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Science, ISSN 0036-8075, 11/2006, Volume 314, Issue 5801, pp. 997 - 1001
Double-stranded RNA (dsRNA) produced during viral replication is believed to be the critical trigger for activation of antiviral immunity mediated by the RNA... 
Double stranded RNA | 3T3 cells | RNA | HEK293 cells | Cell lines | Viruses | Reports | Genomes | Cellular immunity | Vero cells | Cells | IMMUNITY | NS1 PROTEIN | INTERFERON | REPLICATION | RECOGNITION | DNA | MULTIDISCIPLINARY SCIENCES | INNATE | INDUCTION | VIRAL-INFECTION | VIRUSES | Phosphorylation | Encephalomyocarditis virus - genetics | Humans | Influenza A virus - genetics | Cytoplasm - metabolism | Encephalomyocarditis virus - metabolism | RNA Caps - metabolism | Recombinant Fusion Proteins - metabolism | RNA, Viral - genetics | Transfection | Vesicular stomatitis Indiana virus - metabolism | Influenza A virus - immunology | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | DEAD-box RNA Helicases - metabolism | Dendritic Cells - virology | Cell Line | DEAD Box Protein 58 | Genome, Viral | Influenza A virus - physiology | Vesicular stomatitis Indiana virus - genetics | Interferon-alpha - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Cytoplasm - virology | Interferon-beta - biosynthesis | Viral Nonstructural Proteins - genetics | Encephalomyocarditis virus - immunology | Immunity, Innate | DEAD-box RNA Helicases - genetics | Phosphates - metabolism | Animals | Influenza A virus - metabolism | RNA, Viral - chemistry | Virus Replication | Viral Nonstructural Proteins - metabolism | Mice | Vesicular stomatitis Indiana virus - immunology | Virus diseases | Phosphates | Immune response | Analysis | Research | Structure
Journal Article
Science, ISSN 0036-8075, 10/2013, Volume 342, Issue 6155, pp. 235 - 238
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 24, pp. 11106 - 11121
Journal Article
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3, p. e01535
The RIG-I-like receptors RIG-I, LGP2, and MDA5 initiate an antiviral response that includes production of type I interferons (IFNs). The nature of the RNAs... 
antiviral immunity | EMCV | RIG-I-like receptors | LGP2 | MDA5 | picornavirus | DOUBLE-STRANDED-RNA | ANTIVIRAL RESPONSES | DENDRITIC CELLS | MESSENGER-RNA | STIMULATED GENES | BIOLOGY | INTERFERON REGULATORY FACTOR-3 | RIG-I | 5'-TRIPHOSPHATE RNA | LEADER PROTEIN | VIRAL-INFECTION | RNA Helicases - metabolism | Encephalomyocarditis virus - genetics | Humans | Influenza A virus - genetics | Cercopithecus aethiops | Encephalomyocarditis virus - metabolism | Interferon-Induced Helicase, IFIH1 | RNA, Viral - genetics | Transfection | HEK293 Cells | RNA Helicases - genetics | RNA, Viral - metabolism | Receptor, Interferon alpha-beta - genetics | Interferons - genetics | DEAD-box RNA Helicases - metabolism | Vero Cells | Antiviral Agents - pharmacology | Encephalomyocarditis virus - drug effects | Signal Transduction | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Encephalomyocarditis virus - immunology | Immunity, Innate | Mice, Knockout | Host-Pathogen Interactions | DEAD-box RNA Helicases - genetics | Animals | Influenza A virus - metabolism | Virus Replication | Gene Expression Regulation, Viral | RNA, Antisense - metabolism | Interferons - metabolism | Mice | HeLa Cells | Mutation | RNA, Antisense - genetics | RNA viruses | Medical research | Statistical analysis | Transcription | Nucleotide sequence | Laboratories | Genes | Antisense RNA | Viruses | Innate immunity | Infections | Genomes | Ribonucleic acid--RNA | Clonal deletion | Influenza | Interferon | Research centers | Viral infections | Cancer
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2017, Volume 494, Issue 1-2, pp. 63 - 69
Journal Article
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 498 - 509.e6
Double-stranded RNA (dsRNA) is a common by-product of viral infections and acts as a potent trigger of antiviral immunity. In the nematode , encodes a dsRNA... 
type I interferon | MAVS | bystander immunity | HSV | double-stranded RNA | EMCV | SIDT2 | virus infection | SID-1 | RESPONSES | DOUBLE-STRANDED-RNA | HERPES-SIMPLEX-VIRUS | ACTIVATION | DENDRITIC CELLS | INDUCIBLE GENE-I | ANTIVIRAL SIGNALING PROTEIN | RIG-I | IMMUNOLOGY | INDEPENDENT PATHWAYS | Cardiovirus Infections - genetics | DEAD Box Protein 58 - metabolism | Encephalomyocarditis virus - genetics | Herpes Simplex - genetics | Endosomes - metabolism | Host-Pathogen Interactions - immunology | Lysosomes - metabolism | RNA, Viral - genetics | Female | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Disease Models, Animal | Cell Line | Gene Expression | RNA Transport | Signal Transduction | Membrane Proteins - genetics | Encephalomyocarditis virus - immunology | Gene Knockout Techniques | Immunity, Innate | Toll-Like Receptor 3 - metabolism | Cardiovirus Infections - immunology | Herpes Simplex - immunology | Mice, Knockout | Protein Transport | Animals | Host-Pathogen Interactions - genetics | RNA, Double-Stranded - immunology | Protein Binding | Herpesvirus 1, Human - genetics | Mice | Cytoplasm | Virus diseases | Antiviral agents | Evolution | Wildlife conservation | RNA | Health aspects | Resveratrol | Interferon | Biological response modifiers | Immune response | Cytokines | Double-stranded RNA | Herpes simplex | Viruses | Infections | Immunity | Proteins | Microscopy | Ribonucleic acids | Compartments | Herpes viruses | Cell cycle | Transport | Localization | Transporter
Journal Article