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Oncotarget, 2017, Volume 8, Issue 3, pp. 5048 - 5056
Forkhead box D3 (FOXD3), as a transcriptional repressor, is well known to be involved in the regulation of development. Although FoxD3 is associated with... 
Ras/Raf/MEK/ERK signal pathway | FOXD3 | Colon cancer | EGFR | MIGRATION | METASTASIS | ANGIOGENESIS | colon cancer | GROWTH | MELANOMA-CELLS | EXPRESSION | PROGRESSION | CELL BIOLOGY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 2, pp. 845 - 851
Platelet-derived growth factor D (PDGF-D) signaling plays significant roles during the development and progression of human malignancies via interacting with... 
TSCC | PDGF-D/PDGFRβ | p38/AKT/ERK/EMT signal pathway | HEAD | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROENVIRONMENTAL REGULATION | EMT | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | OVEREXPRESSION | BIOPHYSICS | DISSEMINATION | PDGF-D/PDGFR beta | NECK | BIOLOGICAL INSIGHTS | RNA, Small Interfering - genetics | Phosphorylation | Cadherins - metabolism | Vimentin - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Epithelial-Mesenchymal Transition - genetics | Receptor, Platelet-Derived Growth Factor beta - genetics | Antigens, CD - genetics | Platelet-Derived Growth Factor - genetics | Proto-Oncogene Proteins c-akt - genetics | Antigens, CD - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Lymphokines - genetics | Snail Family Transcription Factors - genetics | Vimentin - genetics | Lymphokines - antagonists & inhibitors | Lymphokines - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Cadherins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Tongue Neoplasms - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Snail Family Transcription Factors - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Neoplasm Invasiveness | Tongue Neoplasms - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Tongue Neoplasms - pathology | Disease Progression | Platelet-Derived Growth Factor - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Line, Tumor | Platelet-Derived Growth Factor - antagonists & inhibitors | Cell Movement | RNA, Small Interfering - metabolism
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 05/2019, Volume 173, pp. 142 - 148
Microcystin-LR (MC-LR) is the most toxic and abundant microcystin that produced by cyanobacteria. Previous studies have shown MC-LR had acute toxic to thyroid,... 
Deiodinase | Chronic low dose | The p38/MAPK and MEK/ERK signal pathways | Toxic | Microcystin-LR | Thyroid | APOPTOSIS | RISKS | PROTEIN PHOSPHATASE 2A | MAPK | WATERBORNE EXPOSURE | BIOACCUMULATION | ENVIRONMENTAL SCIENCES | METABOLISM | TOXICOLOGY | ALTERS | Proteins | Chronic diseases | Physiological aspects | Thyroid hormones | Analysis | Index Medicus
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 2009, Volume 199, Issue 2, pp. 203 - 209
Our recent research demonstrates that the extracellular signal-regulated kinase (ERK) signal pathway is impaired in depressed animals, and such disruption is... 
Depression | CREB | Prefrontal cortex | Hippocampus | U0126 | ERK | TRANSCRIPTION FACTORS | ACTIVATED PROTEIN-KINASE | MAP KINASE | ANTIDEPRESSANT TREATMENT | ELEMENT-BINDING PROTEIN | ANXIETY-LIKE BEHAVIOR | FORCED SWIM STRESS | ELEVATED PLUS-MAZE | NEUROSCIENCES | MEMORY CONSOLIDATION | BEHAVIORAL SCIENCES | LONG-TERM POTENTIATION | Antidepressants | Depression, Mental
Journal Article
Journal Article
by Li, Y and Tian, L and He, XQ
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2017, Volume 10, Issue 6, pp. 6767 - 6773
Gastric carcinoma has unknown pathogenesis mechanism. Abnormal autophagy of cells is closely correlated with tumors such as gastric cancer. This study... 
TARGET | APOPTOSIS | BECLIN 1 | Rapamycin | INDUCTION | PATHOLOGY | GASTRIC-CANCER CELLS | MAPK | gastric carcinoma cells | cell autophagy | INHIBITION | ONCOLOGY | ROS | ERK signal pathway | CARCINOMA
Journal Article
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 03/2018, Volume 22, Issue 5, pp. 1241 - 1248
OBJECTIVE: Extracellular signal-regulated kinase (ERK)/mitogen activated protein kinase (MAPK) signal pathway participates in cell proliferation, cycle, and... 
MIGRATION | PROFILES | ERK/MAPK | Proliferation | AUTOPHAGY | TUMORS | MiR-16 | INVASION | Pituitary tumor | GASTRIC-CANCER | THYROID-CANCER | Cell cycle | PHARMACOLOGY & PHARMACY | MEK1 | EXPRESSION | EPIDEMIOLOGY | Apoptosis
Journal Article