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NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 05/2019, Volume 47, Issue 8, pp. 4136 - 4152
The UvrA(2) dimer finds lesions in DNA and initiates nucleotide excision repair. Each UvrA monomer contains two essential ATPase sites: proximal (P) and distal... 
BINDING CASSETTE TRANSPORTER | BETA-HAIRPIN | RECOGNITION | (A)BC EXCINUCLEASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | ESCHERICHIA-COLI UVRA | ABC TRANSPORTERS | INCISION | PROTEINS
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2019, Volume 33, Issue 1, pp. 763 - 769
Nucleotide excision repair (NER) protects cells against diverse types of DNA damage, principally UV irradiation. In Escherichia coli, damage is recognized by 2... 
DNA tightropes | Fluorescence imaging | Cooperativity | DNA repair | PROTEIN | cooperativity | fluorescence imaging | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | DIMERIZATION | ESCHERICHIA-COLI-UVRA | NUCLEOTIDE EXCISION-REPAIR | NUCLEASE | CELL BIOLOGY | ROLES | BIOLOGY | BINDING | DOMAINS
Journal Article
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 02/2012, Volume 22, Issue 1, pp. 88 - 93
► The β-hairpin is introduced as a general tool for damage detection in NER. ► UvrA uses an active mechanism for damage scanning. ► The iron sulphur cluster of... 
XPD HELICASE | ATP HYDROLYSIS | COMPLEX | ACTIVATION | PROTEIN | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHARGE-TRANSPORT | ESCHERICHIA-COLI UVRA | GLYCOSYLASES | BINDING | CELL BIOLOGY | DNA - genetics | DNA - chemistry | Multigene Family | Animals | DNA Repair | Humans | Substrate Specificity | DNA - metabolism | DNA Damage | DNA repair | DNA
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2018, Volume 46, Issue 3, pp. 1256 - 1265
Journal Article
Book Chapter
STRUCTURE, ISSN 0969-2126, 04/2009, Volume 17, Issue 4, pp. 547 - 558
UvrA proteins are key actors in DNA damage repair and play an essential role in prokaryotic nucleotide excision repair (NER), a pathway that is unique in its... 
HELICASE-II | DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI UVRA | NUCLEOTIDE EXCISION-REPAIR | ATP-BINDING | CELL BIOLOGY | BIOPHYSICS | ABC-TRANSPORTER | PROTEIN-PROTEIN INTERACTIONS | GENE-PRODUCT | POLYMERASE-I
Journal Article
Journal Article