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Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 02/2010, Volume 107, Issue 6, pp. 2580 - 2585
.... These observations led us to ask further whether manipulation of the GABA pathway influences an animal model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE... 
T lymphocytes | Brain | Receptors | Cytokines | Neurons | Splenocytes | Central nervous system | Inflammation | Macrophages | Immune system | Experimental autoimmune encephalomyelitis | Neurotransmitter | Multiple sclerosis | Antigen-presenting cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antigen-Presenting Cells - cytology | Encephalomyelitis, Autoimmune, Experimental - metabolism | gamma-Aminobutyric Acid - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Interferon-gamma - metabolism | 4-Aminobutyrate Transaminase - metabolism | Antigen-Presenting Cells - physiology | Inflammation - metabolism | T-Lymphocytes - metabolism | GABA Plasma Membrane Transport Proteins - metabolism | T-Lymphocytes - drug effects | gamma-Aminobutyric Acid - immunology | Multiple Sclerosis - metabolism | Macrophages - physiology | Membrane Potentials - drug effects | Antigen-Presenting Cells - metabolism | Receptors, GABA - genetics | Mice, Inbred C57BL | Cells, Cultured | Myelin-Oligodendrocyte Glycoprotein | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Inflammation - immunology | Macrophages - cytology | Reverse Transcriptase Polymerase Chain Reaction | 4-Aminobutyrate Transaminase - genetics | Blotting, Western | GABA Plasma Membrane Transport Proteins - genetics | Interleukin-17 - metabolism | GABA Agents - pharmacology | Macrophages - metabolism | Myelin-Associated Glycoprotein - immunology | Patch-Clamp Techniques | Animals | Receptors, GABA - metabolism | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Multiple Sclerosis - immunology | Myelin Proteins | T-Lymphocytes - immunology | Inflammation - prevention & control | Mice | Autoimmunity | Encephalomyelitis | GABA | Development and progression | Research | Properties | Index Medicus | Biological Sciences | experimental autoimmune encephalomyelitis | antigen-presenting cells | neurotransmitter | multiple sclerosis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 9/2013, Volume 110, Issue 36, pp. 14735 - 14740
...) and its animal model experimental autoimmune encephalomyelitis. This disruption may precede and facilitate the infiltration of encephalitogenic T cells... 
T lymphocytes | Nervous system diseases | Demyelinating diseases | Tight junctions | Medical treatment | Central nervous system | Central nervous system diseases | Mice | Blood brain barrier | Endothelial cells | EAE | Enzastaurin | CNS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Claudin-5 - metabolism | Encephalomyelitis, Autoimmune, Experimental - immunology | Gene Expression Profiling | Dose-Response Relationship, Drug | Transendothelial and Transepithelial Migration - drug effects | Inflammation - metabolism | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Demyelinating Diseases - immunology | Claudin-3 - metabolism | Female | Indoles - pharmacology | Zonula Occludens-1 Protein - metabolism | Cytokines - immunology | Tight Junctions - drug effects | Tight Junctions - metabolism | Blood-Brain Barrier - immunology | Encephalomyelitis, Autoimmune, Experimental - pathology | Cytokines - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Indoles - immunology | Inflammation - immunology | Protein Kinase C beta - immunology | Demyelinating Diseases - prevention & control | Mice, Inbred Strains | Reverse Transcriptase Polymerase Chain Reaction | Transendothelial and Transepithelial Migration - immunology | Blood-Brain Barrier - drug effects | Endothelial Cells - immunology | Microscopy, Confocal | Animals | Tight Junctions - immunology | Zonula Occludens-1 Protein - immunology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Protein Kinase C beta - metabolism | T-Lymphocytes - immunology | Cell Proliferation - drug effects | Claudin-5 - immunology | Inflammation - prevention & control | Claudin-3 - immunology | Protein Kinase C beta - antagonists & inhibitors | Endothelial Cells - drug effects | Index Medicus | Biological Sciences | enzastaurin
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 07/2006, Volume 177, Issue 1, pp. 566 - 573
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 11/2009, Volume 183, Issue 10, pp. 6041 - 6050
Journal Article
EMBO molecular medicine, ISSN 1757-4684, 01/2014, Volume 6, Issue 2, pp. 226 - 238
...) in two different mouse models of MS. ONX 0914 attenuated disease progression after active and passive induction of experimental autoimmune encephalomyelitis (EAE), both in MOG35–55 and PLP139–151‐induced EAE... 
proteasome | immunoproteasome | experimental autoimmune encephalomyelitis | multiple sclerosis | Experimental autoimmune encephalomyelitis | Multiple sclerosis | Immunoproteasome | Proteasome | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Inflammation - pathology | Peptide Fragments | Spinal Cord - drug effects | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Oligopeptides - therapeutic use | Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis | T-Lymphocytes - metabolism | Spinal Cord - pathology | T-Lymphocytes - drug effects | Female | Proteasome Endopeptidase Complex - immunology | Disease Models, Animal | Proteasome Inhibitors - pharmacology | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Myelin-Oligodendrocyte Glycoprotein | Disease Progression | Proteasome Inhibitors - therapeutic use | Brain - drug effects | Cell Differentiation - immunology | Proteasome Endopeptidase Complex - deficiency | Animals | Brain - pathology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Proteasome Endopeptidase Complex - metabolism | Oligopeptides - pharmacology | Development and progression | Encephalomyelitis | T cells | Analysis | Flow cytometry | Spinal cord | Animal models | Disease | Peptides | Helper cells | Central nervous system | Nervous system | Lymphocytes T | Drug development | Experiments | Immunosuppressive agents | Lymph nodes | Immunology | Demyelination | Lymphocytes | Tumor necrosis factor-TNF | Immunoglobulins | Cytokines | Cloning | Cell differentiation | Experimental allergic encephalomyelitis | CD4 antigen | Monocytes | Proteasomes | Index Medicus
Journal Article