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Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 1/2011, Volume 461, Issue 1, pp. 1 - 21
Ion channels and transporters play a critical role in ion and fluid homeostasis and thus in normal animal physiology and pathology... 
Signal transduction | Biomedicine | Sodium channel | Human Physiology | Electrophysiology | Anion channel | Cation channel | Aldosterone | Cystic fibrosis transmembrane conductance regulator | Ion channel | Epithelial Na channels | Potassium channel | PHYSIOLOGY | RETICULUM-ASSOCIATED DEGRADATION | CELL-SURFACE EXPRESSION | EPITHELIAL SODIUM-CHANNEL | INDUCIBLE KINASE SGK | TRANSMEMBRANE CONDUCTANCE REGULATOR | NA+ CHANNEL | INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS | ENDOPLASMIC-RETICULUM | K+ CHANNEL | Potassium Channels, Voltage-Gated - physiology | Immediate-Early Proteins - physiology | Protein-Serine-Threonine Kinases - physiology | Humans | Aldosterone - physiology | Endoplasmic Reticulum - physiology | Cystic Fibrosis Transmembrane Conductance Regulator - physiology | Sodium Channels - physiology | Epithelial Sodium Channels - metabolism | Ubiquitin-Protein Ligases - physiology | Ubiquitin - physiology | Endocytosis - physiology | Small Ubiquitin-Related Modifier Proteins - physiology | Calcium Channels - physiology | Animals | Nedd4 Ubiquitin Protein Ligases | Membrane Proteins - metabolism | Ubiquitination - physiology | Vasopressins - physiology | Ion Transport - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Chloride Channels - physiology | Ubiquitin | Corticosteroids | Ligases | Children's hospitals | Physiological aspects | Cystic fibrosis | Membrane proteins
Journal Article
Oncogene, ISSN 1476-5594, 2008, Volume 27, Issue 38, pp. 5148 - 5167
The Notch signaling pathway regulates a diverse array of cell types and cellular processes and is tightly regulated by ligand binding. Both canonical and... 
Endocytosis | Notch ligands | Actin cytoskeleton | Notch signaling | Proteolysis | HUMAN HEMATOPOIETIC STEM | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LUNATIC FRINGE | MIND BOMB | DELTA-ENDOCYTOSIS | CELL BIOLOGY | actin cytoskeleton | ABNORMAL VERTEBRAL SEGMENTATION | ONCOLOGY | SIGNALING PATHWAY | GENETICS & HEREDITY | AXIAL SKELETAL DEFECTS | endocytosis | GROWTH-FACTOR | proteolysis | INTRACELLULAR DOMAIN | Genetic Diseases, Inborn - genetics | Intercellular Signaling Peptides and Proteins - chemistry | Cell Communication - physiology | Receptors, Notch - genetics | Intercellular Signaling Peptides and Proteins - physiology | Ubiquitination | Neoplasms - genetics | Membrane Proteins - physiology | Peptide Hydrolases - physiology | Serrate-Jagged Proteins | Neoplasms - physiopathology | Cell Differentiation - physiology | Calcium-Binding Proteins - chemistry | Protein Structure, Tertiary | Embryonic Development - physiology | Intracellular Signaling Peptides and Proteins | Receptors, Notch - physiology | Glycosylation | Endocytosis - physiology | Protein Interaction Mapping | Membrane Proteins - chemistry | Calcium-Binding Proteins - physiology | Homeostasis - physiology | Ligands | Signal Transduction - physiology | Stem Cells - physiology | Genetic Diseases, Inborn - physiopathology | Protein Processing, Post-Translational | Apoptosis - physiology | Cellular proteins | Care and treatment | Genetic aspects | Cellular signal transduction | Research | Health aspects | Methods | Cancer | Proteins | Signal transduction | Cellular biology | Gene expression
Journal Article
Circulation research, ISSN 0009-7330, 03/2005, Volume 96, Issue 5, pp. 488 - 500
Journal Article
Cell research, ISSN 1001-0602, 2010, Volume 20, Issue 7, pp. 748 - 762
Macroautophagy is a multistep, vacuolar, degradation pathway terminating in the lysosomal compartment, and it is of fundamental importance in tissue... 
酶复合物 | 基因表达调控 | 溶酶体 | 降解途径 | 细胞质 | 哺乳动物细胞 | 成熟期间 | intracellular trafficking | lysosomes | autophagy | proteolysis | cell signaling | BCL-X-L | BECLIN 1 | MEDIATED CLEAVAGE | STARVATION-INDUCED AUTOPHAGY | CELL BIOLOGY | MULTIVESICULAR BODIES | PROTEIN-DEGRADATION | AMINO-ACIDS | VITAMIN-D3 INDUCES AUTOPHAGY | NF-KAPPA-B | UP-REGULATION | Inositol 1,4,5-Trisphosphate Receptors - physiology | N-Ethylmaleimide-Sensitive Proteins - metabolism | Humans | Phagosomes - physiology | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Autophagy - physiology | Forkhead Transcription Factors - physiology | Phosphatidylinositol 3-Kinases - metabolism | Tumor Suppressor Protein p53 - physiology | Lysosomes - metabolism | Membrane Proteins - metabolism | Autophagy - genetics | Protein-Serine-Threonine Kinases - metabolism | Beclin-1 | Protein-Serine-Threonine Kinases - physiology | Hypoxia-Inducible Factor 1 - physiology | Endosomal Sorting Complexes Required for Transport - metabolism | Vacuolar Sorting Protein VPS15 | Apoptosis Regulatory Proteins - metabolism | Endocytosis - physiology | Tumor Suppressor Proteins - physiology | Animals | E2F1 Transcription Factor - physiology | Signal Transduction - physiology | Mice | TOR Serine-Threonine Kinases | Intracellular Signaling Peptides and Proteins - physiology | Phagosomes - genetics
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 04/2011, Volume 31, Issue 15, pp. 5682 - 5692
Short-term facilitation and depression coexist at many CNS synapses. Facilitation, however, has not been fully characterized at hair cell synapses. Using... 
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