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CANCERS, ISSN 2072-6694, 06/2019, Volume 11, Issue 7, p. 989
Tumor progression and pregnancy have several features in common. Tumor cells and placental trophoblasts share many signaling pathways involved in migration and... 
trophoblastic cell lines | APOPTOSIS | CDKN1A | ACTIVATION | PHOSPHORYLATION | MMP2 | PROLIFERATION | MECHANISMS | CYCLE REGULATORS | p21 | invasion | ONCOLOGY | ERK3 | TIMP2 | 1ST TRIMESTER | MAPK6 | HALLMARKS | EXPRESSION | ERK3/MAPK6
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2019, Volume 39, Issue 6
The physiological functions of the atypical mitogen-activated protein kinase extracellular signal-regulated kinase 3 (ERK3) remain poorly characterized.... 
Signal transduction | ERK3 | Mouse models | Protein kinases | MAP kinases | mouse models | ACTIVATION | signal transduction | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein kinases | LEADS | DEFINES | CELL BIOLOGY
Journal Article
Atlas of Genetics and Cytogenetics in Oncology and Haematology, ISSN 1768-3262, 2018, Volume 22, Issue 1, pp. 5 - 7
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2019, Volume 39, Issue 6
Mitogen-activated protein kinase 6/extracellular signal-regulated kinase 3 (MAPK6/ERK3) is an atypical member of the MAPKs. An essential role has been... 
MAPKAPK5/MK5 | Gene deletion | Protein kinase | Mitogen-activated protein kinases | INACTIVATION | GENE | ERK3 | mitogen-activated protein kinases | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFINES | protein kinase | MK5/PRAK | gene deletion | MAPKS | CELL BIOLOGY
Journal Article
Gene, ISSN 0378-1119, 04/2019, Volume 694, pp. 1 - 6
Pellino proteins are associated with immune and stress responses through their effects on NF-κB signaling and B-cell development, and through their role as a... 
ERK3/4 signaling | E3 ligase | peli1b | Brain patterning | zic3 | ACTIVATION | PHOSPHORYLATION | NOTCH | PELLINO PROTEINS | FAMILY | MEMBER | IRAK | ADAPTER | GENETICS & HEREDITY | INHIBITORS | EXPRESSION | Embryonic development | Ligases | Analysis
Journal Article
by Xin, L and Junhua, W and Long, L and Jun, Y and Yang, X
Current Molecular Medicine, ISSN 1566-5240, 09/2017, Volume 17, Issue 8, pp. 563 - 567
Background: Cerebral ischemia reperfusion (CIR) injury is the main pathological mechanism of ischemia stroke, and oxidative stress (OS) plays a vital role... 
Hydrogen sulfide | Reoxygenation | ERK3 | Nrf2 | Oxygen-glucose deprivation | P38MAPK | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | ACTIVATION | CEREBRAL ISCHEMIA/REPERFUSION | P38 MAPK | ISCHEMIA | reoxygenation | oxygen-glucose deprivation | KINASE PATHWAYS | NEURONS | DYSFUNCTION | INHIBITOR | p38MAPK | BRAIN
Journal Article
Scientific Reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, p. 46602
Neointima formation is the major reason for vein graft failure. However, the underlying mechanism is unclear. The aim of this study was to determine the role... 
PROGENITOR CELLS | HYPERTROPHY | APOPTOSIS | ANGIOGENESIS | ERK3 | MULTIDISCIPLINARY SCIENCES | GROWTH | DIFFERENTIATION | MIR-26A | EXPRESSION | REVEALS | Jugular vein | Cell proliferation | Autografts | Platelet-derived growth factor | Hyperplasia | MiRNA | Smooth muscle | mRNA | Platelet-derived growth factor BB | Rejection | Grafts | 3' Untranslated regions | Veins | Rodents | Carotid artery | Stents | Veins & arteries
Journal Article
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, ISSN 2296-634X, 2016, Volume 3, p. 88
Downstream of MAPKs, such as classical/atypical ERKs and p38 MAPKs, but not of JNKs, signaling is often mediated by protein kinases which are phosphorylated... 
dendritic cells | macrophage-specific activation | DMBA-induced skin tumors | common docking motif | DEVELOPMENTAL BIOLOGY | p38 MAPK | Ras-induced senescence | ERK3/4 | mouse gene-targeting strategy | CELL BIOLOGY | Tumor suppressor genes | Cellular signal transduction | Research | Protein kinases | Extracellular signal-regulated kinases | Dendritic Cells
Journal Article
Cell Reports, ISSN 2211-1247, 03/2016, Volume 14, Issue 11, pp. 2745 - 2760
Amino acid hydroxylation is a post-translational modification that regulates intra- and inter-molecular protein-protein interactions. The modifications are... 
HYPOXIA-INDUCIBLE FACTOR | FACTOR 1-ALPHA | PROTEIN INTERACTIONS | INHIBITING-HIF FIH | ALPHA | HIF-1-ALPHA | NF-KAPPA-B | PROLYL HYDROXYLASES | MASS-SPECTROMETRY | PROTEOMICS | CELL BIOLOGY | Immunoprecipitation | Humans | Substrate Specificity | Immunoblotting | Mixed Function Oxygenases - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Mixed Function Oxygenases - chemistry | Chromatography, High Pressure Liquid | Protein Interaction Maps | Ubiquitination | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | HEK293 Cells | Hypoxia-Inducible Factor 1, alpha Subunit - chemistry | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Amino Acids, Dicarboxylic - chemistry | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Amino Acid Sequence | Repressor Proteins - chemistry | Peptides - chemistry | Signal Transduction | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Mitogen-Activated Protein Kinase 6 - antagonists & inhibitors | Mitogen-Activated Protein Kinase 6 - metabolism | Repressor Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Protein-Serine-Threonine Kinases - chemistry | Mixed Function Oxygenases - genetics | Peptides - analysis | RNA, Small Interfering - metabolism
Journal Article
by Wu, JL and Zhao, YY and Li, FL and Qiao, BH
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, ISSN 1138-7548, 06/2019, Volume 75, Issue 2, pp. 143 - 152
Cervical cancer is the third most common gynecologic cancer in the world. Exploration of the molecular mechanism underlying cervical cancer pathogenesis will... 
PHYSIOLOGY | METASTASIS | PROMOTES CELL-PROLIFERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Hela | miR-144-3p | INVASION | HCC94 | ERK3 | GROWTH | MAPK6 | MICRORNA EXPRESSION | CARCINOMA | Cervical cancer | Analysis | Metastasis
Journal Article
Frontiers in Bioscience - Landmark, ISSN 1093-9946, 01/2016, Volume 21, Issue 2, pp. 374 - 384
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2012, Volume 32, Issue 13, pp. 2467 - 2478
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ORGANIZATION | ACTIVATION | KALIRIN-7 | ERK3 | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINE MORPHOGENESIS | MAMMALIAN SEPTINS | MAP KINASES | CELL-CYCLE | MK5/PRAK | CELL BIOLOGY | Protein-Serine-Threonine Kinases - deficiency | Humans | DNA Primers - genetics | Dendrites - ultrastructure | Intracellular Signaling Peptides and Proteins - metabolism | Recombinant Fusion Proteins - metabolism | MAP Kinase Signaling System | Intracellular Signaling Peptides and Proteins - deficiency | Multiprotein Complexes - metabolism | Neurons - ultrastructure | Transfection | Guanine Nucleotide Exchange Factors - metabolism | Base Sequence | HEK293 Cells | GTP-Binding Protein Regulators - metabolism | Neurons - metabolism | Septins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Dendrites - metabolism | Septins - genetics | Protein-Serine-Threonine Kinases - genetics | Mitogen-Activated Protein Kinase 6 - metabolism | Recombinant Fusion Proteins - chemistry | Hippocampus - cytology | Mitogen-Activated Protein Kinase 6 - chemistry | Mice, Knockout | Hippocampus - metabolism | Multiprotein Complexes - chemistry | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Neurogenesis - physiology | Recombinant Fusion Proteins - genetics | Mice | Protein-Serine-Threonine Kinases - chemistry | HeLa Cells | Models, Neurological | Mitogen-Activated Protein Kinase 6 - genetics | Septins - chemistry
Journal Article
Journal Article
Journal of hematology & oncology, ISSN 1756-8722, 02/2017, Volume 10, Issue 1, pp. 59 - 59
Journal Article
Journal Article