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Journal of Cellular Physiology, ISSN 0021-9541, 09/2017, Volume 232, Issue 9, pp. 2508 - 2518
Current manuscript is the first report indicating the ET‐1‐dependent upregulation of CaR receptor in cardiomyocytes and it shows that this upregulation allows... 
PHYSIOLOGY | STIMULATION | ENDOTHELIAL DYSFUNCTION | POLYAMINES | HEART-FAILURE | CARDIAC-HYPERTROPHY | NITRIC-OXIDE | MECHANISMS | HYPERTENSION | STRESS | EXPRESSION | CELL BIOLOGY | Adaptation, Physiological | Up-Regulation | Rats, Wistar | Endothelin-1 - pharmacology | Cardiomegaly - pathology | Receptors, Calcium-Sensing - metabolism | Receptor, Endothelin B - agonists | Transfection | RNA Interference | Heart Ventricles - pathology | Disease Models, Animal | Paracrine Communication | Receptor, Endothelin A - agonists | Isolated Heart Preparation | Ventricular Function, Left - drug effects | Cells, Cultured | Cardiomegaly - physiopathology | Receptor Activity-Modifying Protein 1 - metabolism | Receptor, Endothelin A - genetics | Myocytes, Cardiac - pathology | Receptor, Endothelin B - genetics | Animals | Myocytes, Cardiac - drug effects | Heart Ventricles - physiopathology | Signal Transduction - drug effects | Myocytes, Cardiac - metabolism | Receptors, Calcium-Sensing - drug effects | Receptor, Endothelin A - metabolism | Receptors, Calcium-Sensing - genetics | Heart Ventricles - metabolism | Nitric Oxide Synthase - metabolism | Receptor, Endothelin B - metabolism | Cardiomegaly - genetics | Nitric Oxide - metabolism | Ventricular Remodeling - drug effects | Cardiomegaly - metabolism | Heart Ventricles - drug effects | Heart | Endothelin | Heart cells | Hypertrophy | Endothelium | Calcium | Endothelin ETB receptors | Paracrine signalling | Tissues | Receptor activity modifying proteins | Receptors | Arginine | Rodents | Down-regulation | Inhibition | Heart diseases | Cars | Rats | Cardiomyocytes | siRNA | Endothelin 1 | Nitric-oxide synthase | NG-Nitroarginine methyl ester | Polymerase chain reaction | Endothelin receptors | Nitric oxide | Receptor mechanisms | Cell size | Ventricle | Calcium-sensing receptors
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2010, Volume 644, Issue 1-3, pp. 128 - 137
Organ culture is an method for investigating cellular mechanisms involved in upregulation of vasocontractile G-protein coupled receptors. We hypothesize that... 
MEK/ERK pathway | Cerebral arteries | G-protein coupled receptor upregulation | Vascular smooth muscle cells | U0126 | Organ culture | CELLS | ANGIOTENSIN-II RECEPTOR | 5-HT1B RECEPTOR | ENDOTHELIN-B RECEPTORS | MESENTERIC-ARTERIES | ORGAN-CULTURE | ISCHEMIA | KINASE INHIBITORS | SUBARACHNOID HEMORRHAGE | PHARMACOLOGY & PHARMACY | EXPRESSION | Receptor, Endothelin B - drug effects | Receptor, Serotonin, 5-HT1B - drug effects | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Middle Cerebral Artery - drug effects | Rats | Male | RNA, Messenger - metabolism | Rats, Sprague-Dawley | Up-Regulation - drug effects | Receptor, Endothelin B - genetics | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Receptors, Thromboxane - drug effects | Time Factors | Middle Cerebral Artery - metabolism | Polymerase Chain Reaction | Receptor, Serotonin, 5-HT1B - genetics | Receptors, Thromboxane - metabolism | Organ Culture Techniques | Immunohistochemistry | RNA | Comparative analysis | Arteries | Angiotensin | Angiotensin II receptors | Translation | G protein-coupled receptors | Transcription | Endothelin ETB receptors | Extracellular signal-regulated kinase | Smooth muscle | Muscle contraction | Serotonin S1 receptors | Polymerase chain reaction | Prostaglandins | Endothelin receptors | Serotonin receptors | Post-translation | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 12/2018, Volume 430, Issue 24, pp. 5105 - 5119
Extracellular domains of G-protein-coupled receptors act as initial molecular selectivity filters for subtype specific ligands and drugs. Chimeras of the human... 
cell-free expression | GPCR | nanodiscs | endothelin receptors | ligand selectivity | ETB-RECEPTOR | ANGIOTENSIN-II RECEPTOR | 2ND EXTRACELLULAR LOOP | DISULFIDE BRIDGES | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROPEPTIDE-Y | STRUCTURAL BASIS | MEMBRANE-PROTEINS | BINDING | EXPRESSION | Fluorescence | Albumin | Endothelin | Analysis | Freedom of speech
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167778
Journal Article
Journal Article