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1. Full Text Efficacy of a single dose of milbemycin oxime/praziquantel combination tablets, Milpro®, against adult Echinococcus multilocularis in dogs and both adult and immature E. multilocularis in young cats
by Cvejic, Dejan and Schneider, Claudia and Fourie, Josephus and de Vos, Christa and Bonneau, Stephane and Bernachon, Natalia and Hellmann, Klaus
Parasitology Research, ISSN 0932-0113, 3/2016, Volume 115, Issue 3, pp. 1195 - 1202
Two single-site, laboratory, negatively controlled, masked, randomised dose confirmation studies were performed: one in dogs, the other in cats. After a period... 
Medical Microbiology | Cats | Milpro | Biomedicine | Immunology | Echinococcus | Microbiology | Milbemycin | Praziquantel | Dogs | E. multilocularis | FOXES | ALVEOLAR HYDATID-DISEASE | Milpro (R) | OXIME | PARASITOLOGY | Macrolides - administration & dosage | Echinococcosis - veterinary | Parasite Load | Echinococcus multilocularis - physiology | Cat Diseases - drug therapy | Male | Treatment Outcome | Animals | Dog Diseases - drug therapy | Echinococcosis - drug therapy | Female | Praziquantel - administration & dosage | Drug Combinations | Index Medicus | Original Paper
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2. Full Text The prevalence of Echinococcus multilocularis in red foxes in Poland—current results (2009–2013)
by Karamon, Jacek and Kochanowski, Maciej and Sroka, Jacek and Cencek, Tomasz and Różycki, Mirosław and Chmurzyńska, Ewa and Bilska-Zając, Ewa
Parasitology Research, ISSN 0932-0113, 1/2014, Volume 113, Issue 1, pp. 317 - 322
The aim of the study was to determine the prevalence of Echinococcus multilocularis in red foxes (Vulpes vulpes) in Poland. Overall, 1,546 intestinal samples... 
Medical Microbiology | Biomedicine | Immunology | Microbiology | ALVEOLAR ECHINOCOCCOSIS | CESTODA | VULPES-VULPES | SWITZERLAND | TAPEWORM | PARASITOLOGY | Echinococcus multilocularis - isolation & purification | Animals | Prevalence | Echinococcosis - veterinary | Echinococcosis - epidemiology | Intestines - parasitology | Foxes - parasitology | Poland - epidemiology | Biological research | Physiological aspects | Host-parasite relationships | Red fox | Research | Sporozoa | Health aspects | Prevalence studies (Epidemiology) | Biology, Experimental | Index Medicus | Original Paper
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3. Full Text Westward spread of Echinococcus multilocularis in Foxes, France, 2005-2010
by Combes, Benoît and Comte, Sébastien and Raton, Vincent and Raoul, Francis and Boué, Franck and Umhang, Gérald and Favier, Stéphanie and Dunoyer, Charlotte and Woronoff, Natacha and Giraudoux, Patrick
Emerging Infectious Diseases, ISSN 1080-6040, 12/2012, Volume 18, Issue 12, pp. 2059 - 2062
During 2005-2010, we investigated Echinococcus multilocularis infection within fox populations in a large area in France. The parasite is much more widely... 
ALVEOLAR ECHINOCOCCOSIS | INFECTIOUS DISEASES | IMMUNOLOGY | Echinococcus multilocularis | France - epidemiology | Animals | Prevalence | Echinococcosis - veterinary | Seasons | Foxes - parasitology | Care and treatment | Foxes | Diagnosis | Methods | Echinococcosis | Diseases | Prevalence studies (Epidemiology) | Index Medicus | Life Sciences | Ecology, environment | Health | Environmental Sciences | Global Changes | prevalence | disease | Vulpes | Europe | Dispatch | human alveolar echinococcosis | parasites | zoonoses | France | Cestode parasite | Echinococcus multilocularis transmission | fox | Cestod parasite
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4. Full Text Upregulation of PD-1 on CD4+CD25+T cells is associated with immunosuppression in liver of mice infected with Echinococcus multilocularis
by La, Xiaolin and Zhang, Fengbo and Li, Yanhua and Li, Jun and Guo, Yuyuan and Zhao, Hui and Pang, Nannan and Ma, Xiumin and Wen, Hao and Fan, Haining and Ding, Jianbing
International Immunopharmacology, ISSN 1567-5769, 06/2015, Volume 26, Issue 2, pp. 357 - 366
Alveolar echinococcosis is a zoonotic disease caused by ( ) infection. The relationship between PD-1/PD-L1 pathway and Tregs at different stages of infection... 
Infection | PD-L1 | Echinococcus multilocularis | PD-1 | Tregs | CHRONIC HEPATITIS-B | TREG | PROGRAMMED DEATH 1 | IMMUNOLOGY | IMMUNE | PATHWAY | FREQUENCY | PHARMACOLOGY & PHARMACY | BLOCKADE | EXPRESSION | T-CELLS | EXHAUSTION | Up-Regulation | Dendritic Cells - parasitology | Cell Proliferation | Dendritic Cells - immunology | Cells, Cultured | Echinococcosis - immunology | Immune Tolerance | Programmed Cell Death 1 Receptor - metabolism | T-Lymphocytes, Regulatory - immunology | B7-H1 Antigen - metabolism | Liver - immunology | Animals | Immune Evasion | Interleukin-2 Receptor alpha Subunit - metabolism | Echinococcus multilocularis - immunology | Interleukin-10 - metabolism | Mice | Mice, Inbred BALB C | Liver - parasitology | T-Lymphocytes, Regulatory - parasitology | Programmed Cell Death 1 Receptor - genetics | Transforming Growth Factor beta - metabolism | Index Medicus
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5. Full Text Echinococcus multilocularis infection, Southern Ontario, Canada
by Kotwa, Jonathon D and Kotwa, Jonathon D and Isaksson, Mats and Isaksson, Mats and Jardine, Claire M and Jardine, Claire M and Campbell, G Douglas and Campbell, G. Douglas and Berke, Olaf and Berke, Olaf and Pearl, David L and Pearl, David L and Mercer, Nicola J and Mercer, Nicola J and Osterman-Lind, Eva and Osterman-Lind, Eva and Peregrine, Andrew S and Peregrine, Andrew S
Emerging Infectious Diseases, ISSN 1080-6040, 02/2019, Volume 25, Issue 2, pp. 265 - 272
Alveolar echinococcosis, the disease caused by infection with the intermediate stage of the Echinococcus multilocularis tapeworm, is typically fatal in humans... 
zoonoses | alveolar echinococcosis | Canis latrans | distribution | foxes | coyotes | Canada | Echinococcus multilocularis | prevalence | dogs | parasites | wild canids | cestodes | Ontario | public health | southern Ontario | Vulpes vulpes | INFECTIOUS DISEASES | PUBLIC-HEALTH | ALVEOLAR HYDATID-DISEASE | FOLLOW-UP | RISK | IMMUNOLOGY | DOG | Infection | Medicine, Experimental | Medical research | Health aspects | Southern Ontario, Canada | Research | cestode | parasite | zoonosis
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6. Full Text Successful intestinal Echinococcus multilocularis oncosphere invasion and subsequent hepatic metacestode establishment in resistant RccHan™: WIST rats after pharmacological immunosuppression
by Armua-Fernandez, Maria Teresa and Joekel, Deborah and Schweiger, Alexander and Eichenberger, Ramon Marc and Matsumoto, Jun and Deplazes, Peter
Parasitology, ISSN 0031-1820, 09/2016, Volume 143, Issue 10, pp. 1252 - 1260
Susceptibility/resistance to larval Echinococcus multilocularis infection varies greatly depending on host species and strains. Whereas several mice strains... 
Echinococcus multilocularis | immunosuppression | metacestode | alveolar echinococcosis | rat | resistance | RHEUMATOID-ARTHRITIS | HOKKAIDO | METHOTREXATE | TRANSMISSION | LIVER | INFECTION | RATTUS-NORVEGICUS | PARASITE | HIGH PREVALENCE | PARASITOLOGY | Echinococcus multilocularis - isolation & purification | Dexamethasone - administration & dosage | Disease Resistance | Rats, Wistar | Echinococcosis - immunology | Rats | Rats, Nude | Immunosuppression | Animals | Echinococcus multilocularis - pathogenicity | Echinococcosis, Hepatic - parasitology | Echinococcus multilocularis - immunology | Intestines - parasitology | Methotrexate - administration & dosage | T-Lymphocytes - immunology | Ovum | Echinococcosis - parasitology | Immunosuppressive Agents - administration & dosage | Disease Models, Animal | Index Medicus
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7. Full Text Foxp3+ T regulatory cells as a potential target for immunotherapy against primary infection with echinococcus multilocularis eggs
by Wang, Junhua and Cardoso, Rita and Marreros, Nelson and Müller, Norbert and Lundström-Stadelmann, Britta and Siffert, Myriam and Vuitton, Dominique A and Boue, Franck and Lin, Renyong and Wen, Hao and Gottstein, Bruno
Infection and Immunity, ISSN 0019-9567, 10/2018, Volume 86, Issue 10
Alveolar echinococcosis (AE) is a lethal disease caused by infection with the metacestode stage of the helminth Echinococcus multilocularis, which develops... 
Treg deficiency | Th1 immunity | Alveolar echinococcosis | Regulatory T cells | Oral infection | IMMUNITY | INFECTIOUS DISEASES | INOCULATION | METACESTODE | DEPLETION | CYTOKINE | alveolar echinococcosis | IMMUNOLOGY | oral infection | BLOOD MONONUCLEAR-CELLS | regulatory T cells | RESPONSES | CHEMOKINE RELEASE | PATHWAY | Forkhead Transcription Factors - immunology | Echinococcosis - therapy | Humans | Th2 Cells - immunology | Th1 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Immunotherapy | Female | Ovum - immunology | Interferon-gamma - genetics | Interleukin-4 - genetics | Cytokines - genetics | Chemokines - immunology | Cytokines - immunology | Mice, Inbred C57BL | Echinococcosis - immunology | Forkhead Transcription Factors - genetics | Chemokines - genetics | Interleukin-4 - immunology | Animals | Interferon-gamma - immunology | Echinococcus multilocularis - immunology | Mice | Echinococcosis - parasitology | Echinococcus multilocularis - genetics | Index Medicus
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8. Full Text Echinococcus multilocularis in urban coyotes, Alberta, Canada
by Catalano, Stefano and Lejeune, Manigandan and Liccioli, Stefano and Verocai, Guilherme G and Gesy, Karen M and Jenkins, Emily J and Kutz, Susan J and Fuentealba, Carmen and Duignan, Padraig J and Massolo, Alessandro
Emerging Infectious Diseases, ISSN 1080-6040, 10/2012, Volume 18, Issue 10, pp. 1625 - 1628
Echinococcus multilocularis is a zoonotic parasite in wild canids. We determined its frequency in urban coyotes (Canis latrans) in Alberta, Canada. We detected... 
ALVEOLAR ECHINOCOCCOSIS | INFECTIOUS DISEASES | LEUCKART | WOLVES | IMMUNOLOGY | HELMINTHS | Coyotes | Research | Health aspects | Risk factors | Echinococcosis | coyotes | Echinococcus multilocularis | Canada | alveolar echinococcosis | Alberta | Canis latrans
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9. Full Text TGF-β/Smad signaling pathway regulates Th17/Treg balance during Echinococcus multilocularis infection
by Pang, Nannan and Zhang, Fengbo and Ma, Xiumin and Zhu, Yuejie and Zhao, Hui and Xin, Yan and Wang, Song and Chen, Zhaolun and Wen, Hao and Ding, Jianbing
International Immunopharmacology, ISSN 1567-5769, 05/2014, Volume 20, Issue 1, pp. 248 - 257
Alveolar echinococcosis (AE) is a severe parasitic disease caused by the infection of (Em). Very little is known on the relationship between TGF-β/Smad... 
Echinococcus multilocularis | Treg/Th17 | Cytokine | TGF-β/Smad pathway | LIVER FIBROSIS | ALVEOLAR ECHINOCOCCOSIS | TREG CELLS | TGF-beta/Smad pathway | IMMUNOLOGY | RESPONSES | GROWTH-FACTOR-BETA | CD4(+) | MEDIATED SUPPRESSION | PHARMACOLOGY & PHARMACY | CYSTIC ECHINOCOCCOSIS | EXPRESSION | CD4(+)CD25(+) T-CELLS | Transforming Growth Factor beta - immunology | Liver - pathology | Receptors, Transforming Growth Factor beta - immunology | Smad Proteins - immunology | Signal Transduction | Interleukin-17 - immunology | Echinococcosis - immunology | Smad Proteins - genetics | Forkhead Transcription Factors - genetics | RNA, Messenger - metabolism | Echinococcosis - pathology | Liver - immunology | Animals | Transforming Growth Factor beta - genetics | Liver - drug effects | Female | T-Lymphocytes - immunology | Mice, Inbred BALB C | Interleukin-10 - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Index Medicus
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10. Full Text Establishment and development of Echinococcus multilocularis metacestodes in the common vole ( Microtus arvalis ) after oral inoculation with parasite eggs
by Woolsey, Ian David|Jensen, Per Moestrup|Deplazes, Peter|Kapel, Christian Moliin Outzen
Parasitology International, ISSN 1383-5769, 2015, Volume 64, Issue 6, pp. 571 - 575
Abstract Transmission of the zoonotic tapeworm, Echinococcus multilocularis mainly occurs between the red fox ( Vulpes vulpes ) and various species of vole.... 
Infectious Disease | Gastroenterology and Hepatology | Echinococcus multilocularis | Microtus arvalis | Protoscolices | POPULATION | FOXES | C57BL/6J MICE | HAIR | SECONDARY ALVEOLAR ECHINOCOCCOSIS | FIBROBLASTS | GLUCOCORTICOIDS INHIBIT | DYNAMICS | INFECTION | PARASITOLOGY | CORTISOL | Echinococcus multilocularis - growth & development | Animals | Mice, Inbred C57BL | Female | Male | Arvicolinae - parasitology | Corticosterone - metabolism | Mice | Echinococcosis - parasitology | Echinococcosis - pathology | Echinococcosis - transmission | Corticosterone | Analysis | Corticosteroids | Index Medicus
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11. Full Text First detection of Echinococcus multilocularis in Croatia
by Beck, Relja and Mihaljević, Željko and Brezak, Renata and Bosnić, Sanja and Janković, Ivana Lohman and Deplazes, Peter
Parasitology Research, ISSN 0932-0113, 2/2018, Volume 117, Issue 2, pp. 617 - 621
Echinococcus multilocularis has been spreading through Europe but has not yet been reported in Croatia. We report the results of a surveillance programme to... 
Medical Microbiology | Echinococcus multilocularis | Red foxes ( Vulpes vulpes ) | Molecular survey | Biomedicine | Immunology | Microbiology | Croatia | Red foxes (Vulpes vulpes) | ALVEOLAR | EUROPE | FOXES | VULPES-VULPES | MITOCHONDRIAL-DNA | PARASITOLOGY | Cestoda | Diphyllobothrium | Natural history | Mitochondria | Foxes | Parasites | rRNA 12S | Index Medicus
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12. Full Text Echinococcus multilocularis in a wild free-living eastern chipmunk (Tamias striatus) in Southern Ontario: A case report and subsequent field study of wild small mammals
by French, Shannon K and Jajou, Sarah and Campbell, G. Douglas and Cai, Hugh Y and Kotwa, Jonathon D and Peregrine, Andrew S and Jardine, Claire M
Veterinary Parasitology: Regional Studies and Reports, ISSN 2405-9390, 08/2018, Volume 13, pp. 234 - 237
Southern Ontario has recently been identified as a risk area for based on surveys of foxes ( ) and coyotes ( ) which act as definitive hosts of the parasite.... 
Eastern chipmunk | Echinococcus multilocularis | Intermediate host | Ontario
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13. Full Text Control strategy for Echinococcus multilocularis
by Hegglin, Daniel and Deplazes, Peter
Emerging Infectious Diseases, ISSN 1080-6040, 10/2008, Volume 14, Issue 10, pp. 1626 - 1628
Echinococcus multilocularis, the causative agent of zoonotic alveolar echinococcosis, can be controlled effectively by the experimental delivery of... 
INFECTIOUS DISEASES | FOXES | TRANSMISSION | GERMANY | TARGETING SOURCES | TAPEWORM | JAPAN | ALVEOLAR ECHINOCOCCOSIS | DYNAMICS | BAITS | VULPES-VULPES | IMMUNOLOGY | Antigens, Helminth - analysis | Echinococcus multilocularis - isolation & purification | Humans | Echinococcosis, Hepatic - prevention & control | Foxes - parasitology | Switzerland | Zoonoses - transmission | Animals | Feces - parasitology | Ecosystem | Echinococcosis, Hepatic - transmission | Echinococcus multilocularis - immunology | Disease Vectors | Praziquantel - administration & dosage | Anthelmintics - administration & dosage | Prevention | Control | Anthelmintics | Dosage and administration | Research | Parasites | Health aspects | Risk factors | Echinococcosis | Index Medicus | Echinococcus multilocularis | praziquantel | Dispatch | urbanization | vulpes | dispatch
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14. Full Text Noninvasive detection of echinococcus multilocularis tapeworm in Urban Area, Estonia
by Laurimaa, Leidi and Davison, John and Plumer, Liivi and Süld, Karmen and Oja, Ragne and Moks, Epp and Keis, Marju and Hindrikson, Maris and Kinkar, Liina and Laurimäe, Teivi and Abner, Jaana and Remm, Jaanus and Anijalg, Peeter and Saarma, Urmas
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 1, pp. 163 - 164
INFECTIOUS DISEASES | MULTIPLEX PCR | IMMUNOLOGY | GRANULOSUS | Echinococcus multilocularis - isolation & purification | Molecular Diagnostic Techniques | Animals | Echinococcosis - veterinary | Feces - parasitology | Echinococcosis - parasitology | Foxes - parasitology | Echinococcus multilocularis - genetics | Estonia | Diagnosis | Diagnosis, Noninvasive | Methods | Echinococcosis | Index Medicus | echinococcosis | zoonoses | alveolar echinococcosis | Letter | fox tapeworm | Echinococcus multilocularis | red fox | Noninvasive Detection of | noninvasive molecular diagnostics | Letters to the Editor | feces | Tapeworm in Urban Area, Estonia
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15. Full Text Echinococcus multilocularis and Trichinella spiralis in golden jackals (Canis aureus) of Hungary
by Széll, Z and Marucci, G and Pozio, E and Sréter, T
Veterinary Parasitology, ISSN 0304-4017, 10/2013, Volume 197, Issue 1-2, pp. 393 - 396
Over the last decades the distribution area of the golden jackal ( ) has increased significantly in Europe, particularly in the Balkan Peninsula and in Central... 
Echinococcus multilocularis | Golden jackal | Trichinella spiralis | Canis aureus | Hungary | Europe | PIGS | TRICHINOSIS | HOST | FOXES VULPES-VULPES | BRITOVI | VETERINARY SCIENCES | PSEUDOSPIRALIS | SPATIAL-DISTRIBUTION | EPIDEMIOLOGY | PCR | PARASITOLOGY | Echinococcus multilocularis - isolation & purification | Jackals | Trichinellosis - veterinary | Animals | Echinococcosis - veterinary | Echinococcosis - epidemiology | Hungary - epidemiology | Trichinellosis - epidemiology | Trichinella spiralis - isolation & purification | Zoonoses | Index Medicus
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16. Full Text Echinococcus multilocularis and Echinococcus canadensis in wolves from western Canada
by Schurer, Janna M and Gesy, Karen M and Elkin, Brett T and Jenkins, Emily J
Parasitology, ISSN 0031-1820, 02/2014, Volume 141, Issue 2, pp. 159 - 163
Echinococcus species are important parasites of wildlife, domestic animals and people worldwide; however, little is known about the prevalence, intensity and... 
geographic distribution | Canada | wolf | Echinococcus granulosus | genotype | CANIS-LUPUS L | HELMINTHS | CHINA | ALASKA | GENUS ECHINOCOCCUS | GRANULOSUS | INFECTION | CYSTIC ECHINOCOCCOSIS | STRAIN | PARASITOLOGY | NORTH-AMERICA | Geography | Echinococcus multilocularis - isolation & purification | Coinfection | Prevalence | Echinococcosis - veterinary | Manitoba - epidemiology | Saskatchewan - epidemiology | Echinococcosis - epidemiology | Echinococcus - genetics | Molecular Sequence Data | Genotype | Echinococcus - isolation & purification | Genetic Variation | Animals | Base Sequence | Sequence Analysis, DNA - veterinary | Echinococcosis - parasitology | Wolves - parasitology | Echinococcus multilocularis - genetics | Northwest Territories - epidemiology | Index Medicus
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17. Full Text Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice
by Wang, Junhua and Vuitton, Dominique A and Müller, Norbert and Hemphill, Andrew and Spiliotis, Markus and Blagosklonov, Oleg and Grandgirard, Denis and Leib, Stephen L and Shalev, Itay and Levy, Gary and Lu, Xiaomei and Lin, Renyong and Wen, Hao and Gottstein, Bruno
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 05/2015, Volume 9, Issue 5, pp. e0003755 - e0003755
Background The growth potential of the tumor-like Echinococcus multilocularis metacestode (causing alveolar echinococcosis, AE) is directly linked to the... 
IMMUNE-RESPONSE | ALLOGRAFT-REJECTION | TGF-BETA | CYTOKINE PRODUCTION | PROTHROMBINASE | ALVEOLAR ECHINOCOCCOSIS | PERIPARASITIC GRANULOMA | MONONUCLEAR-CELLS | CONTRIBUTES | T-CELLS | PARASITOLOGY | TROPICAL MEDICINE | Dendritic Cells - immunology | CD4 Antigens | Th2 Cells - immunology | Interleukin-17 - biosynthesis | Th1 Cells - immunology | Fibrinogen - genetics | T-Lymphocytes, Regulatory - immunology | Echinococcosis, Hepatic - immunology | Animals | Flow Cytometry | Echinococcosis, Hepatic - parasitology | Echinococcus multilocularis - immunology | Th17 Cells - immunology | Dendritic Cells - cytology | Mice | Fibrinogen - immunology | Concanavalin A - immunology | Echinococcosis | Index Medicus | Spleen | Flow cytometry | Cytokines | Infections | Parasites | Gene expression | Experiments | Studies | Proteins | Cell growth | Lymphocytes | Parasitic diseases | Rodents | Deaths | Chronic illnesses
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