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2007, Health and medical issues today, ISBN 9780313337635, xi, 203
Book
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 34, pp. 12426 - 12431
...). However, some induced pluripotent stem cells (iPSCs) exhibit defective differentiation and inappropriate maintenance of pluripotency features... 
Phenotypes | Induced pluripotent stem cells | Somatic cells | Stem cells | Retroviridae | Embryonic stem cells | Pluripotent stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | Epigenetics | Retrotransposon | Evolution | NONCODING RNA-ROR | ROADBLOCK | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | evolution | INDUCTION | epigenetics | IPS CELLS | PLURIPOTENT STEM-CELLS | PATHWAY | HUMAN FIBROBLASTS | retrotransposon | EXPRESSION | Octamer Transcription Factor-3 - physiology | Endogenous Retroviruses - physiology | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Endogenous Retroviruses - genetics | Pluripotent Stem Cells - virology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA, Viral - antagonists & inhibitors | RNA, Viral - genetics | SOXB1 Transcription Factors - genetics | Embryonic Stem Cells - virology | SOXB1 Transcription Factors - physiology | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Cellular Reprogramming - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - virology | Pluripotent Stem Cells - physiology | Kruppel-Like Transcription Factors - physiology | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | RNA, Long Noncoding - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Cellular Reprogramming - physiology | Epigenetic inheritance | Transcription factors | Retroviruses | Physiological aspects | Genetic research | Genetic aspects | Research | Cell differentiation | Gene expression | Virus research | Biological Sciences
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 1, p. e29597
Human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) provide new prospects for studying human neurodevelopment and modeling neurological disease... 
HUMAN ES | INHIBITION | FGF | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION CAPACITY | PRECURSORS | Oligonucleotide Array Sequence Analysis | Humans | Fibroblast Growth Factor 2 - pharmacology | Neurons - cytology | Gene Expression Profiling | Neural Stem Cells - cytology | Neuroepithelial Cells - cytology | Neuroglia - cytology | Neurons - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Cell Line | Pluripotent Stem Cells - cytology | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Differentiation - drug effects | Fluorescent Antibody Technique | Neuroglia - metabolism | Cell Proliferation - drug effects | Neuroepithelial Cells - metabolism | Epidermal Growth Factor - pharmacology | Neural Stem Cells - metabolism | Cluster Analysis | Medical research | Nervous system diseases | Epidermal growth factor | Neurons | Medicine, Experimental | Fibroblast growth factors | Comparative analysis | Embryonic stem cells | Neurophysiology | Neurosciences | Laboratories | Neurobiology | Embryo cells | Radial glial cells | Nervous system | Biochemistry | Neurodevelopmental disorders | Neuronal-glial interactions | Genotype & phenotype | Fibroblasts | Physiology | Growth factors | Fibroblast growth factor 2 | Fetuses | Embryos | Brain research | Stem cells | Comparative studies | Hindbrain | Bayesian analysis | Pluripotency
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and offer a cost-effective approach... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | toxicology | HUMAN NEOCORTEX | tissue engineering | DEVELOPMENTAL NEUROTOXICITY | differentiation | HUMAN BRAIN | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | FATTY-ACIDS | machine learning | CANCER | organoid | IN-VITRO | HUMAN CEREBRAL-CORTEX | MICROGLIA | GENE-EXPRESSION | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Biological Sciences
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 557, Issue 7703, pp. 106 - 111
... . From mouse blastocysts, it is possible to derive both trophoblast 2 and embryonic stem-cell lines 3 , which are in vitro analogues of the trophectoderm and embryonic compartments, respectively... 
Ectoderm/cytology | Humans | Nodal Protein/genetics | Transcriptome | Male | Uterus/cytology | Embryo Implantation | Kruppel-Like Factor 6/deficiency | Morphogenesis | Cell Self Renewal | Animals | Bone Morphogenetic Protein 4/pharmacology | Gene Expression Regulation, Developmental | Blastocyst/cytology | Female | Mice | Trophoblasts/cytology | Embryonic Stem Cells/cytology | TROPHOBLAST | TROPHECTODERM | GROUND-STATE | EMBRYO | MULTIDISCIPLINARY SCIENCES | MOUSE BLASTOCYST | GIANT-CELLS | EXPRESSION | BETA | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Uterus - metabolism | Nodal Protein - pharmacology | Nodal Protein - metabolism | Ectoderm - metabolism | Nodal Protein - genetics | Trophoblasts - cytology | Kruppel-Like Factor 6 - genetics | Trophoblasts - metabolism | Kruppel-Like Factor 6 - metabolism | Blastocyst - metabolism | Blastocyst - cytology | Kruppel-Like Factor 6 - deficiency | Bone Morphogenetic Protein 4 - pharmacology | Ectoderm - cytology | Uterus - cytology | Physiological aspects | Stem cell research | Embryonic stem cells | Blastocyst | Cell proliferation | Bone morphogenetic protein 4 | Transcription | Embryo cells | Stem cell transplantation | Implantation | Genomes | Blastocysts | Kinases | Gene expression | Embryos | Trophectoderm | Embryogenesis | Placenta | Allografts | Cysts | Compartments | Cooperation | Implants | Stem cells
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 62, Issue 3, pp. 581 - 589
Journal Article
eLife, ISSN 2050-084X, 2015, Volume 4, Issue 4, pp. 1 - 25
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 23, pp. 8518 - 8523
Progress in retinal-cell therapy derived from human pluripotent stem cells currently faces technical challenges that require the development of easy and standardized protocols... 
Epithelial cells | Induced pluripotent stem cells | Stem cells | Cell lines | Photoreceptors | Neural stem cells | Cultured cells | Pluripotent stem cells | Embryonic stem cells | Cellular differentiation | Cones | Retinal ganglion cells | Rods | DIRECTED DIFFERENTIATION | VESICLE-LIKE STRUCTURES | MULTIDISCIPLINARY SCIENCES | MOUSE | INDUCTION | FATE | PLURIPOTENT STEM-CELLS | cones | GROWTH | rods | retinal ganglion cells | GENERATION | EXPRESSION | REVEALS | Immunohistochemistry | Retinal Pigment Epithelium - metabolism | Homeodomain Proteins - metabolism | Humans | Multipotent Stem Cells - metabolism | Retinal Neurons - cytology | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Transfection | SOXB1 Transcription Factors - genetics | Adult | Cell Differentiation | Cell Culture Techniques | Dermis - cytology | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cell Line | Gene Expression | Nanog Homeobox Protein | Photoreceptor Cells - cytology | Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Retinal Neurons - metabolism | Multipotent Stem Cells - cytology | Octamer Transcription Factor-3 - metabolism | Photoreceptor Cells - metabolism | Fibroblasts - cytology | Microscopy, Fluorescence | Retinal Pigment Epithelium - cytology | Physiological aspects | Retina | Biological Sciences
Journal Article