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Journal of Biological Chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 52, pp. 44295 - 44305
Activation of the PI3K pathway plays a pivotal role in regulating the inflammatory response. The loss of mTORC2 has been shown to abrogate the activation of... 
RAPTOR | BINDING PARTNER | ACTIVATION | PATHWAY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPOPOLYSACCHARIDE | RICTOR | AKT | MICE | PROTEIN-KINASE B | Forkhead Transcription Factors - immunology | Inflammation - chemically induced | Dendritic Cells - immunology | Immunity, Innate - genetics | Embryo, Mammalian - metabolism | Proto-Oncogene Proteins c-akt - genetics | Signal Transduction - immunology | Inflammation - metabolism | Phosphorylation - genetics | Forkhead Transcription Factors - metabolism | Trans-Activators - genetics | Phosphorylation - immunology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Carrier Proteins - immunology | Dendritic Cells - metabolism | Trans-Activators - immunology | Fibroblasts - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Immunity, Innate - drug effects | Toll-Like Receptor 4 - genetics | Mice, Transgenic | Inflammation - immunology | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Forkhead Transcription Factors - genetics | Toll-Like Receptor 4 - metabolism | Carrier Proteins - genetics | Immunity, Innate - immunology | Animals | Carrier Proteins - metabolism | Proto-Oncogene Proteins c-akt - immunology | Signal Transduction - drug effects | Embryo, Mammalian - cytology | Embryo, Mammalian - immunology | Lipopolysaccharides - pharmacology | Inflammation - genetics | Fibroblasts - immunology | Trans-Activators - metabolism | Dendritic Cells - cytology | Fibroblasts - cytology | Forkhead Box Protein O1 | Mice | Transcription Factors | Toll-like Receptors (TLR) | mTOR Complex (mTORC) | Dendritic Cells | Signal Transduction | Innate Immunity | Rictor | Inflammation | Akt PKB | mTORC2 | FoxO1
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2008, Volume 118, Issue 12, pp. 3954 - 3965
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2012, Volume 8, Issue 1, p. e1002498
Human interferon (IFN)-inducible IFI16 protein, an innate immune sensor of intracellular DNA, modulates various cell functions, however, its role in regulating... 
ACTIVATION | TRANSCRIPTION | MICROBIOLOGY | INTRINSIC IMMUNITY | VIRAL-INFECTION | P53 | INTERFERON-INDUCIBLE PROTEIN | VIROLOGY | ENDOTHELIAL-CELLS | INFLAMMASOME | EXPRESSION | PARASITOLOGY | LATE PROMOTER | DNA, Viral - biosynthesis | Humans | Viral Proteins - immunology | Cercopithecus aethiops | Sp1 Transcription Factor - metabolism | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - metabolism | Sp1 Transcription Factor - immunology | Cytomegalovirus Infections - genetics | Phosphoproteins - metabolism | Viral Proteins - metabolism | DNA-Directed DNA Polymerase - genetics | Embryo, Mammalian - metabolism | Immunity, Innate - physiology | HEK293 Cells | Embryo, Mammalian - virology | Cytomegalovirus Infections - pathology | Nuclear Proteins - genetics | Response Elements - physiology | Cytomegalovirus - physiology | Vero Cells | Fibroblasts - metabolism | Fibroblasts - virology | Embryo, Mammalian - pathology | DNA-Directed DNA Polymerase - immunology | Viral Proteins - genetics | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Fibroblasts - pathology | DNA, Viral - immunology | Animals | Sp1 Transcription Factor - genetics | Embryo, Mammalian - immunology | Fibroblasts - immunology | Mice | DNA-Directed DNA Polymerase - metabolism | DNA, Viral - genetics | Virus Replication - physiology | Transcription factors | Viral genetics | Cytomegaloviruses | DNA | Physiological aspects | Genetic aspects | Research | Proteins | Cytomegalovirus | Microbiology | Cell cycle | Viruses | Gene expression | Experiments | Viral infections
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2010, Volume 207, Issue 1, pp. 247 - 261
Journal Article
Immunity, ISSN 1074-7613, 10/2018, Volume 49, Issue 4, pp. 640 - 653.e5
Tissue-resident mast cells are associated with many inflammatory and physiological processes. Although mast cells arise from the yolk sac, the exact ontogeny... 
Mast cell-committed progenitors | Yolk sac | Mast cells | Ontogeny | Hematopoietic stem cells | Erythro-myeloid progenitors | HOMEOSTASIS | MICROGLIA | YOLK-SAC | MACROPHAGES | HEMATOPOIETIC STEM-CELLS | MONOCYTES | MICE | IMMUNOLOGY | FETAL LIVER | PRECURSORS | FIBROBLASTS | Mast Cells - immunology | Myeloid Progenitor Cells - metabolism | Cells, Cultured | Erythroid Cells - metabolism | Connective Tissue - immunology | Mice, Transgenic | Erythroid Cells - cytology | Hematopoietic Stem Cells - metabolism | Erythroid Cells - immunology | Connective Tissue - metabolism | Hematopoietic Stem Cells - immunology | Animals | Embryo, Mammalian - embryology | Integrin beta Chains - immunology | Embryo, Mammalian - cytology | Embryo, Mammalian - immunology | Hematopoietic Stem Cells - cytology | Myeloid Progenitor Cells - immunology | Mast Cells - metabolism | Mast Cells - cytology | Myeloid Progenitor Cells - cytology | Integrin beta Chains - metabolism | Cell Lineage - immunology | Medical colleges | Diastereomers | Integrins | Mucosa | Homeostasis | Tissues | Immunity | Experiments | Connective tissues | Heterogeneity | Embryogenesis | Cell fate | Rodents | Bone marrow | Physiology | Pleural cavity | Yolk | Inflammation | Gene expression | Embryos | Esophagus | Hemopoiesis | Embryonic growth stage | Histamine | Place preferences | Stem cells
Journal Article