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1. Full Text Investigating Ebola virus pathogenicity using molecular dynamics
by Pappalardo, Morena and Collu, Francesca and Macpherson, James and Michaelis, Martin and Fraternali, Franca and Wass, Mark N
BMC Genomics, ISSN 1471-2164, 2017, Volume 18, Issue Suppl 5, pp. 566 - 45
Background: Ebolaviruses have been known to cause deadly disease in humans for 40 years and have recently been demonstrated in West Africa to be able to cause... 
Pathogenicity | Molecular dynamics | Ebola | Protein structure | Virology | PROTEIN SECONDARY STRUCTURE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | DIFFERENT FORCE-FIELDS | KARYOPHERIN | SOLVATION | HYDRATION | alpha Karyopherins - metabolism | Ebolavirus - metabolism | Viral Proteins - chemistry | Humans | Ebolavirus - pathogenicity | Protein Conformation | Viral Proteins - metabolism | Hemorrhagic Fever, Ebola - metabolism | Molecular Dynamics Simulation | Ebola virus | Proteins | Research | Structure | Analysis | Binding | Dynamic structural analysis | VP24 protein | Pathogens | Epidemics | Water chemistry | Hydration | Viral diseases | Amino acid sequence | Viruses | Amino acids | Outbreaks | Studies | Signaling | Interferon | Mutation | Bioinformatics | Structural analysis
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2. Full Text Replication, Pathogenicity, Shedding, and Transmission of Zaire ebolavirus in Pigs
by Gary P. Kobinger and Anders Leung and James Neufeld and Jason S. Richardson and Darryl Falzarano and Greg Smith and Kevin Tierney and Ami Patel and Hana M. Weingartl
The Journal of Infectious Diseases, ISSN 0022-1899, 7/2011, Volume 204, Issue 2, pp. 200 - 208
Background. Reston ebolavirus was recently detected in pigs in the Philippines. Specific antibodies were found in pig farmers, indicating exposure to the... 
Ebola virus | Pulmonary alveoli | Disease transmission | Animals | Lungs | Swine | Humans | Primates | Viruses | Infections | INFECTIOUS DISEASES | VIRUS-INFECTION | FILOVIRUS | MICROBIOLOGY | IMMUNOLOGY | DISCOVERY | PATHOGENESIS | PHILIPPINES | HEMORRHAGIC-FEVER | IN-VIVO | MACAQUES | MONKEYS | TRANSDUCE AIRWAY EPITHELIA | Lung - pathology | Swine Diseases - virology | Swine Diseases - pathology | Ebolavirus - pathogenicity | Hemorrhagic Fever, Ebola - transmission | Ebolavirus - growth & development | Virus Shedding | Hemorrhagic Fever, Ebola - pathology | Hemorrhagic Fever, Ebola - veterinary | Respiratory System - virology | Swine Diseases - transmission | Virus Replication | Mouth Mucosa - virology | Hemorrhagic Fever, Ebola - virology | Nasal Mucosa - virology | Ebola virus infections | Development and progression | Research | Health aspects
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3. Full Text Ebolaviruses associated with differential pathogenicity induce distinct host responses in human macrophages
by Olejnik, Judith and Forero, Adriana and Deflubé, Laure R and Hume, Adam J and Manhart, Whitney A and Nishida, Andrew and Marzi, Andrea and Katze, Michael G and Ebihara, Hideki and Rasmussen, Angela L and Mühlberger, Elke
Journal of Virology, ISSN 0022-538X, 06/2017, Volume 91, Issue 11
Ebola virus (EBOV) and Reston virus (RESTV) are members of the Ebolavirus genus which greatly differ in their pathogenicity. While EBOV causes a severe disease... 
Ebola virus | Host response | Cytokines | Interferons | Toll-like receptor 4 | Toll-like receptors | Filovirus | Macrophages | Reston virus | Chemokines | RESTON-EBOLAVIRUS | TOLL-LIKE RECEPTOR | TLR4-MD-2 COMPLEX | EBOLA-VIRUS INFECTION | chemokines | filovirus | FILOVIRUS INFECTION | host response | SIGNAL-TRANSDUCTION | macrophages | INTERFERON RESPONSE | interferons | VIROLOGY | HEMORRHAGIC-FEVER | cytokines | PATTERN-RECOGNITION RECEPTORS | NF-KAPPA-B | Dendritic Cells - immunology | Humans | Virulence | Cercopithecus aethiops | Ebolavirus - pathogenicity | Gene Expression Profiling | NF-kappa B p50 Subunit - genetics | Interferons - immunology | Interferon Regulatory Factor-3 - genetics | Ebolavirus - immunology | Macrophages - virology | Dendritic Cells - virology | Vero Cells | Macrophages - immunology | Chemokines - immunology | Cytokines - immunology | Interferon Regulatory Factor-3 - immunology | Cell Line | NF-kappa B p50 Subunit - metabolism | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 4 - metabolism | Host-Pathogen Interactions | Macrophages - metabolism | Animals | Chemokines - metabolism | Ebolavirus - physiology
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4. Full Text Pathogenicity Comparison between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques
by Wong, Gary and Qiu, Xiangguo and De La Vega, Marc-Antoine and Fernando, Lisa and Wei, Haiyan and Bello, Alexander and Fausther-Bovendo, Hugues and Audet, Jonathan and Kroeker, Andrea and Kozak, Robert and Tran, Kaylie and He, Shihua and Tierney, Kevin and Soule, Geoff and Moffat, Estella and Günther, Stephan and Gao, George F and Strong, Jim and Embury-Hyatt, Carissa and Kobinger, Gary
Journal of Infectious Diseases, ISSN 0022-1899, 10/2016, Volume 214, Issue suppl 3, pp. S281 - S289
Enhanced virulence and/or transmission of West African Ebola virus (EBOV) variants, which are divergent from their Central African counterparts, are suspected... 
Ebola virus | Kikwit | Pathogenicity | Makona | Nonhuman primates | NONHUMAN-PRIMATES | INFECTIOUS DISEASES | CYNOMOLGUS MACAQUES | SARS | MICROBIOLOGY | nonhuman primates | IMMUNOLOGY | pathogenicity | TRANSMISSION | HEMORRHAGIC-FEVER | DISEASE | INFECTION | OUTBREAK | STRAIN | Animals | Species Specificity | Viremia | Hemorrhagic Fever, Ebola - virology | Humans | Virulence | Ebolavirus - pathogenicity | Macaca mulatta | Virus Shedding | Hemorrhagic Fever, Ebola - pathology | Ebolavirus - physiology | Ebola Outbreak in West Africa
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5. Full Text RNA Editing of the GP Gene of Ebola Virus is an Important Pathogenicity Factor
by Volchkova, VA and Dolnik, O and Martinez, MJ and Reynard, O and Volchkov, VE
JOURNAL OF INFECTIOUS DISEASES, ISSN 0022-1899, 10/2015, Volume 212, Issue suppl 2, pp. S226 - S233
Synthesis of the surface glycoprotein GP of Ebola virus ( EBOV) is dependent on transcriptional RNA editing, whereas direct expression of the GP gene results... 
glycoprotein GP | INFECTIOUS DISEASES | RNA editing | SMALL GLYCOPROTEIN SGP | DETERMINANT | MICROBIOLOGY | GUINEA-PIGS | IMMUNOLOGY | IDENTIFICATION | Ebola virus | pathogenicity | INFECTION | editing site | CYTOTOXICITY | DELTA-PEPTIDE | Cell Line | Viral Envelope Proteins - genetics | Guinea Pigs | Virulence Factors - genetics | RNA Editing - genetics | Viral Proteins - genetics | Ebolavirus - pathogenicity | Gene Expression Regulation, Viral - genetics | Ebolavirus - genetics | Mutation - genetics | Down-Regulation - genetics | Membrane Glycoproteins - genetics | Animals | Genes, Viral - genetics | Hemorrhagic Fever, Ebola - virology | Life Sciences | Microbiology and Parasitology | Immunology | Bacteriology | Virology
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6. Full Text Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses
by Pappalardo, Morena and Julia, Miguel and Howard, Mark J and Rossman, Jeremy S and Michaelis, Martin and Wass, Mark N
Scientific Reports, ISSN 2045-2322, 03/2016, Volume 6, Issue 1, pp. 23743 - 23743
Reston viruses are the only Ebolaviruses that are not pathogenic in humans. We analyzed 196 Ebolavirus genomes and identified specificity determining positions... 
TRANSMISSION | EBOLA-VIRUS VP35 | VP24 PROTEINS | EVOLUTION | RNA | RESTON-EBOLAVIRUS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | GLYCOPROTEIN | VIRULENCE | GENOME | alpha Karyopherins - metabolism | Ebolavirus - metabolism | Viral Matrix Proteins - genetics | Virulence Factors - genetics | Swine Diseases - virology | Humans | Ebolavirus - pathogenicity | Phylogeny | Ebolavirus - genetics | Viral Proteins - metabolism | Genetic Variation | Swine | Conserved Sequence | Viral Matrix Proteins - metabolism | Amino Acid Sequence | Viral Proteins - chemistry | Models, Molecular | Viral Proteins - genetics | Hemorrhagic Fever, Ebola - transmission | Host Specificity | Hemorrhagic Fever, Ebola - veterinary | Swine Diseases - transmission | Animals | Viral Matrix Proteins - chemistry | Protein Conformation | Virulence Factors - metabolism | Pathogenicity | Proteins | VP24 protein | Conserved sequence | VP40 protein | Amino acid sequence | Viruses | Interferon | Genomes | Hydrophobicity | Index Medicus
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7. Full Text Transmissibility and pathogenicity of Ebola virus: A systematic review and meta-analysis of household secondary attack rate and asymptomatic infection
by Dean, Natalie E and Halloran, M. Elizabeth and Yang, Yang and Longini, Ira M
Clinical Infectious Diseases, ISSN 1058-4838, 05/2016, Volume 62, Issue 10, pp. 1277 - 1286
Factors affecting our ability to control an Ebola outbreak include transmissibility of the virus and the proportion of transmissions occurring... 
asymptomatic infection | household | Ebola | secondary attack rate | VIRAL LOAD | ANTIBODIES | DIAGNOSIS | INFECTIOUS DISEASES | RISK-FACTORS | MICROBIOLOGY | IMMUNOLOGY | UGANDA | HEMORRHAGIC-FEVER | KIKWIT | DISEASE | OUTBREAK | CONGO | Asymptomatic Infections | Family Characteristics | Hemorrhagic Fever, Ebola - virology | Humans | Ebolavirus - pathogenicity | Hemorrhagic Fever, Ebola - transmission | Disease Outbreaks - statistics & numerical data | Hemorrhagic Fever, Ebola - epidemiology | Ebola virus infections | Care and treatment | Usage | Nursing care | Management | Meta-analysis | Review
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8. Full Text Infectious Lassa Virus, but Not Filoviruses, Is Restricted by BST-2/Tetherin
by Sheli R. Radoshitzky and Lian Dong and Xiaoli Chi and Jeremiah C. Clester and Cary Retterer and Kevin Spurgers and Jens H. Kuhn and Sarah Sandwick and Gordon Ruthel and Krishna Kota and Dutch Boltz and Travis Warren and Philip J. Kranzusch and Sean P. J. Whelan and Sina Bavari
Journal of Virology, ISSN 0022-538X, 10/2010, Volume 84, Issue 20, pp. 10569 - 10580
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
INTERFERON RESPONSE | IN-VITRO | HUMAN DENDRITIC CELLS | VIROLOGY | PROTEIN SORTING PATHWAY | MATRIX PROTEIN | VALLEY FEVER VIRUS | NIPAH-VIRUS | SIGNAL PEPTIDE | ZAIRE EBOLAVIRUS | EBOLA-VIRUS | RNA, Small Interfering - genetics | Nipah Virus - pathogenicity | Humans | Arenaviruses, New World - genetics | Ebolavirus - pathogenicity | Marburgvirus - pathogenicity | Ebolavirus - genetics | Antigens, CD - genetics | Gene Knockdown Techniques | Membrane Glycoproteins - physiology | Filoviridae - genetics | Transfection | Base Sequence | Arenaviruses, New World - pathogenicity | Filoviridae - physiology | GPI-Linked Proteins - antagonists & inhibitors | Filoviridae - pathogenicity | Cell Line | Marburgvirus - physiology | Lassa virus - genetics | Marburgvirus - genetics | Membrane Glycoproteins - genetics | Lassa virus - pathogenicity | Lassa virus - physiology | Nipah Virus - physiology | Animals | Nipah Virus - genetics | Virus Release - physiology | GPI-Linked Proteins - physiology | Antigens, CD - physiology | Arenaviruses, New World - physiology | Mice | HeLa Cells | DNA, Viral - genetics | Ebolavirus - physiology | GPI-Linked Proteins - genetics | Host-Pathogen Interactions - physiology | Virus-Cell Interactions
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9. Transmission, human population, and pathogenicity: The ebola case in point
by Delgado, Rafael and Simón, Fernando
Microbiology Spectrum, ISSN 2165-0497, 03/2018, Volume 6, Issue 2
The 2013-2016 Ebola outbreak in West Africa has been the largest ever of a known disease in a new context that produced an unprecedented impact and is changing... 
NONHUMAN-PRIMATES | UNITED-STATES | MARBURG VIRUS | WEST-AFRICA | HEMORRHAGIC-FEVER | SIERRA-LEONE | DISEASE | ZAIRE | SUBTYPE RESTON VIRUS | MICROBIOLOGY | EPIDEMIOLOGY | Public Health | Hemorrhagic Fever, Ebola - prevention & control | History, 21st Century | Humans | Virulence | Emergencies | Ebolavirus - pathogenicity | Hemorrhagic Fever, Ebola - transmission | Ebolavirus - genetics | Hemorrhagic Fever, Ebola - epidemiology | Disease Transmission, Infectious - prevention & control | Disease Outbreaks - history | Africa, Western - epidemiology | Hemorrhagic Fever, Ebola - therapy | Delivery of Health Care | Epidemics - prevention & control | Disease Outbreaks - prevention & control
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10. Full Text Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice
by Gabriel, Gülsah and Feldmann, Friederike and Reimer, Rudolph and Thiele, Swantje and Fischer, Meike and Hartmann, Enno and Bader, Michael and Ebihara, Hideki and Hoenen, Thomas and Feldmann, Heinz
Journal of Infectious Diseases, ISSN 0022-1899, 10/2015, Volume 212, Issue suppl 2, pp. S316 - S321
Ebola virus (EBOV) protein 24 antagonizes the host interferon (IFN) response by hijacking select nuclear importin-α isoforms. Thereby, it blocks STAT1-mediated... 
Ebola virus | pathogenicity | VP24 | STAT1 | importin-α | inclusion bodies | interferon | Inclusion Bodies, Viral - physiology | alpha Karyopherins - metabolism | Cell Line | Ebolavirus - metabolism | Virus Replication - genetics | Mice, Inbred C57BL | Cercopithecus aethiops | Ebolavirus - pathogenicity | Ebolavirus - genetics | Viral Proteins - metabolism | Animals | Virulence - genetics | Hemorrhagic Fever, Ebola - virology | DNA Replication - genetics | Virulence - physiology | Mice | Vero Cells | Hemorrhagic Fever, Ebola - metabolism | Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
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11. Full Text Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity
by Dowall, Stuart D and Matthews, David A and Garcia-Dorival, Isabel and Taylor, Irene and Kenny, John and Hertz-Fowler, Christiane and Hall, Neil and Corbin-Lickfett, Kara and Empig, Cyril and Schlunegger, Kyle and Barr, John N and Carroll, Miles W and Hewson, Roger and Hiscox, Julian A
Genome biology, ISSN 1474-760X, 2014, Volume 15, Issue 11, pp. 540 - 540
Background Ebolaviruses causes a severe and often fatal hemorrhagic fever in humans, with some species such as Ebola virus having case fatality rates... 
PATHOGENESIS | TRANSMISSION | REPLICATION | VP24 | RNA | HEMORRHAGIC-FEVER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ZAIRE | ADAPTATION | GENETICS & HEREDITY | INFECTION | GUINEA-PIGS | Animals | Guinea Pigs | RNA Editing - genetics | Hemorrhagic Fever, Ebola - virology | Humans | Viral Proteins - genetics | Ebolavirus - pathogenicity | Hemorrhagic Fever, Ebola - genetics | Ebolavirus - genetics | Sequence Analysis, DNA | Disease Models, Animal | Research
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12. Full Text Role of EXT1 and glycosaminoglycans in the early stage of filovirus entry
by O'Hearn, Aileen and Wang, Minxiu and Cheng, Han and Lear-Rooney, Calli M and Koning, Katie and Rumschlag-Booms, Emily and Varhegyi, Elizabeth and Olinger, Gene and Rong, Lijun
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 10, pp. 5441 - 5449
Filoviruses, including both Ebola virus (EBOV) and Marburg virus (MARV), can infect humans and other animals, causing hemorrhagic fever with a high mortality... 
HERPES-SIMPLEX-VIRUS | VIROLOGY | HEMORRHAGIC-FEVER | CELLULAR ENTRY | ZAIRE-EBOLAVIRUS | E2 GLYCOPROTEIN | REQUIRES | HEPARAN-SULFATE | MARBURG | BINDING | EBOLA-VIRUS | Heparitin Sulfate - biosynthesis | Humans | Virulence | N-Acetylglucosaminyltransferases - genetics | Ebolavirus - pathogenicity | Filoviridae Infections - etiology | Marburgvirus - pathogenicity | Virus Internalization | Gene Knockdown Techniques | Receptors, Virus - physiology | Heparin - physiology | HEK293 Cells | Viral Proteins - physiology | Filoviridae - physiology | Filoviridae - pathogenicity | Cell Line | Marburgvirus - physiology | Host-Pathogen Interactions | Glycosaminoglycans - physiology | Animals | Filoviridae Infections - virology | N-Acetylglucosaminyltransferases - antagonists & inhibitors | N-Acetylglucosaminyltransferases - physiology | Mice | Heparitin Sulfate - deficiency | Ebolavirus - physiology
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13. Ebola
: the natural and human history of a deadly virus
by Quammen, David
2014, ISBN 9780393351552, 119
Ebola virus | Epidemics | pathogenicity | Disease Outbreaks | Hemorrhagic Fever, Ebola | Disease Reservoirs | History | Ebola virus disease
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14. Ebola virus disease
: from origin to outbreak
by Qureshi, Adnan I
2016, ISBN 9780128042304
"Ebola Virus Disease: From Origins to Outbreak covers the symptoms, treatments, origins, and major outbreaks of the Ebola virus, both past and present. It... 
Ebolavirus | Epidemics | pathogenicity | Hemorrhagic Fever, Ebola | history | Epidemiology | Ebola virus disease
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15. Full Text Lessons from reservoirs
by Willyard, C
Nature Medicine, ISSN 1078-8956, 08/2017, Volume 23, Issue 8, pp. 899 - 903
MEDICINE, RESEARCH & EXPERIMENTAL | CRISPR | METHYLATION | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPRESSION | GENOME | CELL BIOLOGY | HIV - physiology | Host-Parasite Interactions - physiology | Disease Reservoirs - virology | Humans | Zika Virus - physiology | Ebolavirus - pathogenicity | HIV - pathogenicity | Ebolavirus - physiology | Skin - virology | Zika Virus - pathogenicity
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16. Full Text Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses
by Martines, Roosecelis Brasil and Ng, Dianna L and Greer, Patricia W and Rollin, Pierre E and Zaki, Sherif R
The Journal of Pathology, ISSN 0022-3417, 01/2015, Volume 235, Issue 2, pp. 153 - 174
Ebola viruses and Marburg viruses include some of the most virulent and fatal pathogens known to humans. These viruses cause severe haemorrhagic fevers, with... 
Ebola virus | pathogenesis | pathology | Marburg virus | haemorrhagic fever | electron microscopy | immunohistochemistry | filovirus | autopsy | Haemorrhagic fever | Immunohistochemistry | Pathology | Autopsy | Pathogenesis | Filovirus | Electron microscopy | VIRAL HEMORRHAGIC-FEVER | DENDRITIC CELLS | CYNOMOLGUS MACAQUES | ELECTRON-MICROSCOPY | GUINEA-PIGS | ACUTE RESPIRATORY SYNDROME | NIEMANN-PICK C1 | FILOVIRUS ENTRY | ONCOLOGY | DC-SIGN | RHESUS MACAQUES | Predictive Value of Tests | Prognosis | Marburg Virus Disease - immunology | Marburg Virus Disease - virology | Humans | Virulence | Ebolavirus - pathogenicity | Marburgvirus - pathogenicity | Ebolavirus - genetics | Ebolavirus - immunology | Virus Internalization | Hemorrhagic Fever, Ebola - diagnosis | Hemorrhagic Fever, Ebola - virology | Marburgvirus - immunology | Pathology, Molecular - methods | Hemorrhagic Fever, Ebola - immunology | Viral Tropism | Marburg Virus Disease - epidemiology | Marburg Virus Disease - pathology | Risk Factors | Hemorrhagic Fever, Ebola - transmission | Hemorrhagic Fever, Ebola - pathology | Hemorrhagic Fever, Ebola - epidemiology | Virology - methods | Ebolavirus - isolation & purification | Marburg Virus Disease - transmission | Marburgvirus - genetics | Host-Pathogen Interactions | Animals | Biopsy | Marburgvirus - isolation & purification | Marburg Virus Disease - diagnosis | Virulence (Microbiology) | Health aspects | Marburg virus disease
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