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1. Full Text Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy
by Fabbrizi, Maria Rita and Meyer, Barbara and Misri, Sandeep and Raj, Suyash and Zobel, Cheri L and Hallahan, Dennis E and Sharma, Girdhar G
Cell death & disease, ISSN 2041-4889, 01/2018, Volume 9, Issue 5, pp. 492 - 14
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neural Stem Cells - radiation effects | Ataxia Telangiectasia Mutated Proteins - metabolism | Humans | Hematopoietic Stem Cells - pathology | Male | Mouse Embryonic Stem Cells - drug effects | Stem Cells - enzymology | Time Factors | Mouse Embryonic Stem Cells - enzymology | Mouse Embryonic Stem Cells - pathology | Proto-Oncogene Proteins c-akt - metabolism | Hematopoietic Stem Cells - radiation effects | Mouse Embryonic Stem Cells - radiation effects | Hematopoietic Stem Cells - drug effects | Protein Phosphatase 2 - antagonists & inhibitors | Signal Transduction | Tissue Culture Techniques | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Neural Stem Cells - drug effects | Stem Cells - radiation effects | Neural Stem Cells - enzymology | Neural Stem Cells - pathology | Radiation Tolerance - drug effects | Animals | DNA Repair | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Stem Cells - drug effects | Stem Cells - pathology | Mice | Oxazoles - pharmacology | Hematopoietic Stem Cells - enzymology | Apoptosis | Radiosensitivity | Cell survival | Phosphoprotein phosphatase | DNA damage | Stem cell transplantation | Radiation therapy | Embryos | DNA repair | Radioprotection | Hematopoietic stem cells | Hemopoiesis | Ionizing radiation | Allografts | Intestine | Cell death | Stem cells | Aging | Cancer | Phosphoprotein phosphatase 2A | Index Medicus
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2. Full Text Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells
by Zambidis, Elias T and Park, Tea Soon and Yu, Wayne and Tam, Ada and Levine, Michal and Yuan, Xuan and Pryzhkova, Marina and Péault, Bruno
Blood, ISSN 0006-4971, 11/2008, Volume 112, Issue 9, pp. 3601 - 3614
Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Embryonic Stem Cells - cytology | Humans | Thrombopoietin - administration & dosage | Yolk Sac - cytology | Yolk Sac - enzymology | Hematopoiesis - drug effects | Hematopoietic Stem Cells - immunology | Renin-Angiotensin System | Peptidyl-Dipeptidase A - metabolism | Colony-Forming Units Assay | Embryonic Stem Cells - immunology | Yolk Sac - immunology | Biomarkers - metabolism | Growth Substances - administration & dosage | Cell Line | Pluripotent Stem Cells - cytology | Pluripotent Stem Cells - immunology | Embryonic Stem Cells - enzymology | Pluripotent Stem Cells - enzymology | Drug Synergism | Endothelial Cells - immunology | Cell Differentiation - drug effects | Endothelial Cells - cytology | Hematopoietic Stem Cells - cytology | Endothelial Cells - enzymology | Hematopoietic Stem Cells - enzymology | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
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3. Full Text The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming
by Mansour, Abed Alfatah and Gafni, Ohad and Weinberger, Leehee and Zviran, Asaf and Ayyash, Muneef and Rais, Yoach and Krupalnik, Vladislav and Zerbib, Mirie and Amann-Zalcenstein, Daniela and Maza, Itay and Geula, Shay and Viukov, Sergey and Holtzman, Liad and Pribluda, Ariel and Canaani, Eli and Horn-Saban, Shirley and Amit, Ido and Novershtern, Noa and Hanna, Jacob H
Nature (London), ISSN 0028-0836, 08/2012, Volume 488, Issue 7411, pp. 409 - 413
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Molecular and cellular biology | Molecular genetics | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Male | Histone Demethylases - genetics | Gene Knockdown Techniques | Nuclear Proteins - deficiency | HEK293 Cells | Fibroblasts | Female | Germ Cells - metabolism | Induced Pluripotent Stem Cells - cytology | Nuclear Proteins - genetics | Cellular Reprogramming - genetics | Induced Pluripotent Stem Cells - metabolism | Biocatalysis | Induced Pluripotent Stem Cells - enzymology | Transgenes - genetics | Embryonic Stem Cells - enzymology | Nuclear Proteins - metabolism | Germ Cells - enzymology | Mice, Knockout | Cell Lineage | Histone Demethylases - metabolism | Animals | Alleles | Mice | Histone Demethylases - deficiency | Cellular Reprogramming - physiology | Chimera | Physiological aspects | Enzymes | Epigenetic inheritance | Genetic aspects | Germ cells | Research | Proteins | Epigenetics | Cell culture | Genomes | Stem cells | Index Medicus
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4. Full Text The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
by Boroviak, Thorsten and Loos, Remco and Bertone, Paul and Smith, Austin and Nichols, Jennifer
Nature cell biology, ISSN 1465-7392, 2014, Volume 16, Issue 6, pp. 513 - 528
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Cell Proliferation | Gene Expression Profiling | Embryo Culture Techniques | Extracellular Signal-Regulated MAP Kinases - metabolism | Mice, 129 Strain | Gene Expression Regulation, Developmental | Mice, Inbred CBA | Cell Differentiation | Clone Cells | Germ Layers - cytology | Germ Layers - enzymology | Biomarkers - metabolism | Cell Line | Mice, Inbred C57BL | Transcription Factors - genetics | Blastocyst Inner Cell Mass - cytology | Embryo Implantation | Gestational Age | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Lineage | Phenotype | Animals | Blastocyst Inner Cell Mass - metabolism | Mice | Laminin - metabolism | Embryonic development | Cell research | Cellular control mechanisms | Physiological aspects | Research | Embryonic stem cells | Identification and classification | Index Medicus
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5. Full Text Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
by Jennifer Nichols and Jose Silva and Mila Roode and Austin Smith
Development, ISSN 0950-1991, 10/2009, Volume 136, Issue 19, pp. 3215 - 3222
Hypoblast | Mouse | Epiblast | Pluripotency | Blastocyst | Erk | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Embryonic Stem Cells - cytology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Embryo Culture Techniques | Extracellular Signal-Regulated MAP Kinases - metabolism | Mice, Inbred CBA | Female | Benzamides - pharmacology | Germ Layers - cytology | Cell Differentiation - physiology | Germ Layers - enzymology | Germ Layers - drug effects | Pluripotent Stem Cells - cytology | Mice, Inbred C57BL | Blastocyst Inner Cell Mass - drug effects | Embryonic Development - physiology | Rats | Embryonic Stem Cells - enzymology | Pluripotent Stem Cells - enzymology | Blastocyst Inner Cell Mass - cytology | Blastocyst Inner Cell Mass - enzymology | Leukemia Inhibitory Factor - pharmacology | Pregnancy | Pyrroles - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Pluripotent Stem Cells - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Embryonic Development - drug effects | Index Medicus
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6. Full Text Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties
by Wang, Jing and Lu, Fei and Ren, Qi and Sun, Hong and Xu, Zhengshuang and Lan, Rongfeng and Liu, Yuqing and Ward, David and Quan, Junmin and Ye, Tao and Zhang, Hui
Cancer research (Chicago, Ill.), ISSN 0008-5472, 12/2011, Volume 71, Issue 23, pp. 7238 - 7249
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Neoplasms - metabolism | Embryonic Stem Cells - metabolism | NIH 3T3 Cells | Histone Demethylases - antagonists & inhibitors | Histone Demethylases - biosynthesis | Humans | Octamer Transcription Factor-3 - biosynthesis | Histone Demethylases - genetics | Octamer Transcription Factor-3 - genetics | Pluripotent Stem Cells - pathology | Epigenomics - methods | RNA Interference | SOXB1 Transcription Factors - genetics | Sensitivity and Specificity | HEK293 Cells | Antineoplastic Agents - pharmacology | Neoplasms - enzymology | Embryonic Stem Cells - enzymology | Pluripotent Stem Cells - enzymology | SOXB1 Transcription Factors - biosynthesis | Neoplasms - drug therapy | Pluripotent Stem Cells - metabolism | Animals | Methylation - drug effects | Pluripotent Stem Cells - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | HeLa Cells | Histones - metabolism | Neoplasms - pathology | Index Medicus | Histone H3 Methylation at K4 (H3K4) | Cancer Stem Cell | Pluripotent Cancer Cell | KDM1 | LSD1 | Histone Demethylase
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7. Full Text Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
by Mayle, Allison and Yang, Liubin and Rodriguez, Benjamin and Zhou, Ting and Chang, Edmund and Curry, Choladda V and Challen, Grant A and Li, Wei and Wheeler, David and Rebel, Vivienne I and Goodell, Margaret A
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 4, pp. 629 - 638
Life Sciences & Biomedicine | Hematology | Science & Technology | Promoter Regions, Genetic | DNA, Neoplasm - metabolism | Hematologic Neoplasms - enzymology | Hematologic Neoplasms - pathology | Cell Transformation, Neoplastic - metabolism | DNA (Cytosine-5-)-Methyltransferases | Mice, Knockout | DNA Methylation | Animals | Cell Transformation, Neoplastic - genetics | Hematologic Neoplasms - genetics | Mice | DNA, Neoplasm - genetics | Cell Transformation, Neoplastic - pathology | Hematopoietic Stem Cells - enzymology | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
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8. Full Text The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine
by Etchegaray, Jean-Pierre and Chavez, Lukas and Huang, Yun and Ross, Kenneth N and Choi, Jiho and Martinez-Pastor, Barbara and Walsh, Ryan M and Sommer, Cesar A and Lienhard, Matthias and Gladden, Adrianne and Kugel, Sita and Silberman, Dafne M and Ramaswamy, Sridhar and Mostoslavsky, Gustavo and Hochedlinger, Konrad and Goren, Alon and Rao, Anjana and Mostoslavsky, Raul
Nature cell biology, ISSN 1465-7392, 05/2015, Volume 17, Issue 5, pp. 545 - 557
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cytosine - analogs & derivatives | 5-Methylcytosine - analogs & derivatives | Homeodomain Proteins - metabolism | Humans | Mice, 129 Strain | Sirtuins - deficiency | Neurogenesis | SOXB1 Transcription Factors - metabolism | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | Transfection | RNA Interference | SOXB1 Transcription Factors - genetics | Cytosine - metabolism | Gene Expression Regulation, Developmental | Cell Differentiation | Acetylation | Sirtuins - genetics | Proto-Oncogene Proteins - metabolism | Induced Pluripotent Stem Cells - enzymology | Nanog Homeobox Protein | Teratoma - enzymology | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Chromatin Assembly and Disassembly | Embryonic Stem Cells - enzymology | Genotype | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Homeodomain Proteins - genetics | Mice, Knockout | Cell Lineage | Phenotype | Teratoma - pathology | Animals | Embryonic Stem Cells - transplantation | Octamer Transcription Factor-3 - metabolism | Embryonic Stem Cells - pathology | Histones - metabolism | Sirtuins - metabolism | Enzymes | Hydrolases | Genetic aspects | Properties | Embryonic stem cells | Cell differentiation | Index Medicus
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9. Full Text Role of Heme Oxygenase-1 in Postnatal Differentiation of Stem Cells: A Possible Cross-Talk with MicroRNAs
by Kozakowska, Magdalena and Szade, Krzysztof and Dulak, Jozef and Jozkowicz, Alicja
Antioxidants & redox signaling, ISSN 1523-0864, 04/2014, Volume 20, Issue 11, pp. 1827 - 1850
Forum Review Articles | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Osteoblasts - enzymology | Signal Transduction | Humans | Neoplasms - enzymology | Neural Stem Cells - physiology | Embryonic Stem Cells - enzymology | Neural Stem Cells - enzymology | Embryonic Stem Cells - physiology | Animals | Hematopoiesis | Heme Oxygenase-1 | Cell Differentiation | Osteoclasts - enzymology | MicroRNAs - physiology | Neoplasms - pathology | Oxidases | Stem cell research | Influence | MicroRNA | Research | Index Medicus | Forum Review
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