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Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7631, pp. 80 - 85
In all domains of life, selenocysteine (Sec) is delivered to the ribosome by selenocysteine-specific tRNA (tRNA(Sec)) with the help of a specialized... 
EF-TU | ELECTRON CRYOMICROSCOPY | AMINOACYL-TRANSFER-RNA | SELENOCYSTEINE INSERTION-SEQUENCE | MESSENGER-RNA | FACTOR-TU | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SELENOPROTEIN SYNTHESIS | CRYO-EM | Selenocysteine - metabolism | Protein Biosynthesis | Ribosome Subunits, Large, Bacterial - metabolism | Codon, Terminator - genetics | Bacterial Proteins - chemistry | RNA, Transfer, Amino Acid-Specific - metabolism | Ribosomes - metabolism | GTP Phosphohydrolases - ultrastructure | Ribosomes - enzymology | Escherichia coli - metabolism | Protein Domains | Nucleic Acid Conformation | Binding Sites | Codon, Terminator - chemistry | Ribosome Subunits, Small, Bacterial - metabolism | Endoribonucleases - metabolism | Ribosome Subunits, Large, Bacterial - ultrastructure | Ribosomes - chemistry | Models, Molecular | RNA, Transfer, Amino Acid-Specific - genetics | Escherichia coli - chemistry | Codon, Terminator - metabolism | Cryoelectron Microscopy | RNA, Transfer, Amino Acid-Specific - chemistry | Ribosome Subunits, Small, Bacterial - ultrastructure | Ribosomes - ultrastructure | GTP Phosphohydrolases - metabolism | Ricin - metabolism | Escherichia coli - genetics | Ribosome Subunits, Large, Bacterial - chemistry | Protein Binding | Bacterial Proteins - metabolism | Bacterial Proteins - ultrastructure | Enzyme Activation | RNA, Transfer, Amino Acid-Specific - ultrastructure | Ribosome Subunits, Small, Bacterial - chemistry | Escherichia coli - ultrastructure | Fungal Proteins - metabolism | Physiological aspects | Protein research | Protein biosynthesis | Research | Guanosine triphosphatase | Ribosomes | Enzymes | E coli | Ribonucleic acid--RNA | Crystal structure | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 277 - 280
In order to survive, bacteria continually sense, and respond to, environmental fluctuations. Stringent control represents a key bacterial stress response to... 
EF-TU | ELECTRON CRYOMICROSCOPY | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | CRYO-EM | TRANSFER-RNA | RIBONUCLEIC ACID SYNTHESIS | PROTEIN-SYNTHESIS | RELA | GUANOSINE TETRAPHOSPHATE | Guanosine Tetraphosphate - chemistry | Phosphorylation | Protein Biosynthesis | RNA, Transfer, Amino Acyl - chemistry | Stress, Physiological | Ribosomes - metabolism | Escherichia coli Proteins - ultrastructure | RNA, Transfer - ultrastructure | Guanosine Tetraphosphate - metabolism | Escherichia coli - pathogenicity | Escherichia coli - metabolism | RNA, Transfer, Amino Acyl - metabolism | GTP Pyrophosphokinase - metabolism | RNA, Transfer - genetics | Escherichia coli Proteins - antagonists & inhibitors | GTP Pyrophosphokinase - ultrastructure | RNA, Transfer - chemistry | Binding Sites | Second Messenger Systems | Protein Structure, Tertiary | GTP Pyrophosphokinase - antagonists & inhibitors | RNA, Transfer - metabolism | Ribosomes - chemistry | Models, Molecular | Escherichia coli Proteins - metabolism | RNA, Transfer, Amino Acyl - genetics | Amino Acids - deficiency | Cryoelectron Microscopy | Ribosomes - ultrastructure | Metabolic Networks and Pathways | Escherichia coli - genetics | Adenosine - metabolism | GTP Pyrophosphokinase - genetics | Protein Conformation | Escherichia coli Proteins - chemistry | Gene Expression Regulation, Bacterial | Escherichia coli - ultrastructure | Microbiological research | Transcription factors | Escherichia coli | Ribosomes | Research | Virulence (Microbiology) | Transfer RNA | E coli | Antibiotics | Ribonucleic acid--RNA | Crystal structure | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2017, Volume 36, Issue 14, pp. 1996 - 1998
Bacteria owe much of their evolutionary success to the development of mechanisms that enable survival under harsh conditions; despite their importance,... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | RMF | TRANSLATION | MODULATION FACTOR | 100S RIBOSOME | CELL BIOLOGY | Humans | Ribosomes | Survivors | Proteins | Hibernation | Bacteria | Survival | Environmental conditions | Integrity | Index Medicus | Views | Microbiology, Virology & Host Pathogen Interaction | Protein Biosynthesis & Quality Control | Structural Biology
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2015, Volume 54, Issue 43, pp. 12791 - 12794
The creation of orthogonal large and small ribosomal subunits, which interact with each other but not with endogenous ribosomal subunits, would extend our... 
translation | synthetic biology | genetic code reprogramming | orthogonal ribosomes | ribosomal RNA engineering | ANGSTROM RESOLUTION | SITE | BACTERIAL RIBOSOME | RNA | ESCHERICHIA-COLI | EXPANSION | CHEMISTRY, MULTIDISCIPLINARY | Molecular biology | Index Medicus | Mutations | Covalence | Synthesis | Ribonucleic acids | Protein synthesis | Staples | Evolution | Translations
Journal Article
Science, ISSN 0036-8075, 8/2009, Volume 325, Issue 5943, pp. 1014 - 1017
Protein biosynthesis on the ribosome requires repeated cycles of ratcheting, which couples rotation of the two ribosomal subunits with respect to each other,... 
Proteins | Head | Messenger RNA | Ribosomes | Reports | Rotational states | Nucleotides | Rotation | Binding sites | Transfer RNA | Crystal structure | ANGSTROM RESOLUTION | COMPLEX | MESSENGER-RNA | TRANSFER-RNA TRANSLOCATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MOVEMENT | HYBRID STATE | TRANSLATION TERMINATION | BINDING | 70S RIBOSOME | Ribosomal Proteins - chemistry | Anticodon - metabolism | Protein Biosynthesis | RNA, Transfer, Phe - chemistry | Ribosome Subunits, Large, Bacterial - metabolism | Anticodon - chemistry | Ribosomes - metabolism | Crystallography, X-Ray | RNA, Messenger - metabolism | Ribosomal Proteins - metabolism | Escherichia coli Proteins - biosynthesis | Escherichia coli - metabolism | Nucleic Acid Conformation | RNA, Bacterial - metabolism | RNA, Transfer, Phe - metabolism | Ribosome Subunits, Small, Bacterial - metabolism | RNA, Transfer, Met - metabolism | Ribosome Subunits, Large, Bacterial - ultrastructure | Ribosomes - chemistry | Escherichia coli Proteins - metabolism | Escherichia coli - chemistry | Ribosome Subunits, Small, Bacterial - ultrastructure | Ribosomes - ultrastructure | RNA, Transfer, Met - chemistry | Ribosome Subunits, Large, Bacterial - chemistry | RNA, Bacterial - chemistry | Protein Conformation | RNA, Messenger - chemistry | Ribosome Subunits, Small, Bacterial - chemistry | Escherichia coli Proteins - chemistry | Escherichia coli - ultrastructure | Escherichia coli | Physiological aspects | Protein biosynthesis | Genetic aspects | Research | Structure | E coli | Molecular biology | Protein synthesis | Anticodons | Index Medicus
Journal Article