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Journal Article
Translational research : the journal of laboratory and clinical medicine, ISSN 1931-5244, 04/2015, Volume 165, Issue 4, pp. 512 - 530
Renal fibrosis is the hallmark of virtually all progressive kidney diseases and strongly correlates with the deterioration of kidney function. The... 
Internal Medicine | activating transcription factor 2 | inhibitor of kappa B | activator protein-1 | unilateral ureteral obstruction | AP-1 | CTGF | ANG II | TGF-β-inducible gene | TβRII | angiotensin-converting enzyme | bone morphogenetic protein receptor | Monocyte chemoattractant protein-1 | idiopathic pulmonary fibrosis | PPARγ | ARB | plasminogen activator inhibitor-1 | TAK1-binding protein 1 | receptor-regulated Smads | angiotensin II receptor blocker | MAPK kinase kinase kinase | stz | CCL2-CCR2 | uterine sensitization-associated gene-1 | ESRD | chronic kidney disease | TSP 1 | nuclear factor kappa B | acute tubular necrosis | mitogen-activated protein kinase | Peroxisome proliferator-activated receptor γ | TrKA | A Study of Cardiovascular Events in Diabetes | TAK1 | USAG-1 | ASCEND | transforming growth factor β1 | von Willebrand factor | βig-h3 | FSGS | MKKK | heparan sulfate proteoglycan | CCR1 | ACE | HSPG | BMP | MKK | bone morphogenetic protein | ECM | endothelin | thrombospondin type 1 | tyrosine receptor kinase A | ETA | focal segmental glomerular sclerosis | ATN | phosphodiesterase | TAB1 | ATF 2 | extracellular matrix | Kielin/chordin-like protein | JNK | RAAS | small interfering RNA | LRP | lipoprotein receptor-related protein | NF-κB | renin-angiotensin-aldosterone system | BMPR | PAI-1 | LC3 | TGF-β type I receptor | c-Jun N-terminal kinase | TβRI | IGF-1 | end-stage renal disease | MAPK | EMT | UUO | epithelial-to-mesenchymal transition | connective tissue growth factor | streptozotocin | Nox | ROS | mitogen-activated protein kinase kinase | insulin-like growth factor 1 | nicotinamide adenine dinucleotide phosphate oxidase | MCP-1 | tumor necrosis factor α | estimated glomerular filtration rate | vWF | CC motif chemokine ligand 2-CC receptor type 2 | TGF-β type II receptor | IκB | microtubule-associated protein 1 light chain 3 | PDE | TGF-β-activated kinase 1 | reactive oxygen species | CC receptor type 1 | Angiotensin II | CKD | endothelin A receptor | eGFR | VEGF | siRNA | TNF-α | R-Smads | vascular endothelial growth factor | KCP | TGF-β1 | IPF | Life Sciences & Biomedicine | Medical Laboratory Technology | Medicine, General & Internal | General & Internal Medicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Fibrosis - drug therapy | Signal Transduction | Humans | Transforming Growth Factor beta1 - metabolism | Drug Design | Transforming Growth Factor beta1 - genetics | Fibrosis - pathology | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - pathology | Oxidases | Phosphates | Niacinamide | Medical colleges | Development and progression | Transforming growth factors | Homeopathy | Materia medica and therapeutics | Purines | Chronic kidney failure | Nitric oxide | Therapeutics | Angiotensin | Bone morphogenetic proteins | Health aspects | Index Medicus | Abridged Index Medicus | bone morphogenic protein-7 | autophagy | transforming growth factor-β | NADPH oxidase | tumor necrosis factor-α | Kidney fibrosis | endothelin-1 | C-C motif chemokine | chemokine receptor
Journal Article
Life sciences (1973), ISSN 0024-3205, 08/2016, Volume 159, pp. 30 - 33
...-arrestin pathway selectivity at the endothelin receptors. Re-analysis of data may allow researchers to determine whether there is existing evidence that the endogenous... 
Pathway selectivity | ETB | Endothelin | ETA | Bosentan | G protein coupled receptors | Biased agonism | β-Arrestin | Biased antagonism | IRL1620 | Endothelin Receptor Antagonists - pharmacology | Animals | Receptors, Endothelin - agonists | Humans | Receptors, Endothelin - metabolism | Peptides - pharmacology | Physiological aspects | Analysis | Pulmonary hypertension | Ovarian cancer | G proteins | Index Medicus
Journal Article
International journal of peptide research and therapeutics, ISSN 1573-3149, 3/2019, Volume 25, Issue 1, pp. 107 - 114
Journal Article
Cellular signalling, ISSN 0898-6568, 08/2017, Volume 36, pp. 240 - 254
G-protein coupled receptor (GPCR) mediated activation of the MAPK signalling cascade is a key pathway in the induction of hypertrophic remodelling of the heart... 
Cardiac hypertrophy | Signalling | MAPK | GPCRs | Endothelin-1 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals, Newborn | Transcription, Genetic - drug effects | Rats, Wistar | Endothelin-1 - pharmacology | Humans | RNA, Messenger - genetics | Cardiomegaly - pathology | Male | RNA, Messenger - metabolism | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Animals | Myocytes, Cardiac - drug effects | Phenylephrine - pharmacology | Signal Transduction - drug effects | HEK293 Cells | Myocytes, Cardiac - metabolism | Receptor, Endothelin A - metabolism | Protein Kinase Inhibitors - pharmacology | Cardiomegaly - genetics | Heart | Endothelin | Genetic transcription | Physiological aspects | Protein kinases | Natriuretic peptides | Index Medicus | DPM, disintegrations per minute | CVD, cardiovascular disease | β-MHC, myosin heavy chain, β isoform | IEG, immediate early gene | ECC, excitation contraction coupling | NFAT, nuclear factor of activated T cells | ara-C, cytosine b-d-arabinofuranoside | BNP, brain natriuretic factor | ETB receptor, endothelin type B receptor | ECE, endothelin converting enzyme | ERK1 | 2, extracellular signal-regulated kinase 1 | Act D, actinomycin D | TCA, trichloroacetic acid | DN β-Arr1, dominant negative β-arrestin-1 | PD, PD184352 | GPCR, G-protein coupled receptor | α-MHC, myosin heavy chain, α isoform | MEF2, myocyte enhancer factor-2 | TAC, transverse aortic constriction | ET-1, endothelin-1 | Ang II, angiotensin II | PE, phenylepherine | ANF, atrial natriuretic factor | CN, calcineurin | DUSP6, dual specificity phosphatase-6 | ETA receptor, endothelin type A receptor | NRVMs, neonatal rat ventricular myocytes | MAPK, mitogen activated protein kinase | SRF, serum response factor
Journal Article
Journal Article