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Journal of Clinical Investigation, ISSN 0021-9738, 08/2017, Volume 127, Issue 8, pp. 2930 - 2940
Programmed death-1-directed (PD-1-directed) immune checkpoint blockade results in durable antitumor activity in many advanced malignancies. Recent studies... 
CELL LUNG-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | MELANOMA | PEMBROLIZUMAB | LIGANDS | IMMUNOTHERAPY | SAFETY | TOLERANCE | ADAPTIVE IMMUNE RESISTANCE | EXPRESSION | Immunohistochemistry | Lung Neoplasms - drug therapy | Skin Neoplasms - drug therapy | Humans | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Interferon-gamma - metabolism | Immune System | Carcinoma - drug therapy | Antibodies, Monoclonal, Humanized - therapeutic use | Signal Transduction | Skin Neoplasms - immunology | Carcinoma - immunology | Programmed Cell Death 1 Receptor - metabolism | Treatment Outcome | Stomach Neoplasms - drug therapy | Stomach Neoplasms - immunology | Carcinoma, Non-Small-Cell Lung - immunology | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Pilot Projects | Sequence Analysis, RNA | Biopsy | Melanoma - immunology | Melanoma - drug therapy | ROC Curve | Carcinoma, Non-Small-Cell Lung - drug therapy | PD-1 protein | Lung cancer | Clinical trials | Cytotoxicity | Biology | Lymphocytes T | Cancer therapies | Metastases | Lymphocytes | Neck | Adaptation | Antigen presentation | Squamous cell carcinoma | Cytokines | Melanoma | Inflammation | Gene expression | Immune checkpoint | PD-L1 protein | Head and neck cancer | Antitumor activity | Ligands | Interferon | Chemokines | Apoptosis | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 10/2017, Volume 190, Issue 1, pp. 122 - 132
Journal Article
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 03/2018, Volume 191, Issue 3, pp. 363 - 372
Blockade of the CD80/86‐CD28 pathway by belatacept after kidney transplantation is associated with an increased risk of rejection compared with standard,... 
co‐stimulation | T cells | cytotoxicity | transplantation | co-stimulation | ACTIVATION | TOLERANCE | IMMUNOLOGY | COSTIMULATION BLOCKADE | TRIAL | BELATACEPT | KIDNEY-TRANSPLANTATION | REJECTION | TACROLIMUS | EXPRESSION | EXHAUSTION | T-Lymphocytes, Cytotoxic - immunology | Graft Rejection - drug therapy | Kidney Failure, Chronic - immunology | Cell Proliferation | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Cells, Cultured | Programmed Cell Death 1 Receptor - metabolism | Male | Kidney Transplantation | Antigens, CD - metabolism | Kidney Failure, Chronic - therapy | Netherlands | Abatacept - therapeutic use | Isoantigens - immunology | Adult | Female | Aged | Graft Rejection - immunology | CD57 Antigens - metabolism | Cytotoxicity, Immunologic | Signaling Lymphocytic Activation Molecule Family - metabolism | Transplantation of organs, tissues, etc | Chronic kidney failure | Analysis | CD57 antigen | End-stage renal disease | Flow cytometry | PD-1 protein | Toxicity | CD8 antigen | Calcineurin | Calcineurin inhibitors | Fluorescence | Cytotoxicity | Stimulation | Leukocytes (mononuclear) | Transplantation | Lymphocytes T | CD223 antigen | CD28 antigen | Granzyme B | Lymphocytes | Peripheral blood mononuclear cells | Inhibition | CD80 antigen | Patients | CD4 antigen | Graft rejection | Rejection | Kidney diseases | Apoptosis | Kidney transplantation | Index Medicus | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e104639 - e104639
PCB 180 is a persistent non-dioxin-like polychlorinated biphenyl (NDL-PCB) abundantly present in food and the environment. Risk characterization of NDL-PCBs is... 
SUBCHRONIC TOXICITY | POLYCHLORINATED-BIPHENYLS PCBS | IN-VITRO | DIOXIN-LIKE-PCBS | ARYL-HYDROCARBON RECEPTOR | THYROID-HORMONE | MULTIDISCIPLINARY SCIENCES | EFFECT-DIRECTED ANALYSIS | DEVELOPMENTAL EXPOSURE | DIBENZO-P-DIOXINS | POSTNATAL EXPOSURE | Retinoids - metabolism | Environmental Pollutants - pharmacokinetics | Hematocrit | Body Weight - drug effects | Male | Luteinizing Hormone - metabolism | Dose-Response Relationship, Drug | Liver - drug effects | Thyroid Hormones - blood | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Female | Adrenal Cortex - drug effects | Environmental Pollutants - toxicity | Follicle Stimulating Hormone - metabolism | Liver - metabolism | Hemoglobins - metabolism | Rats | Rats, Sprague-Dawley | Animals | Polychlorinated Biphenyls - toxicity | Sex Factors | Polychlorinated Biphenyls - pharmacokinetics | DNA Damage | Adipose Tissue - drug effects | Pituitary hormones | Dioxin | Liver | Polychlorinated biphenyls | Hemoglobin | Glycoproteins | Thyroid hormones | Adipose tissue | Body weight | Hydrocarbons | Biochemistry | Thyroid gland | Hormones | Males | Toxicology | Gender aspects | Biphenyl | Luteinizing hormone | Physiology | Drug dosages | Deoxyribonucleic acid--DNA | Thyroid | Enzymes | Environmental health | Inhibition (psychology) | Sex differences | Risk taking | Anatomy & physiology | Metabolism | Gene expression | Body weight gain | PCB | Chemistry | Hypertrophy | Toxicity | DNA damage | Dioxins | Biology | Population levels | Human populations | PCB compounds | Metabolites | Environmental studies | Bones | Open-field behavior | Food | Medicine | Acids | Impurities | Polychlorinated biphenyls--PCB | Females | Index Medicus | Naturvetenskap | Natural Sciences | Kemi | Chemical Sciences | Deoxyribonucleic acid | DNA
Journal Article
BMC Genomics, ISSN 1471-2164, 04/2014, Volume 15, Issue 1, pp. 281 - 281
Background: Basic leucine zipper (bZIP) transcription factor gene family is one of the largest and most diverse families in plants. Current studies have shown... 
bZIP transcription factor family | Heat stress response | Gene expression | Drought response | Grapevine | ARABIDOPSIS-THALIANA | DNA-BINDING | BASIC REGION | NEGATIVE REGULATOR | SIGNAL-TRANSDUCTION | SHOOT APEX | BINDING FACTORS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | STRESS | LEUCINE-ZIPPER PROTEIN | RICE | Multigene Family | Genes, Plant | Transcriptome | Molecular Sequence Data | Gene Expression Profiling | Phylogeny | Vitis - classification | Organ Specificity - genetics | Droughts | Gene Expression Regulation, Developmental | Gene Expression Regulation, Plant | Conserved Sequence | Protein Interaction Domains and Motifs | Binding Sites | Gene Order | Vitis - genetics | Amino Acid Sequence | Computational Biology - methods | Genome-Wide Association Study | Reproducibility of Results | Stress, Physiological - genetics | Models, Molecular | Chromosome Mapping | Basic-Leucine Zipper Transcription Factors - genetics | Hot Temperature | Chromosomes, Plant | Basic-Leucine Zipper Transcription Factors - chemistry | Protein Binding | Protein Conformation | Cluster Analysis | Transcription factors | Grapes | Genetic research | Genetic aspects | Research | Identification and classification | Genes | Genomics | Amino acids | Genomes | DNA binding proteins | Plants | Arabidopsis thaliana | Evolution | Proteins | Data analysis | Abscisic acid | Phylogenetics | Software | Kinases | Bioinformatics | Salinity | Index Medicus
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 08/2018, Volume 138, Issue 8, pp. 1795 - 1804
Cutaneous CD30 lymphoproliferative disorders (LPDs), including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large-cell lymphoma, comprise the... 
PATHOGENESIS | LARGE-CELL LYMPHOMAS | TRANSLOCATIONS | DISEASE | IL-17 | GENE-EXPRESSION | ORGANIZER SATB1 | CLASSIFICATION | PROLIFERATION | TUMOR-GROWTH | DERMATOLOGY | Lymphoma, Large-Cell, Anaplastic - immunology | Up-Regulation | DNA Methylation - immunology | Skin Neoplasms - drug therapy | Follow-Up Studies | Humans | Middle Aged | Male | Th1 Cells - immunology | Promoter Regions, Genetic - genetics | Th1 Cells - metabolism | Lymphomatoid Papulosis - pathology | Th17 Cells - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Retrospective Studies | Child | Lymphomatoid Papulosis - drug therapy | Cytokines - immunology | Lymphoma, Large-Cell, Anaplastic - genetics | Skin Neoplasms - pathology | Cytokines - metabolism | Skin Neoplasms - immunology | Matrix Attachment Region Binding Proteins - metabolism | Lymphomatoid Papulosis - genetics | Gene Expression Regulation, Neoplastic - immunology | Treatment Outcome | Ki-1 Antigen - metabolism | Matrix Attachment Region Binding Proteins - immunology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Lymphoma, Large-Cell, Anaplastic - drug therapy | Skin Neoplasms - genetics | Lymphomatoid Papulosis - immunology | Cell Line, Tumor | Th17 Cells - immunology | Aged | Lymphoma, Large-Cell, Anaplastic - pathology | Biomarkers, Tumor - immunology
Journal Article
Journal Article