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Autophagy, ISSN 1554-8627, 05/2015, Volume 11, Issue 5, pp. 796 - 811
The EWSR1 (EWS RNA-binding protein 1/Ewing Sarcoma Break Point Region 1) gene encodes a RNA/DNA binding protein that is ubiquitously expressed and involved in... 
Ewsr1 homozygous knockout | RISC, catalytic component 2 | DGCR8, DiGeorge syndrome critical region gene 8 | EWSR1, EWS RNA-binding protein 1/Ewing Sarcoma Break Point Region 1; Ewsr1 | RNA-seq, whole transcriptome sequencing | AGO2, argonaute | microtubule-associated protein 1 light chain 3 | ATG14, autophagy-related 14 | | BECN1, Beclin 1 | LAMP, lysosomal-associated membrane protein; MAP1LC3/LC3 | Mir351-specific antagomir | ATG5, autophagy-related 5 | Ant-Mir125a | Pep.A, pepstatin A | pri-miRNA, primary transcript miRNA | UVRAG | autophagy | Mir125a | + | Mir125a-specific antagomir | EWS, Ewing's Sarcoma | miRNA, microRNA | CQ, chloroquine | siRNA, small interfering RNA | Ant-Mir351 | ATG12, autophagy-related 12 | SQSTM1, sequestosome 1 | EWSR1 | MEF, mouse embryonic fibroblast | Mir351 | CNT-Ant, control antagomir | Ewsr1 wild type; ewsr1 | UVRAG, UV radiation-resistance associated | Autophagy | EWINGS-SARCOMA | PHOSPHATIDYLINOSITOL 3-KINASE | MULTIFUNCTIONAL PROTEIN | MICRORNAS | SYNTAXIN 17 | SARCOMA GENE EWS | CELL-DEATH | CELL BIOLOGY | MOLECULAR-MECHANISMS | SELF-DIGESTION | HOPS COMPLEX | NIH 3T3 Cells | Tumor Suppressor Proteins - metabolism | Molecular Sequence Data | MicroRNAs - metabolism | Calmodulin-Binding Proteins - metabolism | RNA-Binding Proteins | Down-Regulation - genetics | Mice, Knockout | Animals | Embryo, Mammalian - cytology | Base Sequence | Transcription, Genetic | Mice | Autophagy - genetics | Calmodulin-Binding Proteins - deficiency | Fibroblasts - metabolism | RNA-Binding Protein EWS
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 02/2019, Volume 43, Issue 2, pp. 220 - 228
Journal Article
Annales de Dermatologie et de Venereologie, ISSN 0151-9638, 12/2018, Volume 145, Issue 12, pp. 756 - 760
Background: Angiomatoid fibrous histiocytoma (AFH) is a slowly progressing rare soft-tissue tumour of moderate malignant potential. It is most commonly seen in... 
ATF1 | EWSR1 | Angiomatoid fibrous histiocytoma
Journal Article
Human Pathology, ISSN 0046-8177, 11/2019, Volume 93, pp. 65 - 73
is a ‘promiscuous’ gene that can fuse with many different partner genes in phenotypically identical tumors or partner with the same genes in morphologically... 
FISH | Molecular pathology | Next-generation sequencing | EWSR1
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2019, Volume 1865, Issue 7, pp. 1938 - 1945
Ewing's sarcoma (EWS) is a bone cancer arising predominantly in young children. ( / ) gene is ubiquitously expressed in most cell types, indicating it has... 
miRNA | Brain disorders | EWSR1 | Genetic mutation | Autophagy | Epigenetic function
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 02/2019, Volume 43, Issue 2, pp. 187 - 194
Adamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1-FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial... 
salivary gland | Ewing sarcoma | EWSR1 | FLI1 | adamantinoma-like Ewing sarcoma | TARGET | SURGERY | DIAGNOSIS | FUSION | PAROTID-GLAND | ADENOCARCINOMA | PATHOLOGY | THYROID-CARCINOMA | NKX2.2 | EWSR1 REARRANGEMENT | DIFFERENTIATION | FAMILY TUMOR ELEMENTS | Development and progression | Genetic aspects | Diagnosis | Salivary gland tumors | Ewing's sarcoma
Journal Article
Human Pathology, ISSN 0046-8177, 11/2018, Volume 81, pp. 281 - 290
Mesenchymal round cell tumors are a diverse group of neoplasms defined by primitive, often high-grade cytomorphology. The most common molecular alterations... 
NFATC2 | Ewing sarcoma | Myoepithelial | Soft tissue | Bone | EWSR1 | TRANSLOCATION | READ ALIGNMENT | PATHOLOGY | VARIANT | CHROMOSOME | MYOEPITHELIAL TUMORS | GENERATION | EWSR1 REARRANGEMENT | PAIRED-END | Antigens | Keratin | Sarcoma | Genes | Stem cells | Cancer | Polymerase chain reaction | Chemotherapy | Laboratories | Morphology | Tumors
Journal Article
American journal of clinical pathology, ISSN 0002-9173, 6/2013, Volume 139, Issue 6, pp. 771 - 779
Ewing family tumors (EFTs) and prostate carcinomas (PCa) are characterized by rearrangement of ETS genes, most commonly FLI1 (EFTs) and ERG (PCa). Previously,... 
EWSR1:ERG | Ewing’s tumor | EWSR1:FLI1 | EPR3864
Journal Article
BMB Reports, ISSN 1976-6696, 2015, Volume 48, Issue 7, p. 371
MicroRNAs (miRNAs) can regulate the expression of genes that are involved in multiple cellular pathways. However, their targets and mechanism of action... 
UVRAG | miR351 | EWSR1 | Autophagy | miR125a
Journal Article
Annals of Diagnostic Pathology, ISSN 1092-9134, 06/2017, Volume 28, pp. 19 - 23
To investigate that whether myoepithelial tumors of salivary glands (MTs) with EWSR1 rearrangement display distinctive morphological characteristics and... 
Translocation | Salivary glands | EWSR1 | Myoepithelial tumors | FISH
Journal Article
Journal of Cutaneous Pathology, ISSN 0303-6987, 12/2019, Volume 46, Issue 12, pp. 949 - 953
Isolated cases of basal cell carcinoma (BCC) with partial myoepithelial component have been described. However, myoepithelial differentiation has not been... 
myoepithelial carcinoma | sarcomatoid basal cell carcinoma | EWSR1‐PBX1 gene fusion | EWSR1 rearrangement | Chondrosarcoma | Carcinoma | Invasiveness | Glial fibrillary acidic protein | Case reports | Smooth muscle | Cell differentiation | FLI-1 protein | Gene fusion | PBX1 gene | Calponin | Osteosarcoma | Actin | Immunoreactivity
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 59, pp. 31397 - 31410
Epigenetic regulation is crucial in mammalian development and maintenance of tissue-cell specific functions. Perturbation of epigenetic balance may lead to... 
Epigenetic drug | Synergism effect | Ewing sarcoma | EWSR1 | PDX
Journal Article
Journal of Cutaneous Pathology, ISSN 0303-6987, 06/2019, Volume 46, Issue 6, pp. 421 - 424
Cutaneous syncytial myoepithelioma (CSM) is a recently recognized, histopathological variant of myoepithelial (ME) tumors of the skin. It is characterized by a... 
PBX3 | skin | EWSR1 | syncytial | myoepithelioma | NEOPLASM | PATHOLOGY | EXPRESSION | DERMATOLOGY | Immunohistochemistry | RNA sequencing | Genetic research | Keratin | Genes | Cytokeratin | Actin | Gene rearrangement | Stroma | Skin | Bone tumors | EWSR1 gene | Hybridization | Ribonucleic acid--RNA | Gene fusion | FLI-1 protein
Journal Article