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Journal Article
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 8, pp. 1533 - 1549
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e76495
Multiple sclerosis (MS) is a chronic autoimmune neuroinflammatory disease found mostly in young adults in the western world. Oxidative stress induced neuronal... 
IN-VITRO | INHIBITION | ACID | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | TAU | CENTRAL-NERVOUS-SYSTEM | BLOOD-BRAIN-BARRIER | EXPRESSION | SCLEROSIS PATIENTS | CELL-DEATH | Reactive Oxygen Species - metabolism | Triterpenes - pharmacology | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Demyelinating Diseases - metabolism | Glial Fibrillary Acidic Protein | Th1 Cells - metabolism | CD11b Antigen - genetics | Inflammation - metabolism | Th17 Cells - drug effects | Th17 Cells - metabolism | Inflammation - drug therapy | Apoptosis Regulatory Proteins - genetics | Female | Encephalomyelitis, Autoimmune, Experimental - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Cell Line | Th1 Cells - drug effects | Drugs, Chinese Herbal | Cytokines - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | RNA, Messenger - genetics | Multiple Sclerosis - genetics | Antioxidants - pharmacology | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | T-Box Domain Proteins - genetics | Disease Progression | Apoptosis Regulatory Proteins - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Animals | Nitric Oxide Synthase Type II - genetics | Mice | CD11b Antigen - metabolism | Oxidative Stress - drug effects | Multiple Sclerosis - drug therapy | Nitric Oxide Synthase Type II - metabolism | Saponins - pharmacology | Antioxidants | Oxidative stress | Nervous system diseases | Multiple sclerosis | Cytokines | Encephalomyelitis | T cells | Tumor proteins | Neurophysiology | Cell culture | Phosphorylation | Hydrogen peroxide | Bax protein | Bcl-2 protein | Laboratories | Pathogenesis | p53 Protein | Differentiation (biology) | Central nervous system | Lymphocytes T | Chinese medicine | Blood-brain barrier | Neurodegeneration | Rodents | Modulation | Cell cycle | Inhibition | Free radicals | Young adults | Inflammation | Gene expression | Cell differentiation | Experimental allergic encephalomyelitis | Nitric-oxide synthase | Molecular chains | Microglia | Tau protein | Nitric oxide | γ-Interferon | Adults | Infiltration | Apoptosis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 247 - 260
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2006, Volume 177, Issue 1, pp. 566 - 573
IL-17 is a proinflammatory cytokine that activates T cells and other immune cells to produce a variety of cytokines, chemokines, and cell adhesion molecules.... 
IFN-GAMMA GENE | MULTIPLE-SCLEROSIS | INTERFERON-GAMMA | MYELIN-OLIGODENDROCYTE GLYCOPROTEIN | CELL-DEFICIENT MICE | NONOBESE DIABETIC MICE | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | CENTRAL-NERVOUS-SYSTEM | T-CELL | IMMUNOLOGY | VERSUS-HOST-DISEASE | Lymph Nodes - pathology | Interleukin-17 - physiology | Encephalomyelitis, Autoimmune, Experimental - immunology | Molecular Sequence Data | Epitopes, T-Lymphocyte - administration & dosage | Adoptive Transfer | Autoantibodies - biosynthesis | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Peptide Fragments - immunology | Encephalomyelitis, Autoimmune, Experimental - genetics | Epitopes, T-Lymphocyte - immunology | Interferon-gamma - genetics | Interferon-gamma - deficiency | Amino Acid Sequence | Encephalomyelitis, Autoimmune, Experimental - pathology | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-17 - genetics | Lymph Nodes - metabolism | Myelin-Oligodendrocyte Glycoprotein | Up-Regulation - genetics | Interleukin-17 - biosynthesis | Interleukin-17 - deficiency | Lymph Nodes - immunology | Glycoproteins - administration & dosage | Mice, Knockout | Glycoproteins - immunology | Animals | CD4-Positive T-Lymphocytes - transplantation | Up-Regulation - immunology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Interferon-gamma - biosynthesis
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e85007
Multiple sclerosis (MS), characterized by chronic inflammation, demyelination, and axonal damage, is a complicated neurological disease of the human central... 
IMMUNE-RESPONSE | MCP-1 | MULTIPLE-SCLEROSIS | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | TISSUE | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | CCL2 | STROMAL CELLS | METALLOPROTEINASES | EXPRESSION | Humans | Adipose Tissue - cytology | Encephalomyelitis, Autoimmune, Experimental - immunology | Adipocytes - cytology | Transplantation, Autologous | Adipose Tissue - immunology | Mesenchymal Stromal Cells - immunology | Mesenchymal Stromal Cells - cytology | Treatment Failure | Female | Cell Differentiation | Encephalomyelitis, Autoimmune, Experimental - genetics | Cytokines - genetics | Adipocytes - immunology | Cytokines - immunology | Disease Models, Animal | Biomarkers - metabolism | Gene Expression | Encephalomyelitis, Autoimmune, Experimental - pathology | Mice, Inbred C57BL | Multiple Sclerosis - genetics | Multiple Sclerosis - therapy | Disease Progression | Encephalomyelitis, Autoimmune, Experimental - therapy | Animals | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Mice | Mesenchymal Stem Cell Transplantation | Medical research | Nervous system diseases | Multiple sclerosis | Encephalomyelitis | Analysis | Stem cells | Medicine, Experimental | Models | Inflammation | Transplantation | Animal models | Transplants & implants | Disease | Laboratories | Syngeneic grafts | Central nervous system | Cytology | Stem cell transplantation | Nervous system | Cell surface | Cell morphology | Proteins | Infusion | Keratin | Biomedical materials | Allografts | Immunology | Demyelination | Rodents | Bone marrow | Biocompatibility | Immune system | Autografts | Cytokines | Medical treatment | Experimental allergic encephalomyelitis | Whooping cough | Medicine | Studies | Brain research | Monocyte chemoattractant protein | Infiltration | Molecular biology | Differentiation | Chemokines | Monocyte chemoattractant protein 1
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2014, Volume 124, Issue 5, pp. 2009 - 2022
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2014, Volume 124, Issue 5, pp. 2188 - 2192
Taken orally, the drug dimethyl fumarate (DMF) has been shown to improve functional outcomes for patients with MS; however, it is unclear how DMF mediates a... 
NICOTINIC-ACID | MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS | PLACEBO-CONTROLLED PHASE-3 | ESTERS | GPR109A | CENTRAL-NERVOUS-SYSTEM | MICE | ORAL BG-12 | PSORIASIS | Physiological aspects | Esters | Care and treatment | Cell receptors | Encephalomyelitis | Health aspects | Studies | Spinal cord | Acids | Rodents | Migration | Gene expression | Experiments | Apoptosis
Journal Article