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1. Full Text Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II
by Jones, Courtney L and Stevens, Brett M and D'Alessandro, Angelo and Culp-Hill, Rachel and Reisz, Julie A and Pei, Shanshan and Gustafson, Annika and Khan, Nabilah and DeGregori, James and Pollyea, Daniel A and Jordan, Craig T
Blood, ISSN 0006-4971, 07/2019, Volume 134, Issue 4, pp. 389 - 394
Life Sciences & Biomedicine | Hematology | Science & Technology | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Glutathione - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Oxidative Phosphorylation | Electron Transport Complex II - antagonists & inhibitors | Energy Metabolism | Neoplastic Stem Cells - metabolism | Adenosine Triphosphate - metabolism | Biomarkers | Succinate Dehydrogenase - metabolism | Cysteine - metabolism | Index Medicus | Abridged Index Medicus | 33 | Brief Report | Myeloid Neoplasia | 6
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2. Full Text Inhibition of mitochondrial complex II by the anticancer agent lonidamine
by Guo, Lili and Shestov, Alexander A and Worth, Andrew J and Nath, Kavindra and Nelson, David S and Leeper, Dennis B and Glickson, Jerry D and Blair, Ian A
The Journal of biological chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 1, pp. 42 - 57
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Pentose Phosphate Pathway - drug effects | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Humans | Glutamine - metabolism | Electron Transport Complex II - antagonists & inhibitors | Metabolic Flux Analysis | Malates - metabolism | Oxidation-Reduction - drug effects | Antineoplastic Agents - pharmacology | Cell Death - drug effects | NADP - metabolism | Diacetyl - analogs & derivatives | Melanoma - metabolism | Diacetyl - pharmacology | Citric Acid Cycle - drug effects | Mitochondria - metabolism | Melanoma - pathology | Mitochondria - drug effects | Naphthalenes - pharmacology | Indazoles - pharmacology | Electron Transport Complex II - metabolism | Models, Biological | Succinic Acid - metabolism | Cell Line, Tumor | Fumarates - metabolism | Index Medicus | cancer therapy | anticancer drug | drug action | chromatography | glycolysis | Metabolism | glutamine | glucose metabolism | high-performance liquid chromatography (HPLC) | glutamate | mass spectrometry (MS)
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3. Full Text Clade II nitrous oxide respiration of Wolinella succinogenes depends on the NosG, ‐C1, ‐C2, ‐H electron transport module, NosB and a Rieske/cytochrome bc complex
by Hein, Sascha and Witt, Samantha and Simon, Jörg
Environmental microbiology, ISSN 1462-2912, 12/2017, Volume 19, Issue 12, pp. 4913 - 4925
Life Sciences & Biomedicine | Microbiology | Science & Technology | Multigene Family - genetics | Electron Transport Complex III - genetics | Oxidation-Reduction | Oxidoreductases - genetics | Electron Transport - genetics | Cytoplasm - metabolism | Cytochromes c - genetics | Wolinella - genetics | Nitrous Oxide - metabolism | Wolinella - metabolism | Nitrates - metabolism | Cytochromes b - genetics | Wolinella - enzymology | Fumarates - metabolism | Electron Transport - physiology | Cytochrome c | Sulfur compounds | Analysis | Nitrification | Nitrous oxide | Iron proteins | Electron transport | Cytochrome | Iron-sulfur proteins | Reductases | Iron | Gene deletion | Sulphur | Deletion mutant | Proteins | Electron transport chain | Microorganisms | Reduction | Clonal deletion | Nitrous oxides | Oxidation | Sulfur | Gene clusters | Sulfur proteins | Cells | Nitric-oxide synthase | Mutants | Biogeochemistry | Nitrogen cycle | Cytochromes | Yield | Respiration | Enzymology | Transport | Reductase | Electrons | Index Medicus
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4. Full Text Reactive oxygen species are generated by the respiratory complex II – evidence for lack of contribution of the reverse electron flow in complex I
by Moreno‐Sánchez, Rafael and Hernández‐Esquivel, Luz and Rivero‐Segura, Nadia A and Marín‐Hernández, Alvaro and Neuzil, Jiri and Ralph, Stephen J and Rodríguez‐Enríquez, Sara
The FEBS journal, ISSN 1742-464X, 02/2013, Volume 280, Issue 3, pp. 927 - 938
reverse electron flow | anti‐cancer drugs | mitochondria | respiratory complex II | ROS | respiratory complex II | anti-cancer drugs | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Electron Transport - drug effects | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Glutamic Acid - pharmacology | Malates - pharmacology | Mitochondria, Liver - metabolism | Polyenes - pharmacology | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria, Heart - drug effects | Electron Transport Complex I - metabolism | Hydrogen Peroxide - metabolism | Mitochondria, Liver - drug effects | Animals | Thenoyltrifluoroacetone - pharmacology | Succinic Acid - pharmacology | Cattle | Electron Transport Complex II - metabolism | Rotenone - pharmacology | Cell Line, Tumor | Analysis | Mitochondrial DNA | Cytochrome b | Thermodynamics | Mitochondria | Oxygen | Molecular biology | Electrons | Index Medicus
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5. Full Text MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture
by Friedman, Jonathan R and Mourier, Arnaud and Yamada, Justin and Michael McCaffery, J and Nunnari, Jodi
eLife, ISSN 2050-084X, 04/2015, Volume 2015, Issue 4, pp. 1 - 61
Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Saccharomyces cerevisiae - genetics | Mitochondrial Proteins - genetics | Saccharomyces cerevisiae - ultrastructure | Electron Transport Complex I - metabolism | Mitochondria - ultrastructure | Saccharomyces cerevisiae - metabolism | Mitochondria - genetics | Electron Transport Complex I - genetics | Mitochondrial Proteins - metabolism | Recombination, Genetic | Membrane Proteins - metabolism | Electron Transport Complex II - chemistry | Recombinant Proteins - metabolism | Electron Transport Complex II - genetics | Membrane Proteins - genetics | Recombinant Proteins - chemistry | Cardiolipins - metabolism | Mitochondria - metabolism | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Cardiolipins - chemistry | Mitochondrial Membranes - metabolism | Electron Transport Complex I - chemistry | Membrane Proteins - chemistry | Electron Transport Complex II - metabolism | Mitochondrial Membranes - ultrastructure | Mitochondrial Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae Proteins - chemistry | Cytochrome | Membranes | Membrane structure | Copy number | Cloning | Lipids | Proteins | Mitochondria | Functional morphology | Dimensional analysis | Cristae | Cardiolipin | Infrared imaging systems | Apoptosis | Index Medicus
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6. Full Text Q-site inhibitor induced ROS production of mitochondrial complex II is attenuated by TCA cycle dicarboxylates
by Siebels, Ilka and Dröse, Stefan
Biochimica et biophysica acta. Bioenergetics, ISSN 0005-2728, 10/2013, Volume 1827, Issue 10, pp. 1156 - 1164
Complex II | Dicarboxylates | Atpenin A5 | Mitochondria | Succinate:ubiquinone oxidoreductase | Reactive oxygen species (ROS) | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Dicarboxylic Acids - metabolism | Electron Transport - drug effects | Electron Transport Complex I - antagonists & inhibitors | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Citric Acid Cycle - drug effects | Ubiquinone - metabolism | Mitochondria, Heart - drug effects | Electron Transport Complex I - metabolism | Hydrogen Peroxide - metabolism | Animals | Cattle | Electron Transport Complex II - metabolism | Succinic Acid - metabolism | Superoxides - metabolism | Electron Transport Complex II - drug effects | Binding Sites | Pyridones - pharmacology | Superoxide | Mitochondrial DNA
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7. Full Text ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use
by Acín-Pérez, Rebeca and Carrascoso, Isabel and Baixauli, Francesc and Roche-Molina, Marta and Latorre-Pellicer, Ana and Fernández-Silva, Patricio and Mittelbrunn, María and Sanchez-Madrid, Francisco and Pérez-Martos, Acisclo and Lowell, Clifford A and Manfredi, Giovanni and Enríquez, José Antonio
Cell metabolism, ISSN 1550-4131, 06/2014, Volume 19, Issue 6, pp. 1020 - 1033
Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins - metabolism | Cell Hypoxia - physiology | Phosphorylation | Cells, Cultured | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Hydrogen Peroxide - metabolism | Mice, Knockout | Starvation - metabolism | Flavin-Adenine Dinucleotide - metabolism | Lymphocyte Activation - immunology | Animals | Electron Transport Complex II - metabolism | src-Family Kinases - metabolism | Succinate Dehydrogenase - metabolism | Mice | Mice, Inbred BALB C | Electron Transport - physiology | src-Family Kinases - genetics | NAD - metabolism | Mitochondrial DNA | Hydrogen peroxide | Energy use | T cells | Index Medicus
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8. Full Text 'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich's ataxia'
by Abeti, R and Parkinson, M.H and Hargreaves, I.P and Angelova, P.R and Sandi, C and Pook, M.A and Giunti, P and Abramov, A.Y
Cell death & disease, ISSN 2041-4889, 05/2016, Volume 7, Issue 5, pp. e2237 - e2237
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neurons - pathology | Electron Transport Complex III - genetics | Electron Transport Complex III - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Friedreich Ataxia - pathology | Glutathione - metabolism | Humans | Electron Transport Complex I - metabolism | Iron-Binding Proteins - metabolism | Friedreich Ataxia - genetics | Electron Transport Complex I - genetics | Membrane Potential, Mitochondrial | Neurons - metabolism | Disease Models, Animal | Friedreich Ataxia - metabolism | Electron Transport Complex II - genetics | Signal Transduction | Cerebellum - metabolism | Gene Expression Regulation | Mitochondria - metabolism | Mitochondria - pathology | Iron - metabolism | Cerebellum - pathology | Animals | Electron Transport Complex II - metabolism | Iron-Binding Proteins - genetics | Mice | Lipid Peroxidation - genetics | Mutation | Primary Cell Culture | Index Medicus | Original
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