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1. Full Text L'etoposide change-t-il le profil evolutif des syndromes d'activation macrophagique ?
by Naceur, I and Daoud, F and Aydi, Z and Rachdi, I and Dhaou, B. Ben and Boussema, F
La Revue de medecine interne, ISSN 0248-8663, 06/2017, Volume 38, p. A205-A206
Le syndrome d'activation macrophagique (SAM) ou lympho-histiocytose hemophagocytaire est une entite clinico-biologique rare pouvant compliquer plusieurs... 
Etoposide
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2. Full Text L'etoposide change-t-il le profil evolutif des syndromes d'activation macrophagique ?
by Naceur, I and Daoud, F and Aydi, Z and Rachdi, I and Ben Dhaou, B and Boussema, F
La Revue de medecine interne, ISSN 0248-8663, 06/2017, Volume 38, p. A205
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.revmed.2017.03.303 Le... 
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3. Full Text Molecular mechanisms of etoposide
by Montecucco, Alessandra and Zanetta, Francesca and Biamonti, Giuseppe
EXCLI Journal, 01/2015, Volume 14, pp. 95 - 108
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4. Full Text Isothermal microcalorimetric investigation of the toxic action of the effective constituents of Podophyllum emodi Wall on Tetrahymena thermophila [BF.sub.5]
by Gong, M and Zhang, N and Sun, Y.-Q and Luo, S.-Q and Zhao, Y.-L and Wang, X.Z and Yan, D and Xiao, X.-H and Li, J
Journal of Thermal Analysis and Calorimetry, ISSN 1388-6150, 03/2014, Volume 115, Issue 3, p. 2369
The effects of podophyllotoxin (PPT), etoposide (VP16), and teniposide (VM26) on the growth of Tetrahy mena thermophila [BF.sub.5] (T.t.[BF.sub.5]) was... 
Etoposide
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5. Screening assessment - Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-[beta]-D-glucopyarnosyl]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)- (Etoposide)
: Chemical Abstracts Service registry number 33419-42-0
and Canada. Environment Canada, issuing bodyCanada. Health Canada, issuing body
2015, ISBN 9781100256603
Toxicology | Etoposide
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6. Full Text Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
by Chyuan-Chuan Wu and Tsai-Kun Li and Lynn Farh and Li-Ying Lin and Te-Sheng Lin and Yu-Jen Yu and Tien-Jui Yen and Chia-Wang Chiang and Nei-Li Chan
Science, ISSN 0036-8075, 7/2011, Volume 333, Issue 6041, pp. 459 - 462
Type II topoisomerases (TOP2s) resolve the topological problems of DNA by transiently cleaving both strands of a DNA duplex to form a cleavage complex through... 
Protein isoforms | Molecules | Molecular structure | DNA | Drug interactions | REPORTS | Antineoplastics | Biochemistry | Nucleotides | Genetic mutation | Monomers | TARGET | DNA TOPOISOMERASE | COMPLEX | ENZYME | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | ALPHA | CLEAVAGE | CANCER | BETA | Humans | Protein Multimerization | Crystallography, X-Ray | Drug Resistance, Neoplasm | Structure-Activity Relationship | DNA-Binding Proteins - metabolism | Topoisomerase II Inhibitors - chemistry | DNA Topoisomerases, Type II - chemistry | Protein Structure, Quaternary | Protein Structure, Tertiary | DNA Topoisomerases, Type II - metabolism | Catalytic Domain | Etoposide - analogs & derivatives | Etoposide - pharmacology | Models, Molecular | Etoposide - metabolism | Mutant Proteins - metabolism | Topoisomerase II Inhibitors - pharmacology | DNA - metabolism | Topoisomerase II Inhibitors - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | DNA - chemistry | Base Pairing | Mutant Proteins - chemistry | DNA Topoisomerases, Type II - genetics | Etoposide - chemistry | Mutation | Antimitotic agents | Topoisomerases | Etoposide | Physiological aspects | Research | Antineoplastic agents | Health aspects | Proteins | Enzymes | Pharmacology | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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7. Full Text Death receptor-4 expression is regulated by transcription factor NF-IoB in response to etoposide treatment
by Mendoza, Francisco Jose and Ishdorj, Ganchimeg and Hu, Xiaojie and Gibson, Spencer B
Apoptosis - An International Journal on Programmed Cell Death, ISSN 1360-8185, 06/2008, Volume 13, Issue 6, p. 756
Tumour necrosis factor related apoptosis inducing ligand (TRAIL) binds to death receptor 4 (DR4) activating the apoptotic signalling pathway. DNA damaging... 
Etoposide
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8. Full Text Erratum to "Erythropoietin protects neuroblastoma cells against etoposide and vincristine by activating ERK and AKT pathways but has no effect in kidney cells" [Life Sci. 137(2015) 142-149]
by Vazquez-Mellado, Maria Jose and Aguilar, Cecilia and Rocha-Zavaleta, Leticia
Life sciences, ISSN 0024-3205, 03/2017, Volume 172, pp. 1 - 1
Erythropoietin | Etoposide
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9. Full Text Long‐term follow‐up of dose‐adjusted EPOCH plus rituximab (DA‐EPOCH‐R) in untreated patients with poor prognosis large B‐cell lymphoma. A phase II study conducted by the Spanish PETHEMA Group
by Purroy, Noelia and Bergua, Juan and Gallur, Laura and Prieto, Julio and Lopez, Luis A and Sancho, Juan M and García‐Marco, Jose A and Castellví, Josep and Montes‐Moreno, Santiago and Batlle, Ana and Villambrosia, Sonia Gonzalez and Carnicero, Fernando and Ferrando‐Lamana, Lucía and Piris, Miguel A and Lopez, Andrés
British Journal of Haematology, ISSN 0007-1048, 04/2015, Volume 169, Issue 2, pp. 188 - 198
This prospective multi‐institutional phase II study was designed to assess the efficacy and safety of dose‐adjusted EPOCH (etoposide, prednisone, vincristine,... 
vincristine | and rituximab | large B‐cell lymphoma | cyclophosphamide | doxorubicin | dose‐adjusted‐EPOCH‐R (etoposide, prednisone | high‐risk patients | cell of origin | Dose-adjusted-EPOCH-R (etoposide, prednisone | Cyclophosphamide | And rituximab | Cell of origin | Large B-cell lymphoma | High-risk patients | Doxorubicin | Vincristine | SURVIVAL | DLBCL | BCL-2 GENE | REGIMEN | GERMINAL CENTER | CHEMOTHERAPY | high-risk patients | large B-cell lymphoma | PROTEIN EXPRESSION | dose-adjusted-EPOCH-R (etoposide | NON-HODGKINS-LYMPHOMA | CHOP | TISSUE MICROARRAY | prednisone | HEMATOLOGY | Doxorubicin - therapeutic use | Prognosis | Humans | Middle Aged | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Young Adult | Neoplasm Grading | Adult | Female | Etoposide - adverse effects | Lymphoma, Large B-Cell, Diffuse - drug therapy | Prednisone - adverse effects | Lymphoma, Large B-Cell, Diffuse - pathology | Rituximab | Etoposide - therapeutic use | Treatment Outcome | Lymphoma, Large B-Cell, Diffuse - mortality | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Vincristine - therapeutic use | Vincristine - adverse effects | Aged | Neoplasm Staging | Doxorubicin - adverse effects | Prednisone - therapeutic use | Medical research | Anthracyclines | Corticosteroids | Analysis | Clinical trials | Medicine, Experimental | Etoposide | Lymphomas | Prednisone | Index Medicus
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10. Phase II study of cisplatin, etoposide and paclitaxel in locally advanced or metastatic adenocarcinoma of gastric/ gastroesophageal junction
by Sharma, A and Raina, V and Lokeshwar, N and Deo, S. V. S and Shukla, N. K and Mohanti, B. K
Phase II study of cisplatin, etoposide and paclitaxel in locally advanced or metastatic adenocarcinoma of gastric/ gastroesophageal junction, 12/2006
Background: Unresectable and metastatic gastric cancers carry a poor and dismal prognosis. Several phase II studies have identified effective anticancer drugs.... 
Cisplatin, etoposide, gastric, gastroesophageal, paclitaxel
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11. Full Text Etoposide, cisplatin–etoposide, methotrexate, actinomycin-D as primary treatment for management of very-high-risk gestational trophoblastic neoplasia
by Cyriac, Sanju and Rajendranath, Rejiv and Sridevi, Veluswami and Sagar, Tenali G
International Journal of Gynecology & Obstetrics, ISSN 0020-7292, 2011, Volume 115, Issue 1, pp. 37 - 39
Abstract Objective To evaluate the efficacy of etoposide, cisplatin–etoposide, methotrexate, actinomycin-D (EP–EMA) chemotherapy as the frontline treatment for... 
Obstetrics and Gynecology | Chemotherapy | Salvage | Etoposide, cisplatin–etoposide, methotrexate, actinomycin-D | Trophoblastic disease | Etoposide, cisplatin–etoposide, methotrexate, actinomycin‐D | Etoposide, cisplatin-etoposide, methotrexate, actinomycin-D | CYCLOPHOSPHAMIDE | GTT | REGIMEN | CISPLATIN/ETOPOSIDE | VINCRISTINE CHEMOTHERAPY | TUMORS | OBSTETRICS & GYNECOLOGY | DISEASE | EMA/CO | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Etoposide - administration & dosage | Risk | Survival Rate | Treatment Outcome | Dactinomycin - administration & dosage | Gestational Trophoblastic Disease - therapy | Disease Progression | Cisplatin - administration & dosage | India | Pregnancy | Young Adult | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adult | Female | Methotrexate - administration & dosage | Gestational Trophoblastic Disease - pathology | Retrospective Studies | Liver Neoplasms - secondary | Gestational Trophoblastic Disease - drug therapy | Salvage Therapy - methods | Etoposide | Dactinomycin | Methotrexate | Cancer | Index Medicus
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12. Full Text New angiopep-modified doxorubicin (ANG1007) and etoposide (ANG1009) chemotherapeutics with increased brain penetration
by Ché, Christian and Yang, Gaoqiang and Thiot, Carine and Lacoste, Marie-Claude and Currie, Jean-Christophe and Demeule, Michel and Régina, Anthony and Béliveau, Richard and Castaigne, Jean-Paul
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2010, Volume 53, Issue 7, pp. 2814 - 2824
This report describes the synthesis and preliminary biological characterization of 2 (ANG1007) and 3 (ANG1009), two new chemical entities under development for... 
DELIVERY VECTOR ANGIOPEP-2 | BREAST-CANCER | LUNG-CANCER | CHEMISTRY, MEDICINAL | PROTEIN | TRANSPORTER | DISRUPTION | BARRIER | GLYCOPROTEIN-DEFICIENT MICE | MULTIDRUG-RESISTANCE GENE | P-GLYCOPROTEIN | Doxorubicin - therapeutic use | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Humans | Brain Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Doxorubicin - chemistry | Brain Neoplasms - metabolism | Antineoplastic Agents - metabolism | Brain - metabolism | Peptides - metabolism | Peptides - toxicity | Biological Transport | Doxorubicin - analogs & derivatives | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Doxorubicin - metabolism | Amino Acid Sequence | Brain - cytology | Etoposide - toxicity | Etoposide - analogs & derivatives | Peptides - chemistry | Etoposide - pharmacology | Etoposide - metabolism | Etoposide - therapeutic use | Antineoplastic Agents - chemistry | Brain Neoplasms - drug therapy | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Peptides - pharmacology | Animals | Brain - pathology | Cell Line, Tumor | Etoposide - chemistry | Mice | Kinetics | Cell Cycle - drug effects | Doxorubicin - pharmacology | Peptides - therapeutic use | Index Medicus
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13. Full Text Transdermal Delivery of Etoposide Phosphate I: In Vitro and In Vivo Evaluation
by Patel, Hiren and Joshi, Abhay and Joshi, Amit and Stagni, Grazia
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 07/2016, Volume 105, Issue 7, pp. 2114 - 2122
Cancer chemotherapy frequently requires long periods of multiple intravenous infusions that often results in patients opting out of treatment. The main purpose... 
microporation | microdialysis | etoposide phosphate | transdermal | rabbit | etoposide | anti-cancer | chemotherapy | iontophoresis | CLINICAL-PHARMACOLOGY | CHEMISTRY, MEDICINAL | RABBIT SKIN | SOLID TUMORS | HUMAN PLASMA | DRUG-DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | CELL LUNG-CANCER | PHARMACOKINETICS | PIG SKIN | PHARMACOLOGY & PHARMACY | IONTOPHORETIC ADMINISTRATIONS | PHASE-I | Rabbits | Etoposide - analogs & derivatives | Area Under Curve | Skin - metabolism | Etoposide - administration & dosage | Skin Absorption | Etoposide - blood | Administration, Cutaneous | Antineoplastic Agents - administration & dosage | Chromatography, High Pressure Liquid | Irritants | Drug Delivery Systems | Iontophoresis | Animals | Microdialysis | Swine | Antineoplastic Agents - blood | Organophosphorus Compounds - blood | Female | Antineoplastic Agents - pharmacokinetics | Organophosphorus Compounds - administration & dosage | Organophosphorus Compounds - pharmacokinetics | Etoposide - pharmacokinetics | Index Medicus
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14. Full Text ANKRD49 inhibits etoposide-induced intrinsic apoptosis of GC-1 cells by modulating NF-[kappa]B signaling
by Zhou, Xia and Wang, Wen-tao and Sun, Jia and Liu, Hong-yan and Bai, Xin-yan and Liu, Juan-juan and Yu, Bao-feng
Molecular and Cellular Biochemistry, ISSN 0300-8177, 07/2019, Volume 457, Issue 1-2, p. 21
Proteins | Analysis | Etoposide | Apoptosis
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15. Full Text Population Pharmacokinetic Modeling of Etoposide Free Concentrations in Solid Tumor
by Pigatto, Maiara Cássia and de Araujo, Bibiana Verlindo and Torres, Bruna Gaelzer Silva and Schmidt, Stephan and Magni, Paolo and Dalla Costa, Teresa
Pharmaceutical Research, ISSN 0724-8741, 07/2016, Volume 33, Issue 7, pp. 1657 - 1670
This study aimed to determine free etoposide (ETO) concentrations in two regions of Walker-256 (W256) solid tumor using microdialysis and to establish a... 
drug tumor penetration | etoposide | microdialysis | anticancer | population pharmacokinetics | INTERSTITIAL FLUID PRESSURE | RATS | PROTEIN-BINDING | CHEMISTRY, MULTIDISCIPLINARY | BREAST-CANCER | CANCER-PATIENTS | PLASMA | TOPOISOMERASE-II INHIBITOR | ORAL ETOPOSIDE | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | Tissue Distribution - physiology | Animals | Microdialysis - methods | Neoplasms - blood | Rats, Wistar | Etoposide - pharmacology | Rats | Male | Etoposide - blood | Etoposide - pharmacokinetics | Neoplasms - drug therapy | Etoposide | Drugstores | Models | Analysis | Pharmacy | Tumors | Pharmacology | Kinetics | Index Medicus
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16. Full Text In-vitro dissolution and microbial inhibition studies on anticancer drug etoposide with [beta]-cyclodextrin
by Arumugam, Shanmuga Priya and Balakrishnan, Suganya Bharathi and Ganesan, Vigneshkumar and Munisamy, Maniyazagan and Kuppu, Sakthi Velu and Narayanan, Vimalasruthi and Baskaralingam, Vaseeharan and Jeyachandran, Sivakamavalli and Thambusamy, Stalin
Materials Science & Engineering C, ISSN 0928-4931, 09/2019, Volume 102, p. 96
In this article, we have reported the inclusion complex behaviors and their pharmaceutical application of anticancer drug property of Etoposide with... 
Analysis | Etoposide | Cyclodextrins
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17. Full Text Randomized Phase II Study of Bevacizumab in Combination With Chemotherapy in Previously Untreated Extensive-Stage Small-Cell Lung Cancer: Results From the SALUTE Trial
by David R. Spigel and Peter M. Townley and David M. Waterhouse and Liang Fang and Ibrahim Adiguzel and Jane E. Huang and David A. Karlin and Leonardo Faoro and Frank A. Scappaticci and Mark A. Socinski
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 16, pp. 2215 - 2222
Purpose Because of promising efficacy signals in single-arm studies, a placebo-controlled, double-blind, randomized phase II trial was designed to assess the... 
IRRADIATION | CARBOPLATIN | ETOPOSIDE | PLACEBO | CISPLATIN | ONCOLOGY | VEGF | DOUBLE-BLIND | IRINOTECAN | CARCINOMA | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Small Cell Lung Carcinoma - drug therapy | Bevacizumab | Cisplatin - administration & dosage | Carboplatin - adverse effects | Antibodies, Monoclonal, Humanized | Carboplatin - therapeutic use | Aged, 80 and over | Female | Etoposide - adverse effects | Double-Blind Method | Kaplan-Meier Estimate | Carboplatin - administration & dosage | Etoposide - administration & dosage | Etoposide - therapeutic use | Disease-Free Survival | Cisplatin - therapeutic use | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Small Cell Lung Carcinoma - mortality | Aged | Index Medicus
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18. Full Text P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 Determine the Pharmacokinetics of Etoposide
by Jurjen S. Lagas and Lin Fan and Els Wagenaar and Maria L.H. Vlaming and Olaf van Tellingen and Jos H. Beijnen and Alfred H. Schinkel
Clinical Cancer Research, ISSN 1078-0432, 01/2010, Volume 16, Issue 1, pp. 130 - 140
Purpose: Despite the extensive use of etoposide for the treatment of different malignant neoplasms, its main pharmacokinetic determinants are not completely... 
P-glycoprotein | Abcc3 | Etoposide | Abcc2 | Pharmacokinetics | HEPATOCELLULAR-CARCINOMA | TRANSPORT | ONCOLOGY | TIME PCR DATA | IN-VIVO | ORAL ETOPOSIDE | HUMAN LIVER | DRUG-RESISTANCE | UDP-GLUCURONOSYLTRANSFERASE 1A1 | KNOCKOUT MICE | MULTIDRUG-RESISTANCE PROTEIN-2 | Etoposide - urine | Animals | Feces - chemistry | Liver - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Male | Etoposide - blood | Mice | Multidrug Resistance-Associated Proteins - metabolism | Etoposide - pharmacokinetics | Mice, Knockout | Index Medicus
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19. Full Text Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ
by Oviatt, Alexandria A and Kuriappan, Jissy A and Minniti, Elirosa and Vann, Kendra R and Onuorah, Princess and Minarini, Anna and De Vivo, Marco and Osheroff, Neil
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2018, Volume 28, Issue 17, pp. 2961 - 2968
Etoposide is an anticancer drug that acts by inducing topoisomerase II-mediated DNA cleavage. Despite its wide use, etoposide is associated with some very... 
Etoposide | Topoisomerase IIα | Anticancer drug | DNA cleavage | Etoposide-polyamine hybrid | Topoisomerase IIβ | CELLS | CHEMISTRY, MEDICINAL | MOIETY | TRANSLOCATIONS | CHEMISTRY, ORGANIC | STRAND BREAKS | F14512 | INHIBITION | VECTORIZED ANTICANCER DRUG | Topoisomerase II alpha | Topoisomerase II beta | AGENTS | THERAPY-RELATED LEUKEMIA | DNA Topoisomerases, Type II - metabolism | Poly-ADP-Ribose Binding Proteins - metabolism | Polyamines - chemistry | Humans | Poly-ADP-Ribose Binding Proteins - antagonists & inhibitors | Etoposide - pharmacology | Structure-Activity Relationship | Topoisomerase II Inhibitors - pharmacology | Dose-Response Relationship, Drug | Polyamines - pharmacology | Topoisomerase II Inhibitors - chemistry | Isoenzymes - metabolism | Etoposide - chemistry | Ligands | Molecular Docking Simulation | Molecular Structure | Topoisomerase II Inhibitors - chemical synthesis | Etoposide - chemical synthesis | Isoenzymes - antagonists & inhibitors | Index Medicus
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20. Full Text Sequential vs Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer: Randomized Phase III Trial RTOG 9410
by Curran, Walter J and Paulus, Rebecca and Langer, Corey J and Komaki, Ritsuko and Lee, Jin S and Hauser, Stephen and Movsas, Benjamin and Wasserman, Todd and Rosenthal, Seth A and Gore, Elizabeth and Machtay, Mitchell and Sause, William and Cox, James D
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2011, Volume 103, Issue 19, pp. 1452 - 1460
Background The combination of chemotherapy with thoracic radiotherapy (TRT) compared with TRT alone has been shown to confer a survival advantage for good... 
IRRADIATION | CARBOPLATIN | CISPLATIN | VINORELBINE | ONCOLOGY | THERAPY-ONCOLOGY-GROUP | CHEMORADIOTHERAPY | RADIOTHERAPY | CHEMOTHERAPY | RADIATION-THERAPY | PACLITAXEL | Carcinoma, Non-Small-Cell Lung - radiotherapy | Lung Neoplasms - drug therapy | Multivariate Analysis | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Follow-Up Studies | United States | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Male | Vinblastine - administration & dosage | Cisplatin - administration & dosage | Time Factors | Vinblastine - adverse effects | Aged, 80 and over | Adult | Dose Fractionation | Chemotherapy, Adjuvant | Odds Ratio | Radiotherapy, Adjuvant | Carcinoma, Non-Small-Cell Lung - pathology | Radiotherapy Dosage | Etoposide - adverse effects | Drug Administration Schedule | Kaplan-Meier Estimate | Etoposide - administration & dosage | Treatment Outcome | Disease Progression | Canada | Confounding Factors (Epidemiology) | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Etoposide | Research | Lung cancer, Non-small cell | Drug therapy | Radiotherapy | Health aspects | Survival analysis | Oncology | Chemotherapy | Lung cancer | Clinical outcomes | Index Medicus
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