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1. Full Text Pou5f1 Transcription Factor Controls Zygotic Gene Activation In Vertebrates
by Manuel Leichsenring and Julia Maes and Rebecca Mössner and Wolfgang Driever and Daria Onichtchouk
Science, ISSN 0036-8075, 8/2013, Volume 341, Issue 6149, pp. 1005 - 1009
The development of multicellular animals is initially controlled by maternal gene products deposited in the oocyte. During the maternal-to-zygotic transition,... 
Vertebrates | Transcription factors | Chromatin | Genes | Drosophila | REPORTS | Stem cells | Genomes | Embryos | Binding sites | Gene activation | TRANSITION | ZEBRAFISH | EVOLUTION | ENDODERM FORMATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | REGIONS | REGULATORY NETWORK | PLURIPOTENCY | EXPRESSION | DROSOPHILA | Pluripotent Stem Cells - cytology | Zebrafish Proteins - metabolism | Pluripotent Stem Cells - physiology | Transcriptional Activation | Zygote - metabolism | DNA Polymerase II - metabolism | Zebrafish - embryology | Zebrafish - genetics | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Animals | Gene Expression Regulation, Developmental | Octamer Transcription Factor-3 - metabolism | Xenopus Proteins - metabolism | Zebrafish Proteins - genetics | Binding Sites | Physiological aspects | Genetic aspects | Research | Gene expression | Fracture mechanics | Zebrafish | Evolution | Cleavage | Activation | Mammals
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2. Full Text Gene activation by bioactive glasses
by Jell, G and Stevens, M M
Journal of Materials Science: Materials in Medicine, ISSN 0957-4530, 11/2006, Volume 17, Issue 11, pp. 997 - 1002
Bioactive glasses have been shown to regulate gene expression in both hard and soft tissue repair. New resorbable bioactive glass constructs are now being... 
Polymer Sciences | Chemistry | Ceramics, Glass, Composites, Natural Methods | Metallic Materials | Surfaces and Interfaces, Thin Films | Biomaterials | Characterization and Evaluation Materials | IONIC-DISSOLUTION PRODUCTS | MATERIALS SCIENCE, BIOMATERIALS | MESSENGER-RNA | BONE-FORMATION | ENGINEERING, BIOMEDICAL | EMBRYONIC STEM-CELLS | ENDOTHELIAL-CELLS | HUMAN FIBROBLASTS | SMOOTH-MUSCLE-CELLS | ALKALINE-PHOSPHATASE EXPRESSION | OSTEOBLASTS IN-VITRO | BETA-GLYCEROPHOSPHATE | Gene Expression Regulation - drug effects | Cell Line | Animals | Humans | Transcriptional Activation | Glass | Biocompatible Materials - pharmacology | Ceramics - pharmacology | Gene expression | Surface chemistry
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3. Full Text Minor zygotic gene activation is essential for mouse preimplantation development
by Abe, Ken-ichiro and Funaya, Satoshi and Tsukioka, Dai and Kawamura, Machika and Suzuki, Yutaka and Suzuki, Masataka G and Schultz, Richard M and Aoki, Fugaku
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 29, pp. E6780 - E6788
In mice, transcription initiates at the mid-one-cell stage and transcriptional activity dramatically increases during the two-cell stage, a process called... 
Preimplantation mouse embryo | Minor zygotic gene activation | Gene expression | Maternal-to-zygotic transition | RNA-POLYMERASE-II | maternal-to-zygotic transition | preimplantation mouse embryo | HISTONE MODIFICATION | STEM-CELLS | MULTIDISCIPLINARY SCIENCES | MAMMALIAN DEVELOPMENT | minor zygotic gene activation | DNA-REPLICATION | MESSENGER-RNA | EMBRYO | IN-VIVO | EXPRESSION | gene expression | MICROARRAY DATA | Animals | Zygote - cytology | Blastocyst - metabolism | Gene Expression Regulation, Developmental - drug effects | Zygote - metabolism | Embryonic Development - physiology | Blastocyst - cytology | Mice | Dichlororibofuranosylbenzimidazole - pharmacology | Histones - metabolism | Embryonic Development - drug effects | Gene Expression Regulation, Developmental - physiology | Embryonic development | Genetic aspects | Genetic transcription | Observations | Biological Sciences | PNAS Plus
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4. Full Text Nac1 facilitates pluripotency gene activation for establishing somatic cell reprogramming
by Choi, Hwan and Park, Hyeok Ju and Kim, Jongpil and Kim, Hongwon and Kim, Junyeop and Lee, Yong Kyu
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019, Volume 518, Issue 2, pp. 253 - 258
Transcription factors play a central role in pluripotency transcription circuitry for establishing pluripotent reprogramming. Master transcription factors... 
Induced pluripotent stem cell | Embryonic stem cell | Nucleus accumbens-1 | Pluripotency | Anopheles | Genes | Genomics | Genetic transcription | DNA binding proteins | Embryonic stem cells | Biomedical engineering
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5. Full Text Opposing Roles for the lncRNA Haunt and Its Genomic Locus in Regulating HOXA Gene Activation during Embryonic Stem Cell Differentiation
by Yin, Yafei and Yan, Pixi and Lu, Jinlong and Song, Guang and Zhu, Yangyang and Zhu, Heng and Li, Zhaohui and Zhao, Yi and Shen, Bin and Shen, Xiaohua and Huang, Xingxu and Orkin, Stuart H
Cell Stem Cell, ISSN 1934-5909, 05/2015, Volume 16, Issue 5, pp. 504 - 516
Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific... 
NONCODING RNA | LINCRNAS | IDENTITY | EVOLUTION | CHROMATIN INTERACTOME | TRANSCRIPTION | SELF-RENEWAL | PLURIPOTENCY | ENHANCERS | EXPRESSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Line | Homeodomain Proteins - metabolism | Transcriptional Activation | Gene Expression Regulation | Genetic Loci - genetics | Chromatin Assembly and Disassembly | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | Homeodomain Proteins - genetics | DNA - genetics | Cell Differentiation - genetics | Animals | CRISPR-Cas Systems | Enhancer Elements, Genetic - genetics | Mice | Genome | RNA, Long Noncoding - metabolism
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6. Full Text Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis
by Yu, Duonan and Yu, Ming and Riva, Laura and Xie, Huafeng and Schindler, Yocheved and Moran, Tyler B and Cheng, Yong and Hardison, Ross and Weiss, Mitchell J and Orkin, Stuart H and Bernstein, Bradley E and Fraenkel, Ernest and Cantor, Alan B
Molecular Cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 4, pp. 682 - 695
The transcription factor GATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context. Yet its... 
DNA | MOUSE DEVELOPMENT | TRANSCRIPTION FACTOR GATA-1 | STEM-CELLS | DNA-BINDING FACTOR | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ZINC-FINGER | IN-VIVO | MAMMALIAN-CELLS | ERYTHROID MATURATION | EXPRESSION | CELL BIOLOGY | Chromatin - metabolism | Transcriptional Activation - genetics | Biotinylation | Computational Biology | Gene Silencing | Genome - genetics | Molecular Sequence Data | Gene Expression Profiling | Gene Expression Regulation, Leukemic | Polycomb-Group Proteins | GATA1 Transcription Factor - metabolism | Sequence Analysis, DNA | Regulatory Sequences, Nucleic Acid - genetics | Animals | Chromatin Immunoprecipitation | Streptavidin - metabolism | Base Sequence | Cell Line, Tumor | Protein Binding | Biotin - metabolism | Mice | Models, Genetic | Binding Sites | Repressor Proteins - metabolism | Computer science | Medical colleges | Chromatin | Anopheles | Genomics | Genetic research | Medical law | Gene expression | Artificial intelligence | erythroid | GATA-1 | ChIP-seq | Polycomb | Zbtb7a
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7. Full Text SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis
by Alejandro Amador-Arjona and Flavio Cimadamore and Chun-Teng Huang and Rebecca Wright and Susan Lewis and Fred H. Gage and Alexey V. Terskikh
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2015, Volume 112, Issue 15, pp. E1936 - E1945
Newborn granule neurons generated from neural progenitor cells (NPCs) in the adult hippocampus play a key role in spatial learning and pattern separation.... 
SOX2 | Epigenetics | Neurogenesis | PROGENITOR CELLS | ANOPHTHALMIA SYNDROME | MULTIDISCIPLINARY SCIENCES | ADULT DENTATE GYRUS | MOUSE | SELF-RENEWAL | PROLIFERATION | epigenetics | EMBRYONIC STEM-CELLS | IN-VIVO | neurogenesis | NEURONS | DIFFERENTIATION | Cell Cycle - genetics | Epigenesis, Genetic | SOXB1 Transcription Factors - deficiency | Transcriptional Activation | Promoter Regions, Genetic - genetics | SOXB1 Transcription Factors - metabolism | Neurogenesis - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | SOXB1 Transcription Factors - genetics | Neurons - physiology | Neurons - metabolism | Animals, Newborn | Cell Proliferation - genetics | Gene Expression | Basic Helix-Loop-Helix Transcription Factors - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Hippocampus - cytology | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Blotting, Western | Mice, Knockout | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Patch-Clamp Techniques | Animals | Protein Binding | Neural Stem Cells - metabolism | Microscopy, Fluorescence | Influence | Transcription factors | Hippocampus (Brain) | Research | Analysis | Biological Sciences | PNAS Plus
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8. Full Text Synchronous and Stochastic Patterns of Gene Activation in the Drosophila Embryo
by Alistair N. Boettiger and Michael Levine
Science, ISSN 0036-8075, 7/2009, Volume 325, Issue 5939, pp. 471 - 473
Drosophila embryogenesis is characterized by rapid transitions in gene activity, whereby crudely distributed gradients of regulatory proteins give way to... 
Ectoderm | Embryogenesis | Transcription factors | Genes | Drosophila | Mesoderm | Reports | Gene expression | Embryos | Gene activation | Genetic hybridization | MESODERM | PROTEIN | RNA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | CONSEQUENCES | NOISE | EXPRESSION | GRADIENT | MELANOGASTER | DORSAL | Genes, Insect | Animals | Stochastic Processes | Gene Expression Regulation, Developmental | Transcriptional Activation | Embryo, Nonmammalian | RNA Polymerase II - metabolism | Drosophila - genetics | Embryonic development | Growth | Stochastic processes | Genetic aspects | Research | Insects | Evolution & development | DNA-directed RNA polymerase
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9. Full Text INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-Renewal, Reprogramming, and Blastocyst Development
by Wang, Li and Du, Ying and Ward, James M and Shimbo, Takashi and Lackford, Brad and Zheng, Xiaofeng and Miao, Yi-liang and Zhou, Bingying and Han, Leng and Fargo, David C and Jothi, Raja and Williams, Carmen J and Wade, Paul A and Hu, Guang
Cell Stem Cell, ISSN 1934-5909, 05/2014, Volume 14, Issue 5, pp. 575 - 591
The master transcription factors play integral roles in the pluripotency transcription circuitry of embryonic stem cells (ESCs). How they selectively activate... 
OCT4 | CHROMATIN REMODELING COMPLEX | MEDIATOR | TRANSCRIPTIONAL NETWORK | MECHANISMS | DIFFERENTIATION | EXPRESSION | OCCUPANCY | GENOME | RNAI SCREEN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Line | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Pluripotent Stem Cells - cytology | Blastocyst - metabolism | Blastocyst - cytology | Chromatin Assembly and Disassembly - genetics | Embryo, Mammalian - metabolism | Octamer Transcription Factor-3 - genetics | Pluripotent Stem Cells - metabolism | Proteins - genetics | DNA Helicases - metabolism | Animals | Proteins - metabolism | Embryo, Mammalian - cytology | Models, Biological | Octamer Transcription Factor-3 - metabolism | Female | Mice | In Vitro Techniques | Cell Differentiation - physiology | DNA Helicases - genetics | Chromatin Assembly and Disassembly - physiology
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10. Full Text Minor zygotic gene activation is essential for mouse preimplantation development
by Abe, Ken-Ichim and Funaya, Satoshi and Tsukioka, Dai and Kawamura, Machika and Suzuki, Yutaka and Suzuki, Masataka G and Schultz, Richard M and Aoki, Fugaku
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 07/2018, Volume 115, Issue 29, p. 7463
Embryonic development | Genetic aspects | Gene expression | Observations
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11. Full Text Polycomb Group Protein Displacement and Gene Activation through MSK-Dependent H3K27me3S28 Phosphorylation
by Gehani, Simmi Suman and Agrawal-Singh, Shuchi and Dietrich, Nikolaj and Christophersen, Nicolaj Strøyer and Helin, Kristian and Hansen, Klaus
Molecular Cell, ISSN 1097-2765, 09/2010, Volume 39, Issue 6, pp. 886 - 900
Epigenetic regulation of chromatin structure is essential for the expression of genes determining cellular specification and function. The Polycomb repressive... 
HISTONE METHYLTRANSFERASE ACTIVITY | MOUSE DEVELOPMENT | TRANSCRIPTIONAL ACTIVATION | EPIGENETIC MARK | STEM-CELLS | METHYLATION | CHROMATIN | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMOSOME CONDENSATION | H3 VARIANTS | CELL BIOLOGY | Phosphorylation - physiology | Chromatin - metabolism | Embryonic Stem Cells - metabolism | Gene Expression - drug effects | Gene Expression - genetics | Humans | Neurons - cytology | Protein Transport - physiology | Promoter Regions, Genetic - genetics | Cell Differentiation - genetics | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Peptides - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - antagonists & inhibitors | Antibodies - immunology | DNA Damage - genetics | Lysine - metabolism | Neurons - metabolism | Repressor Proteins - metabolism | Activating Transcription Factor 3 - genetics | Fibroblasts - metabolism | DNA Damage - drug effects | Histones - immunology | Gene Expression Regulation - physiology | Polycomb-Group Proteins | Serine - metabolism | Mitosis - physiology | Cell Differentiation - drug effects | Fibroblasts - drug effects | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Cell Line, Tumor | Anisomycin - pharmacology | HeLa Cells | Histones - metabolism | Methylation | Chromatin - genetics | Protein Binding - physiology | Cell research | Chromatin | Lysine | Gene expression | Embryonic stem cells | Phosphotransferases | Tretinoin
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12. Full Text Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming
by Liang, Gaoyang and He, Jin and Zhang, Yi
Nature Cell Biology, ISSN 1465-7392, 05/2012, Volume 14, Issue 5, pp. 457 - 466
Transcription-factor-directed reprogramming from somatic cells to induced pluripotent stem cells (iPSCs) is by nature an epigenetic process of cell fate... 
OCT4 | DOMAIN | MOUSE EMBRYONIC FIBROBLASTS | PATHWAY | SMALL-MOLECULE COMPOUNDS | STATE | E-CADHERIN | INDUCTION | IRF6 | LOCUS | CELL BIOLOGY | Promoter Regions, Genetic | Animals | Cell Proliferation | F-Box Proteins - physiology | Pluripotent Stem Cells - cytology | Epigenesis, Genetic | Gene Expression Regulation | Jumonji Domain-Containing Histone Demethylases - physiology | Polymerase Chain Reaction | Mice | Physiological aspects | Transcription factors | Genetic aspects | Research | Stem cells
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13. Full Text Gene activation-associated long noncoding RNAs function in mouse preimplantation development
by Hamazaki, Nobuhiko and Uesaka, Masahiro and Nakashima, Kinichi and Agata, Kiyokazu and Imamura, Takuya
Development (Cambridge), ISSN 0950-1991, 2015, Volume 142, Issue 5, pp. 910 - 920
In mice, zygotic activation occurs for a wide variety of genes, mainly at the 2-cell stage. Long noncoding RNAs (lncRNAs) are increasingly being recognized as... 
DNA demethylation | Epigenetic regulation | Early mouse preimplantation development | Long noncoding RNA | Zygotic gene activation | Pluripotency | APOPTOSIS | METHYLATION | DYNAMIC CPG | TRANSCRIPTION | DEVELOPMENTAL BIOLOGY | BLASTOCYST | PATERNAL GENOME | PROMOTERS | EMBRYONIC STEM-CELLS | EXPRESSION | Pluripotent Stem Cells - cytology | Oocytes - metabolism | Blastocyst - metabolism | Blastocyst - physiology | Data Mining | Male | DNA Methylation - genetics | RNA, Long Noncoding - genetics | Pluripotent Stem Cells - metabolism | Pregnancy | Animals | Epigenesis, Genetic - genetics | Polymerase Chain Reaction | Female | Mice | Spermatozoa - cytology
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14. Full Text Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation
by Zhenfei Li and Fen Nie and Sheng Wang and Lin Li and Mark T. Groudine
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 8, pp. 3116 - 3123
Histone methylation has an important role in transcriptional regulation. However, unlike H3K4 and H3K9 methylation, the role of H4K20 monomethylation... 
Chromatin | Phenotypes | Messenger RNA | HEK293 cells | Transcriptional activation | Genes | Histones | Methylation | Gene expression | Embryos | Zebrafish embryonic development | Epigenetic regulation | COMPLEX |