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Statistics in Medicine, ISSN 0277-6715, 07/2019, Volume 38, Issue 17, pp. 3123 - 3138
Journal Article
Saudi Pharmaceutical Journal, ISSN 1319-0164, 02/2017, Volume 25, Issue 2, pp. 165 - 175
The study of the magnitude and variation of drug response is defined as pharmacodynamics (PDs). PD models examine plasma concentration and effect relationship.... 
Ligand binding | Pharmacodynamics | Emax model | Receptor | Competitive binding | Pharmacodynamic model | Fractional occupancy
Journal Article
BMC cancer, ISSN 1471-2407, 10/2017, Volume 17, Issue 1, pp. 698 - 698
Background: Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as... 
NIH LINCS program | Web interface | Data analysis | Bioconductor | GR metrics | GRmax | GR50 | IC50 | Dose response | Shiny | Emax | R package | METRICS | SENSITIVITY | GR(max) | ONCOLOGY | CANCER DRUGS | E-max | Dose-Response Relationship, Drug | Cell Line | Reproducibility of Results | Animals | Humans | Software | Data Mining - methods | Index Medicus
Journal Article
BMC cancer, 10/2017, Volume 17, Issue 1, p. 698
Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a... 
Dose-Response Relationship, Drug | Cell Line | Reproducibility of Results | Animals | Humans | Software | Data Mining - methods
Journal Article
Journal of neurosurgery, ISSN 0022-3085, 02/2016, Volume 124, Issue 2, pp. 411 - 416
Journal Article
Journal of the American Statistical Association, ISSN 0162-1459, 09/2012, Volume 107, Issue 499, pp. 1140 - 1151
Journal Article
Statistics in Medicine, ISSN 0277-6715, 11/2017, Volume 36, Issue 27, pp. 4401 - 4413
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 04/2015, Volume 91, pp. 47 - 51
Journal Article
Statistics in Biopharmaceutical Research, ISSN 1946-6315, 07/2016, Volume 8, Issue 3, pp. 307 - 315
The evaluation of equivalence of response profiles including both dose-response and time-response curves plays an important role in the development of... 
Equivalence | Biosimilarity | Emax model | METAANALYSIS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DRUG DEVELOPMENT | STATISTICS & PROBABILITY
Journal Article
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, ISSN 1089-8603, 11/2014, Volume 42, pp. 131 - 132
Conference Proceeding
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2013, Volume 146, Issue 3, pp. 522 - 529
Objectives Continuous flow in the Fontan circulation results in impairment of pulmonary artery endothelial function, increased pulmonary arterial resistance,... 
Cardiothoracic Surgery | NO | SVC | eNOS | nitric oxide | pulmonary artery | 50% of the maximal response | PVP | PVR | maximal response | pulmonary vein pressure | PA | endothelial nitric oxide synthase | superior vena cava | pulmonary vascular resistance | pulmonary artery pressure | EC | Emax | PAP | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | RABBIT LUNGS | RESPIRATORY SYSTEM | NITRIC-OXIDE SYNTHASE | VASCULAR-RESISTANCE | VASODILATION | RELEASE | BLOOD-FLOW | HYPERTENSION | EXPRESSION | BIDIRECTIONAL CAVOPULMONARY SHUNT | Hypertension, Pulmonary - physiopathology | Endothelium, Vascular - drug effects | Fontan Procedure - adverse effects | Pulmonary Artery - surgery | Endothelium, Vascular - surgery | Vasodilation | Dose-Response Relationship, Drug | Microcirculation | Pulmonary Artery - metabolism | Pulsatile Flow - drug effects | Time Factors | Swine | Models, Animal | Nitric Oxide Synthase Type III - metabolism | Vascular Resistance | Vasodilator Agents - pharmacology | Endothelium, Vascular - physiopathology | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Animals | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Pulmonary Circulation - drug effects | Hypertension, Pulmonary - etiology | Pulmonary Artery - pathology | Health aspects | Children | Endothelium | Index Medicus | Abridged Index Medicus
Journal Article
Annals of Statistics, ISSN 0090-5364, 10/2017, Volume 45, Issue 5, pp. 2102 - 2132
Journal Article
Statistical Methods in Medical Research, ISSN 0962-2802, 9/2018, Volume 27, Issue 9, pp. 2694 - 2721
Journal Article
Radiation Measurements, ISSN 1350-4487, 2011, Volume 46, Issue 4, pp. 413 - 417
The angular distribution of Np fission fragments was measured over the energy range 7.4 MeV–9.2 MeV in steps of 0.4 MeV of bremsstrahlung radiation. Lexan... 
Bremsstrahlung: 237Np (γ, F) | Solid state nuclear track detector | Photon difference method | Fission | Emax, = 7.4 − 9.2 MeV | Fission fragment angular distributions | Bremsstrahlung | Emax, = 7.4 - 9.2 MeV | Np (γ, F) | Theorems | Accelerators | Mathematical analysis | Barriers | Fragments | Angular distribution | Photons
Journal Article
Journal of the Mechanical Behavior of Biomedical Materials, ISSN 1751-6161, 11/2018, Volume 87, pp. 197 - 204
The objective of this study was to compare the resistance to failure of three types of all-ceramic crowns under static and cyclic contact loading. Three types... 
Zirconia | Fatigue | Load capacity | Flat slice model | FEM | IPS e.max CAD | VENEERS | MATERIALS SCIENCE, BIOMATERIALS | SHEAR BOND STRENGTH | ENGINEERING, BIOMEDICAL | BEHAVIOR | RESTORATIONS | FAILURE LOAD | RESIDUAL-STRESSES | FRACTURE-RESISTANCE | IPS emax CAD | RESIN CEMENTS | DENTAL CERAMICS | Mechanical properties | Dynamic testing | Crowns (Dentistry) | Methods | Materials
Journal Article
Statistics in Biopharmaceutical Research, ISSN 1946-6315, 04/2017, Volume 9, Issue 2, pp. 137 - 146
A meta-analysis of dose-response studies is reported for small-molecule drugs approved by the U.S. Food and Drug Administration (FDA) between January 2009 and... 
Bayesian pharmacometric models | Dosing design | Emax | METAANALYSIS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | STATISTICS & PROBABILITY | OPTIMAL DESIGNS | MODEL UNCERTAINTY | STEPWISE CONFIDENCE-INTERVALS
Journal Article