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Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 11/2001, Volume 2, Issue 11, pp. 827 - 837
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2021 - 2031
Epithelial cells that line the conducting airways provide the initial barrier and innate immune responses to the abundant particles, microbes, and allergens... 
MEDICINE, RESEARCH & EXPERIMENTAL | EARLY-LIFE | GM-CSF | INNATE | ALVEOLAR MACROPHAGES | ASTHMA | FETAL MONOCYTES | LUNG STEM | EXPOSURE | THYMIC STROMAL LYMPHOPOIETIN | ATOPIC SENSITIZATION | Chemotaxis, Leukocyte | Epithelial Cells - metabolism | Age Factors | Proto-Oncogene Proteins c-ets - genetics | Dendritic Cells - immunology | Th2 Cells - immunology | Recombinant Fusion Proteins - metabolism | Chemokine CCL20 - biosynthesis | Interleukins - genetics | Methacholine Chloride - pharmacology | Goblet Cells - physiology | Chemokine CCL20 - genetics | Cell Differentiation | Interleukins - biosynthesis | Transgenes | Cytokines - genetics | Pulmonary Eosinophilia - immunology | Animals, Newborn | Proto-Oncogene Proteins c-ets - physiology | Pulmonary Eosinophilia - metabolism | Antigens, Dermatophagoides - toxicity | Mice, Transgenic | Pulmonary Eosinophilia - pathology | Hepatocyte Nuclear Factor 3-gamma - physiology | Eosinophils - physiology | Metaplasia | Animals | Mice | Mice, Inbred BALB C | Pulmonary Eosinophilia - etiology | Cytokines - antagonists & inhibitors | Cytokines - biosynthesis | Lung - immunology | Physiological aspects | Transcription factors | Inflammation | Research | Cell differentiation | Epithelial cells | Hospitals | Cytokines | Rodents | Cloning | Mortality | Chronic obstructive pulmonary disease | Small intestine | Chemokines | Immune system | Acquisitions & mergers | Development | Genetics | Immunology | Therapeutics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2008, Volume 283, Issue 37, pp. 25404 - 25413
Angiogenesis is induced by multiple growth factors including vascular endothelial growth factor (VEGF) and fibroblast growth factor 2 (FGF2). In vascular... 
ETS TRANSCRIPTION FACTORS | VASCULAR DEVELOPMENT | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | HUMAN GLIOMAS | TUMOR ANGIOGENESIS | FLT-1 | FACTOR RECEPTOR | HYPOXIA-INDUCIBLE FACTOR-2-ALPHA | ENDOTHELIAL GROWTH-FACTOR | Transcription, Chromatin, and Epigenetics
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 2010, Volume 316, Issue 3, pp. 452 - 465
Background and Aims: SPDEF (also termed PDEF or PSE) is an ETS family transcription factor that regulates gene expression in the prostate and goblet cell... 
Paneth cell | Goblet cell | Intestine | Stem cell | Enteroendocrine cell | Proliferation | Transcription factor | PROGENITOR CELLS | PROSTATE-SPECIFIC ETS | GASTROINTESTINAL-TRACT | CELL BIOLOGY | BREAST-CANCER | MOUSE INTESTINE | ONCOLOGY | GENE-EXPRESSION | PDEF EXPRESSION | MOLECULAR-CLONING | PANETH CELLS | Organ Specificity - drug effects | Colonic Neoplasms - genetics | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Proto-Oncogene Proteins c-ets - genetics | Cell Count | Epithelial Cells - drug effects | Humans | Goblet Cells - drug effects | Protein Transport - drug effects | Stem Cells - cytology | Stem Cells - metabolism | Intestinal Mucosa - drug effects | DNA-Binding Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Proto-Oncogene Proteins c-ets - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Epithelial Cells - cytology | Intestinal Mucosa - ultrastructure | Transgenes - genetics | Goblet Cells - metabolism | Transcription Factors - metabolism | Animals | Cell Differentiation - drug effects | Colonic Neoplasms - pathology | Cell Line, Tumor | Stem Cells - drug effects | Doxycycline - pharmacology | Cell Proliferation - drug effects | Mice | Goblet Cells - cytology | Intestinal Mucosa - pathology | Phosphates | Anopheles | Colon cancer | Child development | Developmental biology | Analysis | Mucins | Stem cells | Universities and colleges | Gene expression | Models | Cellular biology | Colorectal cancer | PROSTATE | TRANSCRIPTION FACTORS | APOPTOSIS | LARGE INTESTINE | HOMEOSTASIS | NEOPLASMS | LUNGS | CELL PROLIFERATION | 60 APPLIED LIFE SCIENCES | IN VITRO | GENES | PHOSPHATES | STEM CELLS | CRYPT CELLS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16630 - 16635
Airway mucus plays a critical role in clearing inhaled toxins, particles, and pathogens. Diverse toxic, inflammatory, and infectious insults induce airway... 
Metaplasia | Intestines | Lungs | Epithelial cells | Lung diseases | Cell lines | Goblets | Infections | Mucus | Inflammation | Innate immunity | Airway epithelium | PULMONARY | innate immunity | RECOGNITION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | airway epithelium | HOST-DEFENSE | EXPRESSION | Epithelial Cells - metabolism | Lung Diseases - metabolism | Respiratory Mucosa - drug effects | Gene Expression - drug effects | Proto-Oncogene Proteins c-ets - genetics | Epithelial Cells - drug effects | Humans | Adaptor Proteins, Vesicular Transport - genetics | Rhinovirus - physiology | Lung Diseases - drug therapy | Adaptor Proteins, Vesicular Transport - metabolism | Respiratory Mucosa - pathology | HEK293 Cells | Proto-Oncogene Proteins c-ets - metabolism | Toll-Like Receptors - metabolism | Signal Transduction | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Interleukin-13 - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Host-Pathogen Interactions | Microscopy, Confocal | Animals | Epithelial Cells - virology | Toll-Like Receptors - genetics | Lipopolysaccharides - pharmacology | Protein Binding | Doxycycline - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Lung Diseases - pathology | Respiratory Mucosa - metabolism | Myeloid Differentiation Factor 88 - metabolism | Physiological aspects | Development and progression | Health aspects | Airway (Medicine) | Cytoplasm | Homeostasis | Body fluids | Toxins | T cell receptors | Interferon | Biological Sciences
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