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Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2011, Volume 20, Issue 1, pp. 19 - 32
Neural progenitors self-renew and generate neurons throughout the central nervous system. Here, we uncover an unexpected regional specificity in the properties... 
STEM-CELLS | EMBRYONIC-DEVELOPMENT | IN-SITU HYBRIDIZATION | GENE-EXPRESSION | NEURONAL DIFFERENTIATION | SPINAL-CORD | NEUROGENESIS | DEVELOPMENTAL BIOLOGY | MIDBRAIN-HINDBRAIN BOUNDARY | VERTEBRATE SEGMENTATION | TRANSCRIPTION FACTOR | CELL BIOLOGY | Body Patterning - drug effects | Organ Specificity - drug effects | Cyclin D1 - metabolism | Embryo, Nonmammalian - cytology | Xenopus Proteins - genetics | Apoptosis - drug effects | Xenopus - genetics | Embryo, Nonmammalian - metabolism | Molecular Sequence Data | MicroRNAs - metabolism | Neural Stem Cells - cytology | Embryo, Nonmammalian - drug effects | Xenopus - embryology | Gene Knockdown Techniques | Neurogenesis - genetics | Rhombencephalon - cytology | Cell Differentiation - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Organ Specificity - genetics | Base Sequence | Neurogenesis - drug effects | Cell Survival - drug effects | Oligonucleotides, Antisense - pharmacology | Neural Stem Cells - drug effects | Tumor Suppressor Protein p53 - metabolism | Gene Expression Regulation - drug effects | Phenotype | Animals | Cyclin D1 - genetics | Cell Differentiation - drug effects | Prosencephalon - cytology | Xenopus Proteins - metabolism | Cell Proliferation - drug effects | MicroRNAs - genetics | Body Patterning - genetics | Neural Stem Cells - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Tumor proteins | Fibroblast growth factors | Messenger RNA | Index Medicus
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 30, pp. 7519 - 7532
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2011, Volume 691, pp. 271 - 279
The embryonic zebrafish model offers the power of whole-animal investigations (e.g., intact organism, functional homeostatic feedback mechanisms, and... 
Microinjections | Embryo, Nonmammalian - metabolism | Male | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Embryo, Nonmammalian - abnormalities | Animals | Water - chemistry | Animal Husbandry | Female | Models, Animal | Toxicity Tests - methods | Chorion - metabolism | Index Medicus | vertebrate | Zebrafish | development | in vivo | embryos | rapid screening
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1382 - 1395
Our aging society is confronted with a dramatic increase of patients suffering from tauopathies, which include Alzheimer disease and certain frontotemporal... 
DANIO-RERIO | MEDICINE, RESEARCH & EXPERIMENTAL | TRANSGENIC ZEBRAFISH | PHOSPHORYLATION | ALZHEIMERS-DISEASE | GLYCOGEN-SYNTHASE KINASE-3 | PAIRED HELICAL FILAMENTS | PROTEIN-TAU TAU | EXPRESSION | NEURODEGENERATIVE DISEASES | DEGENERATION | Neurons - pathology | Spinal Cord - metabolism | Humans | Embryo, Nonmammalian - metabolism | Tauopathies - pathology | tau Proteins - metabolism | Glycogen Synthase Kinase 3 beta | Embryo, Nonmammalian - drug effects | Motor Neurons - pathology | Escape Reaction | tau Proteins - genetics | Enzyme Inhibitors - pharmacokinetics | Larva - drug effects | Spinal Cord - pathology | Enzyme Inhibitors - chemistry | Cell Death | Drug Design | Molecular Structure | Neurons - metabolism | Larva - anatomy & histology | Phosphorylation - drug effects | Neurons - drug effects | Motor Neurons - drug effects | Disease Models, Animal | Drug Evaluation, Preclinical - methods | Glycogen Synthase Kinase 3 - chemistry | Animals, Genetically Modified | Embryo, Nonmammalian - pathology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Larva - metabolism | Enzyme Inhibitors - pharmacology | Models, Molecular | Zebrafish - genetics | Motor Neurons - metabolism | Synaptotagmins - metabolism | Embryo, Nonmammalian - abnormalities | Sequence Alignment | Tauopathies - metabolism | Animals | Glycogen Synthase Kinase 3 - genetics | Luminescent Proteins - genetics | Protein Conformation | Tauopathies - drug therapy | Luminescent Proteins - metabolism | Enzyme inhibitors | Cell death | Physiological aspects | Nervous system | Dosage and administration | Degeneration | Research | Diagnosis | Drug therapy | Index Medicus | Abridged Index Medicus | Technical Advance
Journal Article
Toxicology Letters, ISSN 0378-4274, 02/2013, Volume 217, Issue 1, pp. 50 - 58
Journal Article