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Journal of Neuroscience, ISSN 0270-6474, 08/2016, Volume 36, Issue 32, pp. 8461 - 8470
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2010, Volume 13, Issue 5, pp. 592 - 600
When chronic alterations in neuronal activity occur, network gain is maintained by global homeostatic scaling of synaptic strength, but the stability of... 
MOUSE-BRAIN | HIPPOCAMPAL SLICE CULTURES | AXON TERMINALS | GAIN-CONTROL | SYNAPTIC-TRANSMISSION | GABA RELEASE | CB1 CANNABINOID RECEPTOR | RAT HIPPOCAMPUS | EXPRESSION | NEUROSCIENCES | PLASTICITY | Cannabinoid Receptor Modulators - metabolism | Cannabinoid Receptor Modulators - pharmacology | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Nerve Net - physiology | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Neural Inhibition - physiology | Drug Interactions | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Neurons - physiology | Benzamides - pharmacology | Homeostasis - drug effects | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Endocannabinoids | Carbamates - pharmacology | Pyrazoles - pharmacology | Synapses - drug effects | Synapses - physiology | Enzyme Inhibitors - pharmacology | Inhibitory Postsynaptic Potentials - physiology | Morpholines - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Calcium Channel Blockers - pharmacology | Down-Regulation - drug effects | Hippocampus - cytology | Arachidonic Acids - pharmacology | Naphthalenes - pharmacology | Agatoxins | Conotoxins - pharmacology | Receptor, Cannabinoid, CB1 - metabolism | Glycerides - pharmacology | Polyamines - pharmacology | Animals | Homeostasis - physiology | Benzoxazines - pharmacology | Polyunsaturated Alkamides - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | In Vitro Techniques | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Brain | Physiological aspects | Homeostasis | Research | Synapses | Injuries | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 06/2012, Volume 74, Issue 5, pp. 801 - 808
The steroid 17β-estradiol (E2) is well known to influence hippocampal functions such as memory, affective behaviors, and epilepsy. There is growing awareness... 
CA1 | EXCITABILITY | STEROIDS | SYNAPSES | ESTROGEN-RECEPTOR-ALPHA | SYNAPTIC-TRANSMISSION | NEURONS | RELEASE | BINDING | NEUROSCIENCES | Cannabinoid Receptor Modulators - metabolism | CA1 Region, Hippocampal - cytology | Electric Stimulation | Estrogens - pharmacology | Male | Receptors, Metabotropic Glutamate - metabolism | Pyridazines - pharmacology | Lactones - pharmacology | Dose-Response Relationship, Drug | Drug Interactions | Castration | Piperidines - pharmacology | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Neurons - drug effects | Endocannabinoids | Estradiol - pharmacology | Pyrazoles - pharmacology | Enzyme Inhibitors - pharmacology | NAD - pharmacology | Cannabinoid Receptor Modulators - agonists | Morpholines - pharmacology | Rats | Biophysics | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Naphthalenes - pharmacology | Patch-Clamp Techniques | Animals | Benzoxazines - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Phenols | In Vitro Techniques | Neural Inhibition - drug effects | Benzodioxoles - pharmacology | Inhibitory Postsynaptic Potentials - drug effects | Brain | Epilepsy | Estrogen | GABA | Hormones, Sex | Estradiol | Studies | Rodents | Gender differences | Behavior | Males | Females | Index Medicus | Presynapse | Emotional behavior | gamma -Aminobutyric acid | Neurosteroids | Memory | Sex | Estrogen receptors | Cannabinoid CB1 receptors | Anandamide | Synaptic transmission | Hippocampus | Steroid hormones | Synapses
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2009, Volume 29, Issue 2, pp. 393 - 401
Glucocorticoids exert an opposing rapid regulation of glutamate and GABA synaptic inputs to hypothalamic magnocellular neurons via the activation of... 
γ | Magnocellular neuron | Endocannabinoid | Nitric oxide | G | GABA | Glucocorticoid | SUPRAOPTIC NUCLEUS | endocannabinoid | glucocorticoid | nitric oxide | ACTIVATION | magnocellular neuron | NITRIC-OXIDE SYNTHASE | NEUROSCIENCES | MEMBRANE ESTROGEN-RECEPTORS | ENDOCANNABINOID RELEASE | PARAVENTRICULAR NUCLEUS | G(alpha) | ADRENALECTOMIZED RATS | NEURONS | VASOPRESSIN | OXYTOCIN | G(beta)gamma | Cannabinoid Receptor Modulators - metabolism | Synaptic Transmission - physiology | gamma-Aminobutyric Acid - metabolism | GTP-Binding Proteins - antagonists & inhibitors | Male | Penicillamine - analogs & derivatives | Patch-Clamp Techniques - methods | Quinoxalines - pharmacology | Dexamethasone - pharmacology | Piperidines - pharmacology | Dronabinol - analogs & derivatives | Neurons - physiology | Nitric Oxide Donors - pharmacology | Dronabinol - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Pyrans - pharmacology | Guanosine Diphosphate - pharmacology | Pyrazoles - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Synapses - drug effects | Synapses - physiology | Penicillamine - pharmacology | Valine - analogs & derivatives | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Thionucleotides - pharmacology | Rats, Sprague-Dawley | Animals | Guanosine Diphosphate - analogs & derivatives | Hypothalamus - cytology | Signal Transduction - drug effects | Arginine - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Glucocorticoids - pharmacology | Glutamic Acid - metabolism | Valine - pharmacology | In Vitro Techniques | Nitric Oxide - metabolism | GTP-Binding Proteins - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2011, Volume 31, Issue 41, pp. 14600 - 14610
Orexin A and B are hypothalamic peptides known to modulate arousal, feeding, and reward via OX1 and OX2 receptors. Orexins are also antinociceptive in the... 
ENERGY HOMEOSTASIS | SYNAPTIC-TRANSMISSION | FEEDING-BEHAVIOR | PHOSPHOLIPASE-C | NEURONS | SPINAL-CORD | DIACYLGLYCEROL LIPASE | STRESS-INDUCED ANALGESIA | NEUROSCIENCES | HIPPOCAMPAL SYNAPSES | HYPOCRETIN OREXIN | Cannabinoid Receptor Modulators - pharmacology | Benzoxazoles - pharmacology | Electric Stimulation | Neural Pathways - drug effects | Rats, Wistar | Receptors, G-Protein-Coupled - metabolism | gamma-Aminobutyric Acid - metabolism | Periaqueductal Gray - drug effects | Male | Receptors, Neuropeptide - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Pain - metabolism | Neural Pathways - physiology | Lactones - pharmacology | Neural Inhibition - physiology | Biphenyl Compounds - pharmacology | Piperidines - pharmacology | Pain - drug therapy | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Urea - analogs & derivatives | Endocannabinoids | Disease Models, Animal | Pyrazoles - pharmacology | Animals, Newborn | Orexins | Enzyme Inhibitors - pharmacology | Receptors, Neuropeptide - antagonists & inhibitors | Morpholines - pharmacology | Rats | Neuropeptides - metabolism | Pain Measurement - drug effects | Orexin Receptors | Pain - pathology | Arachidonic Acids - pharmacology | Naphthalenes - pharmacology | Calcium Channel Blockers | Glycerides - pharmacology | Patch-Clamp Techniques | Animals | Analysis of Variance | Benzoxazines - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Periaqueductal Gray - physiology | In Vitro Techniques | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Urea - pharmacology | Index Medicus
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2012, Volume 66, Issue 3, pp. 251 - 259
Endocannabinoids exhibit vasodilatory properties and reduce blood pressure . However, the influence and mechanism of action of the prominent endocannabinoid,... 
Endocannabinoid | Abnormal cannabidiol | Pulmonary artery | Anandamide | Endothelium | VIRODHAMINE | VASORELAXATION | SMALL MESENTERIC-ARTERY | CANNABINOID RECEPTOR | VESSELS | VASCULATURE | RESISTANCE | PHARMACOLOGY & PHARMACY | CHANNELS | HYPERTENSION | ABNORMAL-CANNABIDIOL | Tetraethylammonium - pharmacology | Endocannabinoids - pharmacology | Rats, Wistar | Capsaicin - pharmacology | Anisoles - pharmacology | Cyclohexanes - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Apamin - pharmacology | Receptors, Cannabinoid - metabolism | TRPV Cation Channels - metabolism | Piperidines - pharmacology | Charybdotoxin - pharmacology | TRPV Cation Channels - antagonists & inhibitors | Potassium Chloride - metabolism | Cannabinoid Receptor Antagonists - pharmacology | Indoles - pharmacology | Benzamides - pharmacology | Potassium Channel Blockers - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Amidohydrolases - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Receptors, Epoprostenol - metabolism | Rats | Amidohydrolases - antagonists & inhibitors | Capsaicin - analogs & derivatives | Imidazoles - pharmacology | Pulmonary Artery - drug effects | Arachidonic Acids - pharmacology | Indomethacin - pharmacology | Receptors, Epoprostenol - antagonists & inhibitors | Animals | Benzyl Compounds - pharmacology | Endothelium, Vascular - metabolism | Prostaglandin-Endoperoxide Synthases - metabolism | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Polyunsaturated Alkamides - pharmacology | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | Hypertension | Enzymes | Vasodilators | Blood vessels | Glycerol | Fatty acids | Pulmonary hypertension | Glycerin | Cannabinoids | Dilatation | Dimethyl sulfoxide | Hydrolases | Indomethacin | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2005, Volume 25, Issue 45, pp. 10537 - 10545
Endocannabinoids are important mediators of short- and long-term synaptic plasticity, but the mechanisms of endocannabinoid release have not been studied... 
Medium spiny neuron | Striatum | Dopamine | Endocannabinoid | L-type calcium channel | mGluR | PURKINJE-CELLS | endocannabinoid | ENDOGENOUS CANNABINOIDS | DEPOLARIZED POSTSYNAPTIC NEURONS | GLUTAMATE UPTAKE | SYNAPTIC PLASTICITY | NEUROSCIENCES | NUCLEUS-ACCUMBENS | HIPPOCAMPAL SYNAPSES | PRESYNAPTIC TERMINALS | striatum | medium spiny neuron | DORSAL STRIATUM | RETROGRADE INHIBITION | dopamine | Cannabinoid Receptor Modulators - metabolism | Sulpiride - pharmacology | Excitatory Postsynaptic Potentials - radiation effects | Cerebellum - drug effects | Benzoxazines | Long-Term Synaptic Depression - drug effects | Corpus Striatum - cytology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Excitatory Postsynaptic Potentials - physiology | Piperidines - pharmacology | Time Factors | Dopamine - physiology | Neurons - drug effects | Electric Stimulation - methods | Endocannabinoids | Pyrazoles - pharmacology | Membrane Potentials - drug effects | Dopamine Agonists - pharmacology | Long-Term Synaptic Depression - physiology | Dopamine - pharmacology | Morpholines - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Nitrendipine - pharmacology | Calcium Channel Blockers - pharmacology | Membrane Potentials - physiology | Rats, Sprague-Dawley | Naphthalenes - pharmacology | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Animals | Dopamine Antagonists - pharmacology | Epistasis, Genetic | Corpus Striatum - physiology | Quinpirole - pharmacology | In Vitro Techniques | Dose-Response Relationship, Radiation | Aspartic Acid - pharmacology | Index Medicus | Cellular | Molecular
Journal Article
Anesthesia and Analgesia, ISSN 0003-2999, 02/2013, Volume 116, Issue 2, pp. 463 - 472
BACKGROUND: Cannabinoid agonists induce norepinephrine release in central, spinal, and peripheral sites. Previous studies suggest an interaction between the... 
NEUROPATHIC PAIN | INFLAMED TISSUE | RAT FRONTAL-CORTEX | ALPHA-2-ADRENOCEPTOR SUBTYPES | FATTY-ACID AMIDE | SPINAL-CORD | ANESTHESIOLOGY | NONCATECHOLIC PHENYLETHYLAMINE DERIVATIVES | NOREPINEPHRINE RELEASE | FORMALIN TEST | DORSAL-ROOT GANGLION | Analgesics - pharmacology | Ethanolamines - pharmacology | Endocannabinoids - pharmacology | Rats, Wistar | Receptor, Cannabinoid, CB2 - agonists | Norepinephrine - physiology | Sympathetic Nervous System - drug effects | Dinoprostone | Male | Cannabinoid Receptor Agonists - pharmacology | Peripheral Nerves - drug effects | Yohimbine - pharmacology | Adrenergic beta-Antagonists - pharmacology | Propranolol - pharmacology | Receptor, Cannabinoid, CB1 - agonists | Adrenergic alpha-1 Receptor Antagonists - pharmacology | Prazosin - pharmacology | Palmitic Acids - pharmacology | Palmitic Acids - antagonists & inhibitors | Morpholines - pharmacology | Rats | Pain Measurement - drug effects | Ethanolamines - antagonists & inhibitors | Polyunsaturated Alkamides - antagonists & inhibitors | Adrenergic alpha-2 Receptor Antagonists - pharmacology | Arachidonic Acids - pharmacology | Animals | Arachidonic Acids - antagonists & inhibitors | Polyunsaturated Alkamides - pharmacology | Adrenergic Uptake Inhibitors - pharmacology | Endocannabinoids - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 06/2013, Volume 69, pp. 115 - 126
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 68, Issue 1, pp. 113 - 126
Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes express CB1Rs that are activated by endocannabinoids released by neurons.... 
ENDOGENOUS CANNABINOIDS | ACTIVATION | CA1 PYRAMIDAL CELLS | EXCITATORY SYNAPSES | NEURONS | LONG-TERM POTENTIATION | GLIAL-CELLS | NEUROSCIENCES | MODULATION | HIPPOCAMPAL SYNAPSES | PLASTICITY | Cannabinoid Receptor Modulators - metabolism | Cannabinoid Receptor Modulators - pharmacology | Glycine - analogs & derivatives | Synaptic Transmission - physiology | Synaptic Transmission - genetics | Calcium - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Resorcinols - pharmacology | Drug Interactions | Photolysis | Piperidines - pharmacology | Pyramidal Cells - physiology | Egtazic Acid - analogs & derivatives | Synaptic Transmission - drug effects | Pyramidal Cells - drug effects | Electric Stimulation - methods | Endocannabinoids | Excitatory Postsynaptic Potentials - genetics | Pyrazoles - pharmacology | Animals, Newborn | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Chelating Agents - pharmacology | Hippocampus - cytology | Mice, Knockout | Astrocytes - physiology | Animals | Egtazic Acid - pharmacology | Glycine - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Benzoates - pharmacology | Thapsigargin - pharmacology | Mice | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - deficiency | In Vitro Techniques | Glutamate | Neurons | Studies | Retina | Transmitters | Index Medicus | Potentiation | Brain | Neurotransmitter release | Astrocytes | Glutamic acid receptors | Cannabinoid CB1 receptors | synaptic depression | Calcium signalling | Pyramidal cells | Synaptic transmission | Endogenous stimuli | Receptor mechanisms | Glutamic acid receptors (metabotropic) | Hippocampus | Neurotransmission
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2005, Volume 102, Issue 52, pp. 19144 - 19149
Central nervous system responses to cannabis are primarily mediated by CB 1 receptors, which couple preferentially to G i/o G proteins. Here, we used calcium... 
Aminoalkylindole | Inositol phosphate | Neurons | Phospholipase C | Analgesics - pharmacology | Calcium - metabolism | Humans | Endoplasmic Reticulum - metabolism | Type C Phospholipases - metabolism | Cytoplasm - metabolism | Benzoxazines | Arachidonic Acids - chemistry | Calcium - chemistry | GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry | Piperidines - pharmacology | Time Factors | Dronabinol - analogs & derivatives | Fluorescent Dyes - pharmacology | Receptor, Cannabinoid, CB1 - chemistry | Neurons - metabolism | Cyclohexanols - pharmacology | Dronabinol - pharmacology | Immunosuppressive Agents - pharmacology | Endocannabinoids | Ryanodine - pharmacology | Pertussis Toxin - pharmacology | Pyrazoles - pharmacology | Cell Line | Glycerides - chemistry | Cannabinoids - chemistry | Morpholines - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | GTP-Binding Protein alpha Subunits, Gq-G11 - physiology | Fura-2 - analogs & derivatives | Naphthalenes - pharmacology | Hippocampus - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Fura-2 - pharmacology | Protein Binding | Protein Conformation | DNA, Complementary - metabolism | Proteins | Neurology | Marijuana | Inhibitor drugs | Calcium | Index Medicus | phospholipase C | Biological Sciences | aminoalkylindole | neurons | inositol phosphate
Journal Article