X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (415) 415
Publication (88) 88
Dissertation (6) 6
Book Chapter (4) 4
Conference Proceeding (2) 2
Book Review (1) 1
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
erk5 (316) 316
index medicus (217) 217
humans (191) 191
animals (175) 175
mitogen-activated protein kinase 7 - metabolism (165) 165
biochemistry & molecular biology (119) 119
cell biology (117) 117
mice (104) 104
phosphorylation (102) 102
expression (98) 98
mitogen-activated protein kinase 7 - genetics (96) 96
activation (84) 84
signal transduction (83) 83
pathway (76) 76
activated protein-kinase (73) 73
apoptosis (66) 66
gene-expression (66) 66
kinases (58) 58
oncology (58) 58
male (55) 55
map kinase (55) 55
cells, cultured (52) 52
rats (52) 52
bmk1/erk5 (51) 51
article (50) 50
cancer (50) 50
cell line, tumor (47) 47
proteins (47) 47
cell proliferation (43) 43
map kinase kinase 5 - metabolism (40) 40
proliferation (40) 40
growth-factor (39) 39
female (37) 37
survival (37) 37
protein (36) 36
signaling pathway (36) 36
cells (35) 35
gene expression (35) 35
mek5 (33) 33
mitogen-activated protein kinase 7 - antagonists & inhibitors (33) 33
signal-regulated kinase-5 (33) 33
targeted deletion (33) 33
analysis (32) 32
cell line (32) 32
nf-kappa-b (32) 32
enzyme activation (31) 31
protein kinases (31) 31
prostate-cancer (30) 30
research (30) 30
biophysics (29) 29
growth (29) 29
neurosciences (29) 29
erk1/2 (28) 28
signal transduction - drug effects (28) 28
genetic aspects (27) 27
cell-proliferation (26) 26
mitogen-activated protein kinases - metabolism (26) 26
identification (25) 25
kinase (25) 25
mapk (25) 25
physiological aspects (25) 25
protein kinase inhibitors - pharmacology (24) 24
signal transduction - physiology (24) 24
breast-cancer (23) 23
gene expression regulation, neoplastic (23) 23
inhibition (23) 23
map kinase kinase 5 - genetics (23) 23
signal-transduction (23) 23
differentiation (22) 22
blotting, western (21) 21
development and progression (21) 21
metastasis (21) 21
mitogen-activated protein kinase 1 - metabolism (21) 21
epidermal-growth-factor (20) 20
map kinase signaling system (20) 20
mitogen-activated protein kinase 7 (20) 20
mitogens (20) 20
protein-kinase (20) 20
transcriptional activation (20) 20
tyrosine kinases (20) 20
cardiac & cardiovascular systems (19) 19
cell survival (19) 19
endothelial-cells (19) 19
endothelium (19) 19
genetics & heredity (19) 19
health aspects (19) 19
mef2 transcription factors (19) 19
mitogen-activated protein kinase 3 - metabolism (19) 19
research article (19) 19
angiogenesis (18) 18
breast cancer (18) 18
erk5/bmk1 (18) 18
inflammation (18) 18
medicine, research & experimental (18) 18
mitogen-activated protein kinase 7 - physiology (18) 18
neurons (18) 18
phosphorylation - drug effects (18) 18
phosphotransferases (18) 18
transfection (18) 18
atherosclerosis (17) 17
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Stem Cell Reports, ISSN 2213-6711, 10/2018, Volume 11, Issue 4, pp. 929 - 943
Tyrosine kinase inhibitors (TKi) are effective against chronic myeloid leukemia (CML), but their inefficacy on leukemia stem cells (LSCs) may lead to relapse.... 
microenvironment | hypoxia | stem cell niche | CML | leukemia stem cells | MAPK7 | ERK5/MAPK | tyrosine kinase inhibitors/TKi | combination therapy | MAP2K5 | IN-VITRO | LOW-OXYGEN | REPOPULATING ABILITY | ERK5 | IMATINIB | BONE-MARROW-CELLS | PROLIFERATION | HYPOXIA | CANCER | MEK5/ERK5 PATHWAY | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
ACS Combinatorial Science, ISSN 2156-8952, 08/2016, Volume 18, Issue 8, pp. 444 - 455
Journal Article
EUROPEAN RESPIRATORY JOURNAL, ISSN 0903-1936, 02/2019, Volume 53, Issue 2
Journal Article
Cardiovascular Research, ISSN 0008-6363, 01/2015, Volume 105, Issue 1, pp. 86 - 95
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 10/2019, Volume 72, p. 108219
Epithelial–mesenchymal transition (EMT) contributes to the initiation, invasion, metastasis and drug resistance of cancer. The function of extracellular... 
Epithelial–mesenchymal transition | AP-1 | Lung cancer | Sulforaphane | ERK5
Journal Article
Biochimie, ISSN 0300-9084, 08/2019, Volume 163, pp. 152 - 162
Extra-cellular signal regulated kinase-5 (Erk-5), a transcriptional activator and regulator of endothelial cells (ECs) homeostasis, has been implicated in... 
pHUVECs | Endothelial dysfunction | Fisetin | Erk-5 signaling | Atherosclerosis | Oxidized-LDL | CELLS | METABOLIC SYNDROME | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RISK | FACTOR-2 KLF2 | BMK1/ERK5 | INFLAMMATION | ERK5 | EXPRESSION | Flavonoids | Flavones | RNA | Bioflavonoids | Low density lipoproteins | Stress (Physiology) | Blood lipids | Endothelium
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 11/2014, Volume 34, Issue 11, pp. 2378 - 2386
Atherosclerosis is a focal disease that develops preferentially where non-laminar, disturbed blood flow (d-flow) occurs such as branches, bifurcations, and... 
p90RSK | SUMOylation | PKCζ | flow | ERK5
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2018, Volume 28, Issue 13, pp. 2294 - 2301
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bmcl.2018.05.029 
MEDICINAL CHEMISTRY | CELLS | CROSS-COUPLING REACTIONS | CHEMISTRY, MEDICINAL | HALOGEN BONDS | ERK5 | CHEMISTRY, ORGANIC | COPPER | INHIBITORS | MICROWAVE-ASSISTED SYNTHESIS | MEK5/ERK5 PATHWAY | ALKYNE CYCLOADDITION | Drugstores | Surface active agents | Protein kinases | Mitogens | Pharmacy
Journal Article
Oncogene, ISSN 0950-9232, 05/2018, Volume 37, Issue 19, pp. 2601 - 2614
Journal Article
Journal Article
Journal Article
Biochimica et Biophysica Acta - Molecular Cell Research, ISSN 0167-4889, 09/2011, Volume 1813, Issue 9, pp. 1619 - 1633
Journal Article
International Journal of Oncology, ISSN 1019-6439, 04/2017, Volume 50, Issue 4, pp. 1321 - 1329
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2012, Volume 24, Issue 1, pp. 170 - 180
The pro-apoptotic BH3 only protein BIM is phosphorylated by ERK1/2 and this targets it for proteasome-dependent degradation. A recent study has shown that... 
Nocodazole | Mitosis | BIM | ERK5 | Paclitaxel | CDK1
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2013, Volume 70, pp. 758 - 767
The benzo[ ]pyrimido-[5,4- ]diazepine-6(11 )-one core was discovered as a novel ERK5 (also known as MAPK7 and BMK1) inhibitor scaffold, previously. Further... 
ERK5 inhibitor | Benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-one | Kinase selectivity | Benzo[e]pyrimido-[5,4-b]diazepine-6(11H)- one | CELLS | CHEMISTRY, MEDICINAL | ACTIVATED PROTEIN-KINASE | INHIBITOR SELECTIVITY | POLO-LIKE-KINASE-1 | LRRK2 | PARKINSON DISEASE | PROSTATE-CANCER | IN-VIVO | EXPRESSION | CARCINOMA | Protein Kinase Inhibitors - chemical synthesis | Pyrimidines - chemical synthesis | Humans | Cells, Cultured | Azepines - chemical synthesis | Models, Molecular | Structure-Activity Relationship | Mitogen-Activated Protein Kinase 7 - metabolism | Pyrimidines - pharmacology | Enzyme Activation - drug effects | Pyrimidines - chemistry | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Azepines - pharmacology | Dose-Response Relationship, Drug | Protein Kinase Inhibitors - chemistry | Azepines - chemistry | Mitogen-Activated Protein Kinase 7 - antagonists & inhibitors | HEK293 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Molecular Structure | Protein Kinase Inhibitors - pharmacology | HeLa Cells | Protein-Serine-Threonine Kinases - metabolism | Medical colleges | Phosphotransferases | Epidermal growth factor | PLK, polo-like kinase | EGF, epidermal growth factor | PML, promyelocytic leukemia protein | X-phos, 2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-biphenyl | DIEA, N,N-diisopropylethylamine | DMA, N,N-dimethylacetamide | ERK5, extracelluar-signal-regulated kinase 5 | LRRK2, leucine rich repeat kinase 2 | BMK1, big MAP kinase 1 | ERK5, mitogen-activated protein kinase 7 | RSK, ribosomal S6 kinase | SAR, structure–activity relationship | Pd2(dba)3, tris(dibenzylideneacetone)dipalladium- | HCC, hepatocellular carcinoma | Original | DCAMKL2, doublecortin and CaM kinase-like 2 | MAPK, mitogen-activated protein kinase | MEK5, MAP kinase kinase 5
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 42, pp. 11865 - 11870
Unlike other members of the MAPK family, ERK5 contains a large C-terminal domain with transcriptional activation capability in addition to an N-terminal... 
Inflammation | Bromodomain | Proliferation | Kinase | ERK5 | ACTIVATED PROTEIN-KINASE | SIGNAL-REGULATED KINASE-5 | proliferation | BRONCHIAL EPITHELIAL-CELLS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | bromodomain | kinase | IN-VITRO | INHIBITION | BMK1/ERK5 | inflammation | PATHWAY | GROWTH-FACTOR | BET BROMODOMAINS | Phosphorylation | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Transcriptome | Cell Survival - genetics | Gene Expression Profiling | Structure-Activity Relationship | Gene Knockdown Techniques | Inflammation - metabolism | Protein Kinase Inhibitors - chemistry | Immunity, Cellular - drug effects | Mitogen-Activated Protein Kinase 7 - antagonists & inhibitors | Inflammation Mediators - metabolism | Inhibitory Concentration 50 | Molecular Structure | Cytokines - genetics | Cell Survival - drug effects | Gene Expression | Human Umbilical Vein Endothelial Cells - drug effects | Cytokines - metabolism | Inflammation - immunology | Mitogen-Activated Protein Kinase 7 - genetics | Mitogen-Activated Protein Kinase 7 - metabolism | Gene Expression Regulation - drug effects | Animals | Biomarkers | Inflammation - genetics | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | HeLa Cells | Cell proliferation | Physiological aspects | Cell research | Immune response | Research | Extracellular signal-regulated kinases | Biological Sciences
Journal Article