MEDICINAL | FUNGUS | AROMATIC POLYKETIDES | HYALODENDRIN | biological activities | thiosilvatins | secondary metabolites | BIOSYNTHETIC GENE-CLUSTER | fungi | A-C | GLIOTOXIN | epipolythiodioxopiperazines | DERIVATIVES
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 01/2017, Volume 82, Issue 1, pp. 353 - 371
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2012, Volume 51, Issue 52, pp. 13062 - 13065
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2015, Volume 2015, Issue 31, pp. 6858 - 6871
A variety of new symmetrical and unsymmetrical diketopiperazines have been prepared from free amino acids by using a previously developed microwave‐assisted... 
Fused ring systems | Amino acids | Reactive oxygen species | Nitrogen heterocycles | Thiolation | EPICOCCINS | ANTIBIOTICS | ONE-POT SYNTHESIS | EPIPOLYTHIODIOXOPIPERAZINES | CHEMISTRY, ORGANIC | CHAETOCIN | PEPTIDES | AMINO-ACIDS | GLIOTOXIN
Journal Article
Synlett, ISSN 0936-5214, 12/2013, Volume 24, Issue 19, pp. 2563 - 2566
Abstract A novel base-catalysed approach to disubstituted epidithiodiketopiperazines (ETP) is described. The synthetic route involves a multicomponent reaction... 
letter | gliotoxin | multicomponent reactions | chaetocin | epidithiodiketopiperazine | chetomin | CELLS | ANTIBIOTICS GLIOTOXIN | EPIPOLYTHIODIOXOPIPERAZINES | CHEMISTRY, ORGANIC | HYPOXIA | ARANOTIN | SPORIDESMIN | INHIBITION | L-PROLINE ANHYDRIDE
Journal Article
Journal Article
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2012, Volume 53, Issue 4, pp. 380 - 382
Journal Article
Nanoscale, ISSN 2040-3364, 9/2014, Volume 6, Issue 2, pp. 1194 - 11952
Chetomin is a promising molecule with anti-tumor activities in the epipolythiodioxopiperazine family of fungal secondary metabolites; however, strong... 
METABOLITES | PHYSICS, APPLIED | FUNGUS | MATERIALS SCIENCE, MULTIDISCIPLINARY | KINZE EX FR | EPIPOLYTHIODIOXOPIPERAZINES | NANOMEDICINE | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | ANTI-ANGIOGENESIS | ANTIANGIOGENESIS | CHAETOMIUM COCHLIODES | ENDOTHELIAL GROWTH-FACTOR
Journal Article