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ellipticines - pharmacology (74) 74
ellipticines - chemical synthesis (67) 67
chemistry (62) 62
science & technology (62) 62
humans (61) 61
animals (57) 57
life sciences & biomedicine (50) 50
antineoplastic agents - chemical synthesis (47) 47
ellipticines - chemistry (47) 47
ellipticine (46) 46
antineoplastic agents - pharmacology (44) 44
mice (42) 42
biological and medical sciences (39) 39
structure-activity relationship (36) 36
organic chemistry (35) 35
medical sciences (34) 34
antineoplastic agents (32) 32
cell line, tumor (31) 31
pharmacology. drug treatments (30) 30
antineoplastic agents - chemistry (28) 28
molecular structure (26) 26
biochemistry & molecular biology (25) 25
exact sciences and technology (25) 25
physical sciences (25) 25
alkaloids - chemical synthesis (24) 24
pharmacology & pharmacy (24) 24
preparations and properties (23) 23
heterocyclic compounds (22) 22
drug screening assays, antitumor (20) 20
general aspects (20) 20
heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings (20) 20
cell survival - drug effects (19) 19
carbazoles - chemical synthesis (18) 18
cytotoxicity (18) 18
cell proliferation - drug effects (15) 15
chemistry, multidisciplinary (14) 14
leukemia l1210 - drug therapy (14) 14
tumor cells, cultured (14) 14
alkaloids (13) 13
carbazoles - pharmacology (13) 13
chemical phenomena (13) 13
chemistry, medicinal (13) 13
synthesis (13) 13
cancer (12) 12
dna - metabolism (12) 12
ellipticines - metabolism (12) 12
ellipticines - therapeutic use (12) 12
magnetic resonance spectroscopy (12) 12
male (12) 12
oncology (12) 12
rats (12) 12
dose-response relationship, drug (11) 11
female (11) 11
research (11) 11
carbazoles - chemistry (10) 10
chemistry, organic (10) 10
olivacine (10) 10
topoisomerase ii inhibitors (10) 10
alkaloids - pharmacology (9) 9
analysis (9) 9
dna (9) 9
antineoplastic agents, phytogenic - pharmacology (8) 8
cell cycle - drug effects (8) 8
cell line (8) 8
chemotherapy (8) 8
cyclization (8) 8
ellipticines (8) 8
intercalating agents - pharmacology (8) 8
kinetics (8) 8
lung neoplasms - drug therapy (8) 8
models, molecular (8) 8
carbazole (7) 7
dna damage (7) 7
dna topoisomerases, type ii - metabolism (7) 7
drug design (7) 7
indicators and reagents (7) 7
antineoplastic agents - toxicity (6) 6
apoptosis (6) 6
apoptosis - drug effects (6) 6
carbazoles (6) 6
cell cycle (6) 6
cell division - drug effects (6) 6
chemical properties (6) 6
deoxyribonucleic acid--dna (6) 6
drug evaluation, preclinical (6) 6
ellipticines - administration & dosage (6) 6
ellipticines - pharmacokinetics (6) 6
ellipticines - toxicity (6) 6
enzyme inhibitors - pharmacology (6) 6
general pharmacology (6) 6
in vitro techniques (6) 6
intercalating agents - chemical synthesis (6) 6
leukemia p388 - drug therapy (6) 6
nanoparticles (6) 6
neoplasms, experimental - drug therapy (6) 6
pyridocarbazole (6) 6
tumors (6) 6
alkaloids - chemistry (5) 5
antineoplastic agents - administration & dosage (5) 5
antineoplastic agents - metabolism (5) 5
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1. Full Text Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
by Schmidt, Arndt W and Reddy, Kethiri R and Knölker, Hans-Joachim
Chemical reviews, ISSN 0009-2665, 06/2012, Volume 112, Issue 6, pp. 3193 - 3328
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Carbazoles - chemistry | Alkaloids - pharmacology | Quinones - chemical synthesis | Alkaloids - isolation & purification | Organic Chemistry Phenomena | Alkaloids - chemical synthesis | Carbazoles - chemical synthesis | Pyrroles - chemical synthesis | Indole Alkaloids - chemical synthesis | Ellipticines - chemical synthesis | Benzoquinones - chemical synthesis | Molecular Structure | Furans - chemical synthesis | Carbazoles - pharmacology | Alkaloids - chemistry | Palladium catalysts | Alkaloids | Usage | Analysis | Heterocyclic aromatic compounds | Chemical bonds | Chemical properties | Ring formation (Chemistry) | Evolutionary biology | Chemical synthesis | Organic chemistry | Index Medicus
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2. Full Text Total Synthesis of Ellipticine Quinones, Olivacine, and Calothrixin B
by Ramkumar, Nagarajan and Nagarajan, Rajagopal
Journal of organic chemistry, ISSN 0022-3263, 01/2014, Volume 79, Issue 2, pp. 736 - 741
Quinones - chemistry | Indole Alkaloids - chemical synthesis | Ellipticines - chemical synthesis | Quinones - chemical synthesis | Molecular Structure | Indole Alkaloids - chemistry | Ellipticines - chemistry | Antimalarials | Research | Chemical properties | Chemical synthesis | Index Medicus
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3. Full Text Benzannulation of Indoles to Carbazoles and Its Applications for Syntheses of Carbazole Alkaloids
by Zheng, Xiaojian and Lv, Leiyang and Lu, Shenglin and Wang, Wenxiao and Li, Zhiping
Organic letters, ISSN 1523-7060, 10/2014, Volume 16, Issue 19, pp. 5156 - 5159
Carbazoles - chemistry | Ellipticines - chemical synthesis | Stereoisomerism | Alkaloids - chemical synthesis | Carbazoles - chemical synthesis | Molecular Structure | Ellipticines - chemistry | Indoles - chemistry | Alkaloids - chemistry | Index Medicus
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4. Full Text Synthesis and in vitro antitumor activity of novel 2-alkyl-5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium and 2-alkylellipticin-2-ium chloride derivatives
by Mori, Ryota and Kato, Asako and Komenoi, Kousuke and Kurasaki, Haruaki and Iijima, Touru and Kawagoshi, Masashi and Kiran, Y.B and Takeda, Sho and Sakai, Norio and Konakahara, Takeo
European journal of medicinal chemistry, ISSN 0223-5234, 07/2014, Volume 82, pp. 16 - 35
Nitrosourea | Ellipticine | Synthesis | SAR | Antitumor activity | Cytotoxicity | HeLa S-3 | 6H-pyrido[4,3-b]carbazole | Cell Survival - drug effects | Carbazoles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Ellipticines - pharmacology | Carbazoles - chemical synthesis | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Dose-Response Relationship, Drug | Ellipticines - chemical synthesis | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | HeLa Cells | Tumor Cells, Cultured | Carbazoles - pharmacology | Ellipticines - chemistry | Drug Screening Assays, Antitumor | Index Medicus
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5. Full Text Synthesis of Ellipticine:  A Radical Cascade Protocol to Aryl- and Heteroaryl-Annulated[b]carbazoles
by Pedersen, Jan M and Bowman, W. Russell and Elsegood, Mark R. J and Fletcher, Anthony J and Lovell, Peter J
Journal of organic chemistry, ISSN 0022-3263, 12/2005, Volume 70, Issue 25, pp. 10615 - 10618
Organic chemistry | Chemistry | Heterocyclic compounds | Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings | Preparations and properties | Exact sciences and technology | Ellipticines - chemical synthesis | Carbazoles | Antineoplastic Agents - chemical synthesis | Alkaloids | Amides | Chemical properties | Research | Radicals (Chemistry) | Index Medicus
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6. Full Text Recent synthesis of ellipticine and its derivatives
by Ibrahim-Ouali, Malika and Dumur, Frederic
ARKIVOC free online journal of organic chemistry, ISSN 1551-7012, 04/2018, Volume 2018, Issue 1, pp. 216 - 243
Medicinal Chemistry | Organic chemistry | Chemical Sciences
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7. Full Text Multigram scale synthesis of polycyclic lactones and evaluation of antitumor and other biological properties
by Grau, Laura and Romero, Manel and Privat-Contreras, Cristian and Presa, Daniela and Viñas, Miquel and Morral, Jordi and Pors, Klaus and Rubio-Martinez, Jaime and Pujol, Maria Dolors
European journal of medicinal chemistry, ISSN 0223-5234, 01/2020, Volume 185, pp. 111807 - 111807
Ellipticine | Antitumor compounds | Tetracyclic lactones | 1,4-Benzodioxine derivatives | Polycyclic Compounds - chemistry | Polycyclic Compounds - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Models, Molecular | tau Proteins - metabolism | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Cytochrome P-450 CYP1A1 - metabolism | Lactones - pharmacology | Dose-Response Relationship, Drug | Polycyclic Compounds - pharmacology | Lactones - chemical synthesis | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Tumor Cells, Cultured | Cell Cycle - drug effects | tau Proteins - antagonists & inhibitors | Lactones - chemistry | Index Medicus
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8. Full Text Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines
by Willemann, C and Grünert, R and Bednarski, P.J and Troschütz, R
Bioorganic & medicinal chemistry, ISSN 0968-0896, 07/2009, Volume 17, Issue 13, pp. 4406 - 4419
Cytotoxicity | Carbolines | Heterocyclic compounds | Pyridinediamines | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Pyridines - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Pyridines - chemical synthesis | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Antineoplastic Agents - toxicity | Ellipticines - toxicity | Neoplasms - drug therapy | Pyridines - toxicity | Cell Line, Tumor | Diamines - chemistry | Diamines - toxicity | Cell Proliferation - drug effects | Diamines - chemical synthesis | Drug Screening Assays, Antitumor | Alkaloids | Pyridine | Index Medicus
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9. Full Text Synthesis and activity against mycobacterium tuberculosis of olivacine and oxygenated derivatives
by Schmidt, Ulrike and Theumer, Gabriele and Jäger, Anne and Kataeva, Olga and Wan, Baojie and Franzblau, Scott G and Knölker, Hans-Joachim
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 6, p. 1402
Cyclization | Olivacine | Pyrido | Palladium | 3-b]carbazoles | Catalysis | Inhibitory activity | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Carbazoles | Tuberculosis | Derivatives | Oxygenation | Chemical synthesis | Carbazole | Index Medicus | catalysis | palladium | inhibitory activity | pyrido[4,3-b]carbazoles | cyclization | olivacine
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10. Full Text Synthesis and anti-proliferative activity of novel azazerumbone conjugates with chalcones
by Truong, Vuong Van and Nam, Tran Duy and Hung, Truong Ngoc and Nga, Nguyen Thi and Quan, Pham Minh and Chinh, Luu Van and Jung, Sang-Hun
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 11/2015, Volume 25, Issue 22, pp. 5182 - 5185
Azazerumbone | Zerumbone | Conjugate | Anti-proliferative activity | Chalcone | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Ellipticines - pharmacology | Lactams - chemical synthesis | Structure-Activity Relationship | Chalcones - chemical synthesis | Chalcones - pharmacology | Lactams - pharmacology | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Sesquiterpenes - pharmacology | Drug Screening Assays, Antitumor | Index Medicus
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11. Full Text Concise synthesis and antiproliferative activity evaluation of ellipticine quinone and its analogs
by Nishiyama, Takashi and Hatae, Noriyuki and Mizutani, Masataka and Yoshimura, Teruki and Kitamura, Tsuyoshi and Miyano, Mana and Fujii, Mami and Satsuki, Nanase and Ishikura, Minoru and Hibino, Satoshi and Choshi, Tominari
European journal of medicinal chemistry, ISSN 0223-5234, 08/2017, Volume 136, pp. 1 - 13
Ring-Closing Metathesis | Pyrido[4,3-b]carbozole-5,11-quinone | Carbazole-1,4-quinone | Antiproliferative activity | Ellipticine quinone | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Ellipticines - pharmacology | Benzoquinones - chemistry | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Benzoquinones - pharmacology | Dose-Response Relationship, Drug | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Tumor Cells, Cultured | Ellipticines - chemistry | Drug Screening Assays, Antitumor | Drugstores | Dehydrogenation | Quinone | Analysis | Pharmacy | Synthesis | Organic compounds | Index Medicus
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