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1. Full Text Toward an Improved Definition of Acute-on-Chronic Liver Failure
by Jalan, Rajiv and Yurdaydin, Cihan and Bajaj, Jasmohan S and Acharya, Subrat K and Arroyo, Vicente and Lin, Han-Chieh and Gines, Pere and Kim, W. Ray and Kamath, Patrick S and World Gastroenterology Org Working and World Gastroenterology Organization Working Party
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 1, pp. 4 - 10
Gastroenterology and Hepatology | SURVIVAL | HEPATITIS | CIRRHOSIS | INJURY | RISK | ORGAN FAILURE | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | TRANSPLANTATION | Liver Cirrhosis - diagnosis | Prognosis | Comorbidity | Humans | End Stage Liver Disease - epidemiology | Liver Failure, Acute - diagnosis | Terminology as Topic | Liver Failure, Acute - epidemiology | End Stage Liver Disease - physiopathology | Liver - physiopathology | Multiple Organ Failure - diagnosis | Disease Progression | Liver Failure, Acute - physiopathology | Liver Cirrhosis - epidemiology | Liver Cirrhosis - physiopathology | End Stage Liver Disease - diagnosis | Multiple Organ Failure - physiopathology
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2. Full Text Risk of end‐stage liver disease, hepatocellular carcinoma, and liver‐related death by fibrosis stage in the hepatitis C Alaska Cohort
by Bruden, Dana J.T and McMahon, Brian J and Townshend‐Bulson, Lisa and Gounder, Prabhu and Gove, Jim and Plotnik, Julia and Homan, Chriss and Hewitt, Annette and Barbour, Youssef and Spradling, Philip R and Simons, Brenna C and McArdle, Susan and Bruce, Michael
Hepatology, ISSN 0270-9139, 07/2017, Volume 66, Issue 1, pp. 37 - 45
Long‐term prospective studies of the outcomes associated with hepatitis C virus (HCV) infection are rare and critical for assessing the potential impact of HCV... 
UNITED-STATES | MORTALITY | VIRUS-INFECTION | GASTROENTEROLOGY & HEPATOLOGY | EPIDEMIOLOGY | NATIVES | End Stage Liver Disease - therapy | Immunohistochemistry | Carcinoma, Hepatocellular - epidemiology | Confidence Intervals | Humans | Middle Aged | End Stage Liver Disease - epidemiology | Hepatitis C, Chronic - therapy | Male | Liver Neoplasms - therapy | Cause of Death | Liver Cirrhosis - epidemiology | Young Adult | Liver Neoplasms - epidemiology | Alaska - epidemiology | Liver Neoplasms - physiopathology | Adult | Female | Retrospective Studies | Hepatitis C, Chronic - epidemiology | Databases, Factual | Carcinoma, Hepatocellular - physiopathology | Comorbidity | Proportional Hazards Models | End Stage Liver Disease - physiopathology | Hepatitis C, Chronic - diagnosis | Disease Progression | Survival Analysis | Liver Cirrhosis - pathology | Aged | Carcinoma, Hepatocellular - therapy | Biopsy, Needle | Liver Cirrhosis - physiopathology | Cohort Studies | Cirrhosis | Liver cancer | Hepatitis | Liver diseases | Developmental stages | Biopsy | Fibrosis | Hepatocellular carcinoma | Hepatitis C | Prospective Cohort | Liver Biopsy | HCV Treatment | Outcomes
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3. Full Text Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury
by Tarlow, Branden D and Finegold, Milton J and Grompe, Markus
Hepatology, ISSN 0270-9139, 07/2014, Volume 60, Issue 1, pp. 278 - 289
Proliferating ducts, termed “oval cells,” have long been thought to be bipotential, that is, produce both biliary ducts and hepatocytes during chronic liver... 
HEPATOCYTES | HOMEOSTASIS | ORIGIN | RAT | REGENERATION | IN-VIVO | GROWTH | FATE | GASTROENTEROLOGY & HEPATOLOGY | LINEAGE | Biliary Tract - cytology | End Stage Liver Disease - genetics | Male | Stem Cells - cytology | Hepatic Duct, Common - cytology | Stem Cells - metabolism | Hepatocytes - cytology | Choline Deficiency - genetics | Female | Chemical and Drug Induced Liver Injury - pathology | Cell Differentiation - physiology | Hepatocytes - transplantation | Hepatocytes - physiology | Disease Models, Animal | Biomarkers - metabolism | SOX9 Transcription Factor - metabolism | Mice, Inbred C57BL | Cells, Cultured | Chemical and Drug Induced Liver Injury - genetics | Choline Deficiency - pathology | Chemical and Drug Induced Liver Injury - physiopathology | End Stage Liver Disease - physiopathology | End Stage Liver Disease - pathology | Cell Lineage - physiology | Mice, Knockout | Choline Deficiency - physiopathology | Animals | Liver - cytology | Mice | SOX9 Transcription Factor - genetics | Chimera | Liver | Rodents | Hepatology
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4. Full Text Objective radiologic assessment of body composition in patients with end-stage liver disease: Going beyond the BMI
by Cruz, Ruy J and Dew, Mary Amanda and Myaskovsky, Larissa and Goodpaster, Bret and Fox, Kristen and Fontes, Paulo and Dimartini, Andrea
Transplantation, ISSN 0041-1337, 02/2013, Volume 95, Issue 4, pp. 617 - 622
Background. Body mass index (BMI) is a commonly used but likely inexact measure of body composition for patients with end-stage liver disease. For this reason,... 
Radiologic assessment | Assessment liver transplant candidates | Cachexia | Body composition | MORTALITY | SURVIVAL | SURGERY | MASS INDEX | MUSCLE MASS | IMMUNOLOGY | INSULIN SENSITIVITY | COMPUTED-TOMOGRAPHY | TRANSPLANTATION | SARCOPENIC OBESITY | CIRRHOSIS | HEMODIALYSIS | ADIPOSE-TISSUE | Predictive Value of Tests | Intra-Abdominal Fat - physiopathology | Liver Transplantation - adverse effects | Humans | Middle Aged | Malnutrition - etiology | Subcutaneous Fat - diagnostic imaging | Male | Tomography, X-Ray Computed | Young Adult | End Stage Liver Disease - surgery | Adiposity | Cachexia - etiology | Adult | End Stage Liver Disease - complications | Female | Obesity - mortality | End Stage Liver Disease - diagnostic imaging | Obesity - diagnostic imaging | Body Mass Index | Cachexia - mortality | Malnutrition - diagnostic imaging | Obesity - complications | Risk Factors | Proportional Hazards Models | Liver Transplantation - mortality | Obesity - physiopathology | Treatment Outcome | Chi-Square Distribution | End Stage Liver Disease - physiopathology | Malnutrition - physiopathology | Intra-Abdominal Fat - diagnostic imaging | End Stage Liver Disease - mortality | Muscle, Skeletal - diagnostic imaging | Subcutaneous Fat - physiopathology | Cachexia - diagnostic imaging | Aged | Cachexia - physiopathology | Obesity | Liver diseases | software | Muscles | Data processing | Survival | Computer programs | Body mass index | Computed tomography | Malnutrition | Liver transplantation
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5. Full Text Assessing liver function by liver enhancement during the hepatobiliary phase with Gd-EOB-DTPA-enhanced MRI at 3 Tesla
by Verloh, N and Haimerl, M and Zeman, F and Schlabeck, M and Barreiros, A and Loss, M and Schreyer, A G and Stroszczynski, C and Fellner, C and Wiggermann, P
European Radiology, ISSN 0938-7994, 5/2014, Volume 24, Issue 5, pp. 1013 - 1019
The purpose of this study was to evaluate the usefulness of Gd-EOB-DTPA-enhanced 3-T MRI to determine the hepatic functional reserve expressed by the model for... 
Medicine & Public Health | Diagnostic Radiology | Magnetic resonance imaging | Model for end-stage liver disease (MELD) | Liver | Internal Medicine | Gd-EOB-DTPA | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | Abdomen | Model for end-stage liver disease ( MELD) | PORTAL-VEIN EMBOLIZATION | DISEASE MELD | MODEL | ORGANIC ANION TRANSPORTERS | CONTRAST AGENT | SIGNAL INTENSITY | HEPATOCELLULAR-CARCINOMA | CIRRHOSIS | MAJOR HEPATIC RESECTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GADOXETATE DISODIUM | Severity of Illness Index | Prospective Studies | Humans | Middle Aged | Liver Diseases - pathology | Liver Function Tests - methods | Magnetic Resonance Imaging - methods | Hepatocytes - pathology | Male | End Stage Liver Disease - physiopathology | End Stage Liver Disease - pathology | Contrast Media | Adult | Female | Liver Diseases - diagnosis | Aged | Liver Diseases - physiopathology | End Stage Liver Disease - diagnosis | Evaluation Studies as Topic | Gadolinium DTPA | Liver diseases | Contrast media
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6. Full Text Exercise as an intervention for patients with end-stage liver disease: Systematic review
by Locklear, Cameron T and Golabi, Pegah and Gerber, Lynn and Younossi, Zobair M
Medicine, ISSN 0025-7974, 10/2018, Volume 97, Issue 42, p. e12774
Background: Various etiologies of chronic liver disease often result in cirrhosis. Beside obvious liver-related complications, cirrhosis also leads to loss of... 
MORTALITY | FATIGUE | exercise | PHYSICAL-EXERCISE | MODEL | MEDICINE, GENERAL & INTERNAL | end-stage liver disease | AEROBIC CAPACITY | MUSCLE STRENGTH | RESISTANCE | IMPROVES | QUALITY-OF-LIFE | cirrhosis | End Stage Liver Disease - therapy | Exercise Therapy - methods | Humans | Exercise Tolerance | Oxygen Consumption | Treatment Outcome | Exercise - physiology | Liver Cirrhosis - therapy | Liver Cirrhosis - physiopathology | End Stage Liver Disease - physiopathology | Liver - physiopathology | Complications and side effects | Care and treatment | Liver cirrhosis | Methods | Exercise therapy
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7. Full Text Oxidative albumin damage in chronic liver failure: Relation to albumin binding capacity, liver dysfunction and survival
by Oettl, Karl and Birner-Gruenberger, Ruth and Spindelboeck, Walter and Stueger, Hans Peter and Dorn, Livia and Stadlbauer, Vanessa and Putz-Bankuti, Csilla and Krisper, Peter and Graziadei, Ivo and Vogel, Wolfgang and Lackner, Carolin and Stauber, Rudolf E
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 59, Issue 5, pp. 978 - 983
Background & Aims Impaired binding function of albumin has been demonstrated in end-stage liver disease. This and other functional disturbances of albumin may... 
Gastroenterology and Hepatology | Oxidative stress | Cirrhosis | Mercaptalbumin | Non-mercaptalbumin | Dansylsarcosine | REDOX STATE | PATHOPHYSIOLOGICAL BASIS | MODEL | BILIRUBIN | HUMAN-SERUM-ALBUMIN | ARTICLE | DECOMPENSATED CIRRHOSIS | DISEASE | CYSTEINE-34 | GASTROENTEROLOGY & HEPATOLOGY | Humans | Middle Aged | Oxidative Stress - physiology | Liver Cirrhosis - mortality | Male | Liver - physiopathology | Case-Control Studies | Sepsis - metabolism | Liver Cirrhosis - metabolism | Adult | Female | Biomarkers - metabolism | Albumins - metabolism | Liver - metabolism | Kaplan-Meier Estimate | End Stage Liver Disease - metabolism | Survival Rate | End Stage Liver Disease - physiopathology | Sepsis - physiopathology | Sepsis - mortality | End Stage Liver Disease - mortality | Aged | Liver Cirrhosis - physiopathology | Protein Binding - physiology | Serum Albumin - metabolism | Albumin | Liver failure
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8. Full Text Liver dysfunction as a predictor of outcomes in patients with advanced heart failure requiring ventricular assist device support: Use of the Model of End-stage Liver Disease (MELD) and MELD eXcluding INR (MELD-XI) scoring system
by Yang, Jonathan A., MD, MPH and Kato, Tomoko S., MD, PhD and Shulman, Brittney P., BS and Takayama, Hiroo, MD, PhD and Farr, Maryjane, MD and Jorde, Ulrich P., MD and Mancini, Donna M., MD and Naka, Yoshifumi, MD, PhD and Schulze, P. Christian, MD, PhD
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2012, Volume 31, Issue 6, pp. 601 - 610
Background Liver dysfunction increases post-surgical morbidity and mortality. The Model of End-stage Liver Disease (MELD) estimates liver function but can be... 
Surgery | ventricular assist device | risk assessment | liver dysfunction | cardiomyopathy | transplantation | MORTALITY | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | RESPIRATORY SYSTEM | CARDIAC HEPATOPATHY | Liver Function Tests | Severity of Illness Index | Heart Failure - complications | Predictive Value of Tests | Reproducibility of Results | Prognosis | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Survival Rate | Treatment Outcome | End Stage Liver Disease - physiopathology | Liver - physiopathology | Heart Failure - therapy | End Stage Liver Disease - etiology | Adult | Female | Aged | Retrospective Studies | End Stage Liver Disease - diagnosis | Heart-Assist Devices | Cohort Studies | Heart Failure - mortality | Heart failure | Care and treatment | Liver diseases | Patient outcomes | Analysis | Anticoagulants (Medicine) | Health aspects
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9. Full Text Pretransplant Portal Vein Recanalization—Transjugular Intrahepatic Portosystemic Shunt in Patients With Complete Obliterative Portal Vein Thrombosis
by Salem, Riad and Vouche, Michael and Baker, Talia and Herrero, Jose Ignacio and Caicedo, Juan Carlos and Fryer, Jonathan and Hickey, Ryan and Habib, Ali and Abecassis, Michael and Koller, Felicitas and Vogelzang, Robert and Desai, Kush and Thornburg, Bartley and Hohlastos, Elias and Resnick, Scott and Lewandowski, Robert J and Sato, Kent and Ryu, Robert K and Ganger, Daniel and Kulik, Laura
Transplantation, ISSN 0041-1337, 11/2015, Volume 99, Issue 11, pp. 2347 - 2355
BACKGROUNDChronic, obliterative portal vein (PV) thrombosis (PVT) represents a relative contraindication to liver transplantation (LT) in some centers. When PV... 
SURGERY | LIVER-TRANSPLANTATION | EFFICACY | CIRRHOTIC-PATIENTS | IMMUNOLOGY | HYPERTENSION | TIPS | TRANSPLANTATION | Predictive Value of Tests | Venous Thrombosis - diagnosis | Liver Transplantation - adverse effects | Humans | Middle Aged | Portal Vein - physiopathology | Male | Patient Selection | Portasystemic Shunt, Transjugular Intrahepatic - mortality | Young Adult | End Stage Liver Disease - surgery | Portasystemic Shunt, Transjugular Intrahepatic - adverse effects | Ultrasonography | Adult | Female | Venous Thrombosis - surgery | Liver Function Tests | Liver Circulation | Chicago | Risk Factors | Kaplan-Meier Estimate | Venous Thrombosis - mortality | Liver Transplantation - mortality | Treatment Outcome | Venous Thrombosis - physiopathology | Portal Vein - diagnostic imaging | Portal Vein - surgery | End Stage Liver Disease - physiopathology | Phlebography | Magnetic Resonance Imaging | End Stage Liver Disease - mortality | Aged | End Stage Liver Disease - diagnosis | Chronic Disease | Vascular Patency
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10. Full Text Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease
by Lai, Jennifer C and Volk, Michael L and Strasburg, Debra and Alexander, Neil
Transplantation, ISSN 0041-1337, 12/2016, Volume 100, Issue 12, pp. 2656 - 2660
BACKGROUNDPhysical frailty, as measured by the Fried Frailty Index, is increasingly recognized as a critical determinant of outcomes in patients with... 
SURGERY | OLDER-ADULTS | SCORES | IMMUNOLOGY | EXERCISE | BALANCE | AGE | TRANSPLANTATION | Severity of Illness Index | Liver Transplantation | Fibrosis - physiopathology | Outcome Assessment (Health Care) | Humans | Middle Aged | Hepatic Encephalopathy - physiopathology | Linear Models | Male | Frail Elderly | End Stage Liver Disease - physiopathology | Activities of Daily Living | Walking | Exercise Test | Outpatients | Female | Isometric Contraction | Aged | Principal Component Analysis
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11. Full Text Quality of Life in Liver Transplant Candidates: Frailty Is a Better Indicator Than Severity of Liver Disease
by Derck, Jordan Elizabeth and Thelen, Angela E and Cron, David C and Friedman, Jeffrey F and Gerebics, Ashley D and Englesbe, Michael J and Sonnenday, Christopher J
Transplantation, ISSN 0041-1337, 02/2015, Volume 99, Issue 2, pp. 340 - 344
BACKGROUNDIn an effort to understand the diminished quality of life (QoL) exhibited by patients with end-stage liver disease (ESLD), we studied the association... 
SURVIVAL | SURGERY | POPULATION | IMPACT | MELD | IMMUNOLOGY | TRANSPLANTATION | Multivariate Analysis | Predictive Value of Tests | Liver Transplantation | Prospective Studies | Gait | Health Status Indicators | Humans | Middle Aged | Male | Mental Health | Motor Activity | End Stage Liver Disease - surgery | End Stage Liver Disease - psychology | Adult | Female | Surveys and Questionnaires | Waiting Lists | Nutritional Status | Hand Strength | Severity of Illness Index | Fatigue - diagnosis | End Stage Liver Disease - physiopathology | Michigan | Fatigue - physiopathology | Quality of Life | Aged | End Stage Liver Disease - diagnosis | Health Status
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12. Full Text Electrolyte and Acid–Base Disturbances in End-Stage Liver Disease: A Physiopathological Approach
by Jiménez, José Víctor and Carrillo-Pérez, Diego Luis and Rosado-Canto, Rodrigo and García-Juárez, Ignacio and Torre, Aldo and Kershenobich, David and Carrillo-Maravilla, Eduardo
Digestive Diseases and Sciences, ISSN 0163-2116, 8/2017, Volume 62, Issue 8, pp. 1855 - 1871
Electrolyte and acid–base disturbances are frequent in patients with end-stage liver disease; the underlying physiopathological mechanisms are often complex... 
Biochemistry, general | Hyponatremia | Medicine & Public Health | Hepatology | Gastroenterology | End-stage liver disease | Hypokalemia | Oncology | Acid–base imbalance | Transplant Surgery | Liver transplantation | VASOPRESSIN RECEPTOR ANTAGONIST | RISK-FACTORS | NITRIC-OXIDE SYNTHASE | URINARY ACIDIFICATION | EXTRAPONTINE MYELINOLYSIS | CIRRHOTIC-PATIENTS | Acid-base imbalance | RENAL TUBULAR-ACIDOSIS | QUALITY-OF-LIFE | GASTROENTEROLOGY & HEPATOLOGY | SERUM SODIUM CONCENTRATION | HEPATIC-ENCEPHALOPATHY | Hypokalemia - etiology | Acid-Base Imbalance - etiology | Humans | Acid-Base Imbalance - physiopathology | Water-Electrolyte Imbalance - etiology | End Stage Liver Disease - physiopathology | Disease Progression | Alkalosis - physiopathology | Hyponatremia - etiology | Hyponatremia - physiopathology | Water-Electrolyte Imbalance - physiopathology | End Stage Liver Disease - complications | Hypokalemia - physiopathology | Alkalosis - etiology | Acids | Electrolytes | Liver diseases
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13. Full Text Bone marrow derived stem cells for the treatment of end-stage liver disease
by Cristina Margini Ranka Vukotic Lucia Brodosi Mauro Bernardi Pietro Andreone
世界胃肠病学杂志：英文版（电子版）, ISSN 1007-9327, 2014, Volume 20, Issue 27, pp. 9098 - 9105
End-stage disease due to liver cirrhosis is an important cause of death worldwide. Cirrhosis results from progressive, extensive fibrosis and impaired... 
s | Hematopoietic | regeneration | Liver | cirrhosis | End stage liver disease | Liver cirrhosis | Hematopoietic stem cells | Liver regeneration | Mesenchymal stem cells | PROGENITOR CELLS | HEPATOCYTES | COLONY-STIMULATING FACTOR | CORD BLOOD | AUTOLOGOUS TRANSPLANTATION | HEPATIC-FIBROSIS | CD34(+) CELLS | DECOMPENSATED CIRRHOSIS | IN-VIVO | GASTROENTEROLOGY & HEPATOLOGY | SHORT-TERM | Liver - pathology | Liver Cirrhosis - diagnosis | Liver Regeneration | Humans | Treatment Outcome | End Stage Liver Disease - physiopathology | Liver - physiopathology | Regenerative Medicine - methods | Disease Progression | Stem Cell Transplantation | End Stage Liver Disease - surgery | Animals | Bone Marrow Transplantation | Liver Cirrhosis - surgery | Liver - surgery | Liver Cirrhosis - physiopathology | End Stage Liver Disease - diagnosis | Review
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14. Full Text Surrogate Endpoints for Clinical Trials in Primary Sclerosing Cholangitis: Review and Results From an International PSC Study Group Consensus Process
by Ponsioen, Cyriel Y and Chapman, Roger W and Chazouillères, Olivier and Hirschfield, Gideon M and Karlsen, Tom H and Lohse, Ansgar W and Pinzani, Massimo and Schrumpf, Erik and Trauner, Michael and Gores, Gregory J
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2016, Volume 63, Issue 4, pp. 1357 - 1367
Primary sclerosing cholangitis (PSC) is a rare, but serious, cholestatic disease for which, to date, no effective therapy exists to halt disease progression... 
FIBROSIS | SURVIVAL | MULTICENTER | DOSE URSODEOXYCHOLIC ACID | THERAPY | ALKALINE-PHOSPHATASE | DOUBLE-BLIND | OUTCOMES | METRONIDAZOLE | GASTROENTEROLOGY & HEPATOLOGY | PERCUTANEOUS LIVER-BIOPSY | Biomarkers - metabolism | Risk Assessment | Humans | Male | Survival Rate | Treatment Outcome | Rare Diseases | End Stage Liver Disease - physiopathology | Evidence-Based Medicine | Consensus | Disease Progression | Cholangitis, Sclerosing - pathology | End Stage Liver Disease - surgery | Liver Transplantation - methods | Clinical Trials, Phase III as Topic | Cholangitis, Sclerosing - therapy | End Stage Liver Disease - mortality | Internationality | Female | Cholangitis, Sclerosing - mortality | Clinical Trials, Phase II as Topic | Needs Assessment | Practice Guidelines as Topic | Transplants & implants | Clinical trials | Histology | Alkaline phosphatase | Liver diseases | Liver | Cholangitis | Bilirubin | Drug development
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