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European Journal of Immunology, ISSN 0014-2980, 2019, Volume 49, Issue 4, pp. 600 - 610
Efferocytosis is essential for homeostasis and prevention of the inflammatory and autoimmune diseases resulting from apoptotic cell lysis. CD93 is a... 
Efferocytosis | CD93 | Opsonin | Phagocytosis | Integrins
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2/2017, Volume 37, Issue 2, pp. 183 - 189
Atherosclerosis is initiated by the subendothelial accumulation of apolipoprotein B-containing lipoproteins (apoB LPs), which initiates a sterile inflammatory... 
atherosclerosis | macrophages | necrosis | inflammation resolution | efferocytosis
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12859 - 12859
Chronic unresolved inflammation plays a causal role in the development of advanced atherosclerosis, but the mechanisms that prevent resolution in... 
NUCLEAR-LOCALIZATION | LIPOXIN A | A HYDROLASE | OXIDATIVE STRESS | ANTIINFLAMMATORY ACTIVITY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | RESOLUTION | EFFEROCYTOSIS | 5-LIPOXYGENASE | HUMAN PHAGOCYTES
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2011, Volume 2, pp. 57 - 57
A critical function of macrophages within the inflammatory milieu is the removal of dying cells by a specialized phagocytic process called efferocytosis ("to... 
Efferocytosis | Inflammation | Alternative activation | Apoptotic cell | Classical activation | Macrophage | macrophage | apoptotic cell | classical activation
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 10/2019, Volume 1866, Issue 10, pp. 1595 - 1607
The rapid and precise clearance of apoptotic cells (efferocytosis) involves a series of phagocytic processes through which apoptotic cells are recognized,... 
Efferocytosis | Phosphatidylinositol-4,5-bisphosphate | ArhGAP12 | Rac1 activity | Phagosome maturation | Index Medicus
Journal Article
Journal of Immunological Methods, ISSN 0022-1759, 10/2019, Volume 473, pp. 112636 - 112636
Macrophages are a diverse population of cells originating from the myeloid lineage, which form an important component of the innate immune system, helping to... 
Efferocytosis | CD14 | MerTK | High content imaging | Multiparametric | Macrophage | Index Medicus
Journal Article
European Journal of Immunology, ISSN 0014-2980, 9/2011, Volume 41, Issue 9, pp. 2515 - 2518
Accumulating evidence supports the notion that defective phagocytic clearance of dying cells, or defective “efferocytosis,” is causally linked to the... 
Efferocytosis | Macrophage
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2018, Volume 115, Issue 36, pp. E8469 - E8478
Inflammatory responses are terminated by the clearance of dead cells, a process termed efferocytosis. A consequence of efferocytosis is the synthesis of the... 
DC EFFEROCYTOSIS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | efferocytosis | EP4 | INNATE | prostaglandin E-2 | CYCLIC-AMP | IL-17-PRODUCING T-CELLS | STAPHYLOCOCCUS-AUREUS | DIFFERENTIATION | infected apoptotic cells | CITROBACTER-RODENTIUM | Th17 cells | CROSS-PRESENTATION
Journal Article
Virology, ISSN 0042-6822, 02/2018, Volume 515, pp. 176 - 190
Efferocytosis, the phagocytic clearance of apoptotic cells, can provide host protection against certain types of viruses by mediating phagocytic clearance of... 
HIV-1 | Efferocytosis | Protein S | Mer | Gas6 | Phosphatidylserine | Phagocytosis | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Many studies have noted similarities between atherosclerosis and cancer including pronounced cellular plasticity, clonal expansion of cellular subtypes,... 
atherosclerosis | macrophages | efferocytosis | smooth muscle | oncogenes | neoplasms | myocytes
Journal Article
Circulation Journal, ISSN 1346-9843, 2016
Macrophage apoptosis and the ability of macrophages to clean up dead cells, a process called efferocytosis, are crucial determinants of atherosclerosis lesion... 
SR-BI | Atherosclerosis | Efferocytosis | Macrophages | Apoptosis
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2669 - 2683
Tyro3, Axl, and Mertk (TAM) represent a family of homologous tyrosine kinase receptors known for their functional role in phosphatidylserine (PS)-dependent... 
MERTK INHIBITION | SIGNALING PATHWAYS | ONCOLOGY | GROWTH | EFFEROCYTOSIS | PROTEIN-S | PHOSPHATIDYLSERINE | EXPRESSION | SMALL-MOLECULE INHIBITION | AXL KINASE | FAMILY
Journal Article
Cancer Research, ISSN 0008-5472, 10/2018, Volume 78, Issue 19, pp. 5600 - 5617
Tumor-associated macrophages (TAM) are causally associated with tumorigenesis as well as regulation of antitumor immune responses and have emerged as potential... 
PHAGOSOME MATURATION | MATRIX METALLOPROTEINASES | CLEARANCE | PHAGOCYTOSIS | DENDRITIC CELLS | ANGIOGENESIS | ONCOLOGY | APOPTOTIC CELLS | PANCREATIC-CANCER | EFFEROCYTOSIS | PROGRESSION
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 10/2018, Volume 9
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 12/2017, Volume 27, Issue 17, pp. 1412 - 1431
Aims: 15-Deoxy-Δ 12,14 -prostaglandin J 2 (15d-PGJ 2 ) has been shown to rescue cells from inflammatory insults and to participate in the resolution of acute... 
Original Research Communications | prostaglandin J | 15-Deoxy-Δ | heme oxygenase-1 | Nrf2 | resolution of inflammation | efferocytosis | Index Medicus
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3, pp. 4 - 4
Monocytes that migrate into tissues during inflammatory episodes and differentiate to macrophages were previously classified as classically (M1) or... 
Efferocytosis | Pro-resolving lipid mediators | Macrophage differentiation | Resolution of inflammation | IMMUNOLOGY | macrophage differentiation | pro-resolving lipid mediators | resolution of inflammation | efferocytosis
Journal Article
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