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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 51, pp. E7128 - E7137
This paper reviews the developments that have occurred in the field of human genetics of infectious diseases from the second half of the 20th century onward.... 
Pediatrics | Immunology | Infectious diseases | Human genetics | Primary immunodeficiency | human genetics | LINKED LYMPHOPROLIFERATIVE SYNDROME | CALMETTE-GUERIN INFECTION | RECEPTOR BETA-1 DEFICIENCY | MULTIDISCIPLINARY SCIENCES | infectious diseases | ANHIDROTIC ECTODERMAL DYSPLASIA | T-CELL IMMUNODEFICIENCY | CHRONIC MUCOCUTANEOUS CANDIDIASIS | PRIMARY IMMUNODEFICIENCY DISEASES | PYOGENIC BACTERIAL-INFECTIONS | pediatrics | primary immunodeficiency | immunology | HERPES-SIMPLEX ENCEPHALITIS | INHERITED CARD9 DEFICIENCY | Encephalitis, Herpes Simplex - immunology | Humans | Genetic Diseases, Inborn - genetics | Lymphoproliferative Disorders - immunology | Mycobacterium Infections - immunology | Young Adult | Pneumococcal Infections - immunology | Mycobacterium Infections - genetics | Pneumococcal Infections - genetics | Complement System Proteins - genetics | Encephalitis, Herpes Simplex - genetics | Epidermodysplasia Verruciformis - immunology | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Child | Genetic Predisposition to Disease | Neisseria - immunology | Tinea - immunology | Infection - immunology | Candidiasis, Chronic Mucocutaneous - genetics | Malaria - immunology | Candidiasis, Chronic Mucocutaneous - immunology | Genetic Diseases, Inborn - immunology | Tinea - genetics | Epidermodysplasia Verruciformis - genetics | Lymphoproliferative Disorders - genetics | Infection - genetics | Models, Immunological | Neisseria - pathogenicity | Influenza, Human - genetics | Interferon-gamma - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Models, Genetic | Malaria - genetics | Influenza, Human - immunology | Development and progression | Genetic aspects | Disease susceptibility | Immune response | Communicable diseases | Biological Sciences | PNAS Plus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24745
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, p. e10537
West Nile virus, first identified within the United States in 1999, has since spread across the continental states and infected birds, humans and domestic... 
2'-5'-OLIGOADENYLATE SYNTHETASE GENE | ACTIVATION | VIRUS-INFECTION | PATHOGENICITY | 2',5'-OLIGOADENYLATE SYNTHETASE | MOLECULAR-WEIGHT INHIBITOR | INTERFERON-TREATED CELLS | BIOLOGY | FREE PROTEIN-SYNTHESIS | REGULATORY ELEMENTS | EXPRESSION | Horse Diseases - enzymology | Genetic Predisposition to Disease | West Nile Fever - genetics | West Nile Fever - virology | Interferons - pharmacology | Horses - genetics | Humans | Horse Diseases - virology | Promoter Regions, Genetic - genetics | Case-Control Studies | 2',5'-Oligoadenylate Synthetase - genetics | Hep G2 Cells | Haplotypes - genetics | Animals | West Nile Fever - enzymology | Luciferases | Alleles | Polymorphism, Single Nucleotide - genetics | West Nile Fever - veterinary | Horses - virology | Fibroblasts - metabolism | Horse Diseases - genetics | Encephalitis | Medical research | Genes | West Nile fever | Medicine, Experimental | Genetic aspects | Disease susceptibility | Interferon | Biological response modifiers | Gene expression | Genetic polymorphisms | Health care | Populations | Zoology | Viruses | Infections | Veterinary medicine | Domestic animals | Proteins | Disease resistance | Hepatitis | Clusters | Fibroblasts | Ataxia | Population | Immune system | Cytokines | Animal sciences | Birds | Resistance factors | Studies | Mosquitoes | West Nile virus | Horses | Mice | Mutation | Viral infections
Journal Article
Nature, ISSN 0028-0836, 07/2007, Volume 448, Issue 7149, pp. 39 - 43
A major impediment in the treatment of neurological diseases is the presence of the blood - brain barrier, which precludes the entry of therapeutic molecules... 
IN-VIVO DELIVERY | VIRUS | TRANSPORTERS | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR DELIVERY | CELL-PENETRATING PEPTIDES | GENE-THERAPY | RECEPTORS | MODIFIED SIRNAS | BRAIN | INHIBITS TUMOR-GROWTH | RNA, Small Interfering - genetics | Superoxide Dismutase - genetics | Encephalitis Virus, Japanese | Humans | Glycoproteins - metabolism | Brain - virology | Molecular Sequence Data | Green Fluorescent Proteins - genetics | Viral Proteins - metabolism | Drug Delivery Systems | Brain - metabolism | Lentivirus - genetics | Viral Proteins - administration & dosage | Neurons - metabolism | Glycoproteins - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Neurons - virology | Rabies virus - physiology | Receptors, Nicotinic - metabolism | Mice, Inbred C57BL | Oligopeptides - genetics | Gene Silencing | Viral Proteins - genetics | Recombinant Proteins - genetics | Mice, SCID | Genetic Vectors - genetics | Glycoproteins - administration & dosage | Recombinant Proteins - administration & dosage | Rabies virus - genetics | Animals | Encephalitis, Japanese - prevention & control | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | HeLa Cells | Liposomes | Superoxide Dismutase-1 | RNA, Small Interfering - administration & dosage | Blood-Brain Barrier | RNA, Small Interfering - metabolism | Brain cells | Research | Brain | Nervous system | Amino acids | Peptides | Neurological disorders | Blood | Blood-brain barrier | Ribonucleic acids | Cytokines | Genes | Central nervous system
Journal Article
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 10/2011, Volume 204, Issue 7, pp. 1031 - 1037
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 164 - 168
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94946
Tick-borne encephalitis virus (TBEV) is transmitted to vertebrates by taiga or forest ticks through bites, inducing disease of variable severity. The reasons... 
IMMUNODEFICIENT MICE | DEPENDENT RNA-POLYMERASE | NONSTRUCTURAL PROTEIN NS1 | INFECTIOUS CDNA-CLONE | MULTIDISCIPLINARY SCIENCES | WEST-NILE-VIRUS | FUNCTIONAL-ANALYSIS | INTERFERON ANTAGONIST | DENGUE VIRUS | NUCLEOTIDE-SEQUENCES | CYCLIZATION SEQUENCES | Geography | Encephalitis Viruses, Tick-Borne - genetics | Genome, Viral - genetics | Humans | 3' Untranslated Regions - genetics | Molecular Sequence Data | 5' Untranslated Regions - genetics | Encephalitis Viruses, Tick-Borne - classification | Phylogeny | RNA Helicases - chemistry | Russia | Encephalitis Viruses, Tick-Borne - pathogenicity | Viral Nonstructural Proteins - chemistry | RNA, Viral - genetics | Virulence - genetics | Base Sequence | China | Capsid Proteins - chemistry | Encephalitis, Tick-Borne - virology | Serine Endopeptidases - genetics | RNA Helicases - genetics | Nucleic Acid Conformation | Genetic Structures | Protein Structure, Tertiary | Amino Acid Sequence | Models, Molecular | Viral Nonstructural Proteins - genetics | Serine Endopeptidases - chemistry | Encephalitis, Tick-Borne - blood | Sequence Homology, Amino Acid | Animals | RNA, Viral - chemistry | Amino Acid Substitution | Capsid Proteins - genetics | Control | Genetic aspects | Tick-borne encephalitis | Distribution | Capsid protein | Laboratories | Ticks | Bites | Amino acids | Viruses | Genomes | Amino acid substitution | Substitutes | Proteins | Clonal deletion | Phylogenetics | Clusters | Deletion | Genetic factors | Taiga | Strains (organisms) | Arachnids | Encephalitis | Pathogens | Mortality | Patients | Pathogenicity | Studies | Vertebrates | West Nile virus | Mutation | Budding
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 06/2014, Volume 24, pp. 116 - 126
Like most arthropod-borne viruses (arboviruses), chikungunya virus (CHIKV) is a RNA virus maintained in nature in an alternating cycle of replication between... 
Vector adaptation | Arbovirus evolution | Genome stability | Host alternation | INFECTIOUS DISEASES | EQUINE ENCEPHALITIS-VIRUS | INVERTEBRATE CELLS | WEST-NILE-VIRUS | RNA VIRUSES | MAMMALIAN-CELLS | SINDBIS VIRUS | AEDES-ALBOPICTUS | NATURALLY INFECTED MOSQUITOS | Chikungunya virus - genetics | Virus Replication - genetics | Genome, Viral - genetics | Insect Vectors - virology | Culicidae - virology | RNA, Viral - genetics | Interferon-alpha - genetics | Adaptation, Physiological - genetics | Base Sequence | Interferon-beta - genetics | Female | Chikungunya Fever | Cell Line | Cricetinae | Viral Envelope Proteins - genetics | Chikungunya virus - growth & development | Mice, Knockout | Point Mutation | Animals | Sequence Analysis, RNA | Chikungunya virus - classification | Host-Pathogen Interactions - genetics | Amino Acid Substitution - genetics | Mice | Evolution, Molecular | Virus diseases | Mosquitoes | Genetic aspects | Gene mutations | Viral Envelope Proteins/genetics | Culicidae/virology | Chikungunya virus/genetics | Chikungunya virus/classification | Life Sciences | Host-Pathogen Interactions/genetics | Interferon-alpha/genetics | Amino Acid Substitution/genetics | Chikungunya virus/growth & development | RNA, Viral/genetics | Interferon-beta/genetics | Insect Vectors/virology | Virus Replication/genetics | Adaptation, Physiological/genetics | Microbiology and Parasitology | Genome, Viral/genetics
Journal Article