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Molecular Cell, ISSN 1097-2765, 07/2004, Volume 15, Issue 1, pp. 95 - 105
The expression of polyglutamine-expanded mutant proteins in Huntington's disease and other neurodegenerative disorders is associated with the formation of... 
NEURONAL INTRANUCLEAR INCLUSIONS | YEAST | EXPANDED POLYGLUTAMINE | SCA1 MICE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | BODY FORMATION | HUNTINGTIN | EXPRESSION | BINDING | AGGREGATION | CELL BIOLOGY | Molecular Chaperones - metabolism | Exons | Neurodegenerative Diseases - etiology | Peptides - genetics | TATA-Box Binding Protein - metabolism | Nerve Tissue Proteins - toxicity | Cell Nucleus - metabolism | Peptides - metabolism | TATA-Box Binding Protein - genetics | Trans-Activators - genetics | Nuclear Proteins - genetics | CREB-Binding Protein | Molecular Chaperones - genetics | HSP70 Heat-Shock Proteins - genetics | Neurodegenerative Diseases - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Neurodegenerative Diseases - metabolism | Transcription Factors - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Nuclear Proteins - toxicity | Protein Folding | HSP70 Heat-Shock Proteins - metabolism | Macromolecular Substances | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Trinucleotide Repeat Expansion - genetics | Protein Conformation | Trans-Activators - metabolism | Mice | TATA-Box Binding Protein - antagonists & inhibitors | Trans-Activators - antagonists & inhibitors | Saccharomyces cerevisiae | Oligomers | Nervous system diseases | DNA binding proteins
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 02/2013, Volume 9, Issue 2, pp. 112 - 118
Journal Article
Progress in Neurobiology, ISSN 0301-0082, 2011, Volume 95, Issue 1, pp. 26 - 48
Journal Article
Nature, ISSN 0028-0836, 10/2001, Volume 413, Issue 6857, pp. 739 - 743
Proteins with expanded polyglutamine repeats cause Huntington's disease and other neurodegenerative diseases. Transcriptional dysregulation and loss of... 
LOCALIZATION | APOPTOSIS | EXPANDED POLYGLUTAMINE | CREB-BINDING PROTEIN | MULTIDISCIPLINARY SCIENCES | GROWTH | HUNTINGTONS-DISEASE | MAMMALIAN-CELLS | EXPRESSION | AGGREGATION | TRANSGENIC MICE | Acetyltransferases - metabolism | Histone Acetyltransferases | Glutamine - metabolism | E1A-Associated p300 Protein | Drosophila Proteins - metabolism | Neurodegenerative Diseases - drug therapy | PC12 Cells | Nerve Tissue Proteins - chemistry | Repetitive Sequences, Amino Acid | Peptides - metabolism | Acetylation | Huntington Disease - enzymology | Repressor Proteins - metabolism | Disease Models, Animal | Drosophila - genetics | Protein Structure, Tertiary | Huntington Disease - prevention & control | Enzyme Inhibitors - metabolism | Animals, Genetically Modified | CREB-Binding Protein | Gene Expression Regulation | Glutathione Transferase - metabolism | Rats | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | Neurodegenerative Diseases - metabolism | Nuclear Proteins - chemistry | Huntington Disease - metabolism | Nerve Tissue Proteins - metabolism | Huntingtin Protein | Animals | Saccharomyces cerevisiae Proteins | Trans-Activators - metabolism | Histone Deacetylase Inhibitors | Drosophila - metabolism | Drosophila Proteins - genetics | Histones - metabolism | Nerve Degeneration | Neurodegenerative Diseases - enzymology | Proteins | Amino acids | Insects | Disease
Journal Article
Journal Article