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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. E8131 - E8140
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2650 - 13
During development in the thymus, invariant natural killer T (iNKT) cells commit to one of three major functionally different subsets, iNKT1, iNKT2, and... 
EPITHELIAL-CELLS | GAMMA-DELTA T | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION PATTERNS | REGULATORY T-CELLS | INVARIANT NKT CELLS | RECEPTOR | LINEAGE DEVELOPMENT | SELECTION | TRANSCRIPTION FACTOR NFAT | FATE DECISIONS | T-Lymphocyte Subsets - immunology | Thymocytes - metabolism | Early Growth Response Protein 2 - genetics | Cell Differentiation - genetics | Signal Transduction - immunology | NFATC Transcription Factors - immunology | Natural Killer T-Cells - metabolism | Receptors, Antigen, T-Cell - immunology | Early Growth Response Protein 2 - immunology | Binding Sites | Receptors, Antigen, T-Cell - metabolism | Mice, Inbred C57BL | NFATC Transcription Factors - metabolism | Cells, Cultured | Gene Expression Profiling - methods | Mice, Transgenic | Signal Transduction - genetics | Thymocytes - immunology | Cell Differentiation - immunology | Animals | T-Lymphocyte Subsets - metabolism | Early Growth Response Protein 2 - metabolism | Thymocytes - cytology | Mice, Inbred BALB C | Receptors, Antigen, T-Cell - genetics | NFATC Transcription Factors - genetics | Natural Killer T-Cells - immunology | Chromatin | Accessibility | Signal strength | T cell receptors | Genomes | Lymphocytes T | Regulatory sequences | Gene expression | NF-AT protein | Thymus | T-cell receptor | Signaling | Lymphocytes | Egr-2 protein | Natural killer cells | Binding sites | Index Medicus
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2643 - 2650
Development of effective immune therapies for cancer patients requires better understanding of hurdles that prevent the generation of effective antitumor... 
MAMMALIAN TARGET | ACTIVATION | IMMUNOTHERAPY | IN-VIVO | QUIESCENCE | TUMOR-SUPPRESSOR TSC1 | NAIVE T-CELLS | INDUCTION | IMMUNOLOGY | CANCER | MTOR | Early Growth Response Protein 2 - genetics | Immunoblotting | Ubiquitin-Protein Ligases - immunology | Flow Cytometry | Melanoma, Experimental - immunology | Lung Neoplasms - secondary | Natural Killer T-Cells - metabolism | Tumor Suppressor Proteins - genetics | Gene Expression - immunology | Early Growth Response Protein 2 - immunology | Cytokines - immunology | Tuberous Sclerosis - immunology | Tumor Suppressor Proteins - metabolism | Natural Killer T-Cells - transplantation | Cytokines - metabolism | Immunotherapy, Adoptive | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Ubiquitin-Protein Ligases - metabolism | Homeostasis - immunology | Melanoma, Experimental - pathology | Programmed Cell Death 1 Receptor - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Tumor Suppressor Proteins - immunology | Mice, Knockout | Tuberous Sclerosis - genetics | Lung Neoplasms - immunology | Animals | Tuberous Sclerosis - metabolism | Cell Line, Tumor | Clonal Anergy - immunology | Early Growth Response Protein 2 - metabolism | Mice | Programmed Cell Death 1 Receptor - immunology | Ubiquitin-Protein Ligases - genetics | Programmed Cell Death 1 Receptor - genetics | Homeostasis - genetics | Natural Killer T-Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 11, pp. 4686 - 4699
A growing understanding of the bone remodeling process suggests that inflammation significantly contributes to the pathogenesis of osteoporosis. T cells and... 
B-CELLS | LOOP-HELIX PROTEINS | OSTEOBLAST | ACTIVATION | TR1 CELLS | INFLAMMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | OSTEOCLAST DIFFERENTIATION | TH17 | T-CELLS | Bone and Bones - pathology | Early Growth Response Protein 2 - genetics | Humans | Anti-Inflammatory Agents - immunology | Osteoporosis, Postmenopausal - pathology | Anti-Inflammatory Agents - metabolism | Bone and Bones - drug effects | Th17 Cells - drug effects | Osteoclasts - immunology | Bone and Bones - metabolism | Gene Deletion | Anti-Inflammatory Agents - therapeutic use | Estrogens - genetics | Female | Early Growth Response Protein 2 - immunology | Th17 Cells - pathology | Osteoclasts - pathology | Interleukin-27 - immunology | Osteoblasts - drug effects | RNA, Messenger - genetics | Cells, Cultured | Osteoblasts - immunology | Osteoporosis, Postmenopausal - genetics | Interleukin-27 - genetics | Osteoporosis, Postmenopausal - drug therapy | Up-Regulation - drug effects | Osteoblasts - pathology | Animals | Interleukin-27 - therapeutic use | Osteoporosis, Postmenopausal - immunology | Th17 Cells - immunology | Mice | Mice, Inbred BALB C | Bone and Bones - immunology | Interleukin-10 - immunology | Osteoclasts - drug effects | Index Medicus | Molecular Bases of Disease | immunosuppression | bone | osteoblast | osteoclast | osteoporosis | immunology
Journal Article
Immunity, ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 237 - 249
Interactions with antigen-presenting cells (APCs) interrupt T cell migration through tissues and trigger signaling pathways that converge on the activation... 
ACTIVATION | DENDRITIC CELLS | IN-VIVO | LYMPH-NODES | TUMOR | IMMUNOLOGY | IMMUNOLOGICAL SYNAPSE | STROMAL CELLS | CA2+ SIGNALS | STOP SIGNAL | CUTTING EDGE | Lymph Nodes - pathology | Early Growth Response Protein 2 - genetics | Humans | Receptors, Antigen, T-Cell | Antigen-Presenting Cells - pathology | Cell Nucleus - metabolism | NFATC Transcription Factors - immunology | T-Lymphocytes - metabolism | Cell Differentiation | Interferon-gamma - genetics | Tumor Cells, Cultured | Early Growth Response Protein 2 - immunology | Microscopy, Fluorescence, Multiphoton | Antigen-Presenting Cells - metabolism | Signal Transduction | Gene Expression Regulation | Cell Communication | Immune Tolerance | Lymph Nodes - metabolism | Lymph Nodes - immunology | Antigen-Presenting Cells - immunology | Protein Transport | Animals | Interferon-gamma - immunology | Cytosol - metabolism | Immunologic Memory | T-Lymphocytes - immunology | Mice | Cell Movement | NFATC Transcription Factors - genetics | T cells | Antigens | Proteins | Signal transduction | Peptides | Quantum dots | Cytotoxicity | Gene expression | Immune system | Index Medicus | Nuclear Factor of Activated T cells (NFAT) | T Regulatory Cells (T reg) | Gene Expression | Antigen Presenting Cells (APC) | Tumor Microenvironment | Cytotoxic T Lymphocytes (CTL) | Lymph Node (LN) | Transcriptional Regulation | Multiphoton Intravital Microscopy (MP-IVM) | Signal Memory
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 05/2017, Volume 101, Issue 5, pp. 1221 - 1231
Antigen specificity to enhance immune suppression by nonspecific polyclonal CD8 + 25 + Tr‐cells can be achieved through exosomal pMHC arming. Compared with CD4... 
exosomal arming | 25 | dendritic cells | T | CD8 | pMHC complex | regs | CTL | + | Tregs, CTL | PMHC complex | Dendritic cells | Exosomal arming | TGF-BETA | CTL RESPONSES | IMMUNOLOGY | CUTTING EDGE | CELL BIOLOGY | IN-VIVO | CD8(+)25(+) T-regs | MEDIATED SUPPRESSION | ANTITUMOR IMMUNITY | HEMATOLOGY | AUTOIMMUNE-DISEASE | GRANZYME-B | SELF-TOLERANCE | Neoplasm Transplantation | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Cell Proliferation | Lung Neoplasms - mortality | Dendritic Cells - immunology | Early Growth Response Protein 2 - genetics | Clonal Anergy | Dendritic Cells - pathology | Lung Neoplasms - pathology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Cytotoxic - pathology | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Cytotoxic - drug effects | Interleukin-2 - immunology | Exosomes - immunology | Dendritic Cells - drug effects | B7-2 Antigen - immunology | Early Growth Response Protein 2 - immunology | Lung Neoplasms - genetics | T-Lymphocytes, Cytotoxic - immunology | Transforming Growth Factor beta - immunology | Signal Transduction | B7-1 Antigen - immunology | Lymphocyte Activation | Mice, Inbred C57BL | Gene Expression Regulation | Histocompatibility Antigens Class I - immunology | CTLA-4 Antigen - genetics | Histocompatibility Antigens Class I - genetics | CTLA-4 Antigen - immunology | Ovalbumin - pharmacology | Mice, Knockout | Interleukin-2 - genetics | Lung Neoplasms - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Transforming Growth Factor beta - genetics | Interleukin-10 - genetics | Survival Analysis | Exosomes - chemistry | Mice | Primary Cell Culture | Interleukin-10 - immunology | Cytotoxicity, Immunologic | Cell proliferation | CD86 antigen | Anergy | CD8 antigen | Lung cancer | Cytotoxicity | Stimulation | Lymphocytes T | Exosomes | Immunity | CTLA-4 protein | Interleukin 2 | Lymphocytes | Immunotherapy | Egr-2 protein | Perforin | Antigens | Ovalbumin | Cytokines | Immunoregulation | Priming | CD80 antigen | Inflammation | T cell receptors | CD4 antigen | Immune systems | Immunosuppression | Major histocompatibility complex | Interleukin 10 | Degranulation | Autoimmune diseases | Auditory defects | Cancer | Apoptosis
Journal Article