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Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 04/2017, Volume 172, pp. 73 - 100
Na 1.7, a subtype of the voltage-gated sodium channel family that is highly expressed in peripheral sensory neurons, remains one of the most promising targets... 
Paroxysmal extreme pain disorder | Inherited erythromelalgia | Sensory neuron | Sodium channel | Pain | Congenital insensitivity to pain
Journal Article
PHARMACOLOGY & THERAPEUTICS, ISSN 0163-7258, 04/2017, Volume 172, pp. 73 - 100
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 07/2017, Volume 60, Issue 14, pp. 5990 - 6017
Because of its strong genetic validation, Na(V)1.7 has attracted significant interest as a target for the treatment of pain. We have previously reported on a... 
MOLECULAR-MECHANISM | INACTIVATION | FIBRILLATION | RAT BILIARY-EXCRETION | NEUROPATHIC PAIN | ERYTHROMELALGIA | CHEMISTRY, MEDICINAL | DRUG DISCOVERY | EXTREME PAIN DISORDER | MUTATIONS | ANTAGONISTS
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 05/2015, Volume 172, Issue 10, pp. 2445 - 2458
Background and PurposeChronic pain is a serious worldwide health issue, with current analgesics having limited efficacy and dose-limiting side effects. Humans... 
PHARMACOLOGY | EXTREME PAIN DISORDER | NA-V | PHARMACOLOGY & PHARMACY | MUTATIONS | VOLTAGE-SENSOR | SODIUM-CHANNEL | HUWENTOXIN-IV | NUCLEOTIDE POLYMORPHISM | BINDING | PEPTIDE TOXINS
Journal Article